FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898097073> ?p ?o ?g. }

• W2898097073 endingPage "158" @default.
• W2898097073 startingPage "150" @default.
• W2898097073 abstract "Background: Diabetic peripheral neuropathy (DPN) is one of the most common complications of Type 2 diabetes mellitus (T2DM). This study was conducted to investigate the possible association between interleukin-1β (IL-1β) rs16944 /IL-1 receptor antagonist (IL-1Ra) VNTR variants and genetic susceptibility to DPN in a Turkish cohort. Methods: A total of 200 subjects were enrolled in this study, 98 patients with DPN and 102 cases of age and sex-matched healthy controls. Genotyping was performed for all individuals using PCR-RFLP analysis. Results: IL-1β rs16944 CC genotype had a 3.20-fold increased risk for DPN (p=0.0003, OR=3.20, 95% Cl:1.72-5.96). IL-1β rs16944 CT genotype was higher in healthy control than patients (p=0.004). IL-1β rs16944 C allele was higher in the patient group compared to controls while T allele was lower in patients than controls (p=0.003). IL-1Ra VNTR a1/a1 and a2/a2 genotypes were lower in DPN patients while a1/a2 genotype was higher in patients (p=0.045). The patients carrying a1/T haplotype had decreased risk of DPN than control groups (p=0.004). The patients carrying a2/a2 genotype had lower HDL level (p=0.039). The subjects carrying a2/a2 genotype had higher total cholesterol level while the subjects carrying a1/a2 genotype had lower total cholesterol (p=0.026 and p=0.037, respectively). IL-1Ra a1 allele was associated with higher HDL level (p=0.041). Conclusion: Findings of this study indicated that the IL-1β rs16944 and IL-1Ra VNTR variants are probably to be associated with susceptibility DPN risk in a Turkish cohort." @default.
• W2898097073 created "2018-11-02" @default.
• W2898097073 creator A5022515882 @default.
• W2898097073 creator A5032644062 @default.
• W2898097073 creator A5036860510 @default.
• W2898097073 creator A5037019406 @default.
• W2898097073 creator A5057194210 @default.
• W2898097073 creator A5075959125 @default.
• W2898097073 date "2019-02-07" @default.
• W2898097073 modified "2023-09-27" @default.
• W2898097073 title "IL-1β and IL-1Ra Variant Profiles in Turkish Patients with Diabetic Peripheral Neuropathy" @default.
• W2898097073 cites W1491280754 @default.
• W2898097073 cites W1501607445 @default.
• W2898097073 cites W1965419233 @default.
• W2898097073 cites W1969959822 @default.
• W2898097073 cites W1993531176 @default.
• W2898097073 cites W1997895757 @default.
• W2898097073 cites W2012149482 @default.
• W2898097073 cites W2014844877 @default.
• W2898097073 cites W2015072700 @default.
• W2898097073 cites W2018135697 @default.
• W2898097073 cites W2018707257 @default.
• W2898097073 cites W2024378513 @default.
• W2898097073 cites W2032997554 @default.
• W2898097073 cites W2053508422 @default.
• W2898097073 cites W2058455617 @default.
• W2898097073 cites W2061364108 @default.
• W2898097073 cites W2061962106 @default.
• W2898097073 cites W2063307212 @default.
• W2898097073 cites W2072086410 @default.
• W2898097073 cites W2076534373 @default.
• W2898097073 cites W2083277816 @default.
• W2898097073 cites W2084295009 @default.
• W2898097073 cites W2084483597 @default.
• W2898097073 cites W2098374958 @default.
• W2898097073 cites W2108192985 @default.
• W2898097073 cites W2111941249 @default.
• W2898097073 cites W2117121624 @default.
• W2898097073 cites W2121721588 @default.
• W2898097073 cites W2145866317 @default.
• W2898097073 cites W2153214557 @default.
• W2898097073 cites W2160827951 @default.
• W2898097073 cites W2167616988 @default.
• W2898097073 cites W2168248222 @default.
• W2898097073 cites W2169913369 @default.
• W2898097073 cites W2204676649 @default.
• W2898097073 cites W2256262359 @default.
• W2898097073 cites W2324901576 @default.
• W2898097073 cites W2500162161 @default.
• W2898097073 cites W2537078978 @default.
• W2898097073 cites W4242514389 @default.
• W2898097073 doi "https://doi.org/10.2174/1871530318666181022165048" @default.
• W2898097073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30360750" @default.
• W2898097073 hasPublicationYear "2019" @default.
• W2898097073 type Work @default.
• W2898097073 sameAs 2898097073 @default.
• W2898097073 citedByCount "2" @default.
• W2898097073 countsByYear W28980970732020 @default.
• W2898097073 countsByYear W28980970732021 @default.
• W2898097073 crossrefType "journal-article" @default.
• W2898097073 hasAuthorship W2898097073A5022515882 @default.
• W2898097073 hasAuthorship W2898097073A5032644062 @default.
• W2898097073 hasAuthorship W2898097073A5036860510 @default.
• W2898097073 hasAuthorship W2898097073A5037019406 @default.
• W2898097073 hasAuthorship W2898097073A5057194210 @default.
• W2898097073 hasAuthorship W2898097073A5075959125 @default.
• W2898097073 hasConcept C104317684 @default.
• W2898097073 hasConcept C126322002 @default.
• W2898097073 hasConcept C134018914 @default.
• W2898097073 hasConcept C135763542 @default.
• W2898097073 hasConcept C146304588 @default.
• W2898097073 hasConcept C180754005 @default.
• W2898097073 hasConcept C197754878 @default.
• W2898097073 hasConcept C2779901536 @default.
• W2898097073 hasConcept C31467283 @default.
• W2898097073 hasConcept C37463918 @default.
• W2898097073 hasConcept C54355233 @default.
• W2898097073 hasConcept C555293320 @default.
• W2898097073 hasConcept C71924100 @default.
• W2898097073 hasConcept C86803240 @default.
• W2898097073 hasConcept C90924648 @default.
• W2898097073 hasConceptScore W2898097073C104317684 @default.
• W2898097073 hasConceptScore W2898097073C126322002 @default.
• W2898097073 hasConceptScore W2898097073C134018914 @default.
• W2898097073 hasConceptScore W2898097073C135763542 @default.
• W2898097073 hasConceptScore W2898097073C146304588 @default.
• W2898097073 hasConceptScore W2898097073C180754005 @default.
• W2898097073 hasConceptScore W2898097073C197754878 @default.
• W2898097073 hasConceptScore W2898097073C2779901536 @default.
• W2898097073 hasConceptScore W2898097073C31467283 @default.
• W2898097073 hasConceptScore W2898097073C37463918 @default.
• W2898097073 hasConceptScore W2898097073C54355233 @default.
• W2898097073 hasConceptScore W2898097073C555293320 @default.
• W2898097073 hasConceptScore W2898097073C71924100 @default.
• W2898097073 hasConceptScore W2898097073C86803240 @default.
• W2898097073 hasConceptScore W2898097073C90924648 @default.
• W2898097073 hasIssue "2" @default.
• W2898097073 hasLocation W28980970731 @default.

• next