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- W2898089813 abstract "Systemic therapy with chemotherapy, immunotherapy or targeted therapy are possible treatments for patients with metastatic lung cancer (stage IV NSCLC). This palliative treatment might prolong survival and reduce symptoms but frequently causes side-effects which may decrease their quality of life (QOL). Little is known about patients’ and oncologists’ goals before starting a new therapy. Therefore, we studied the goals patients and their oncologists have before starting a new treatment for stage IV NSCLC and to what extent these goals are achieved. Patients with stage IV NSCLC were prospectively studied in three hospitals between November 2016 and April 2018. At the start of systemic therapy patients and their oncologists were asked to complete a questionnaire about their treatment goals. These open questions were coded by the investigators. After treatment patients and oncologists were asked to what extent the goals they mentioned before were achieved. The data collection has not been finished yet. Now we report the preliminary results of 240 patients and their oncologists on predefined goals and of 90 patients (whose treatment was finished) and oncologists on achieved goals. Patients and oncologists most often mentioned improvement in QOL (49%;74%), a decrease in tumor size (44%;68%) and life prolongation (43%;50%) as treatment goals. 19% of the patients mentioned cure as a treatment goal. According to patients life prolongation and improvement in QOL were achieved in 56% and 51% respectively. According to oncologists this was only 35% and 32% respectively. Patients and oncologists mention improvement in QOL, decrease in tumor growth and life prolongation most often as treatment goals. It can be questioned whether the 19% of the patients who mentioned cure as a treatment goal think this is a realistic goal or that it is more a sign of hope. After treatment, patients were more optimistic about the treatment effects than their oncologists." @default.
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- W2898089813 date "2018-10-01" @default.
- W2898089813 modified "2023-09-28" @default.
- W2898089813 title "P2.01-14 Preferred and Achieved Goals of Patients with Metastatic Lung Cancer and Their Oncologists in End-of-Life Therapy" @default.
- W2898089813 doi "https://doi.org/10.1016/j.jtho.2018.08.1068" @default.
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