Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898122848> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2898122848 abstract "Thyrotoxicosis with hyperthyroidism is treated with these classical approaches (i) antithyroid drugs to blockade thyroid hormone release and normalize thyroid hormone production and (ii) destruction of the thyroid using radioiodine or surgical removal of the thyroid. The optimal medical therapy, especially for Graves´ disease, remains a subject of debate and there has been little progress in Graves' disease therapeutics over the last decade.Novel treatments of thyrotoxicosis with hyperthyroidism. This includes (i) small molecules such as synthetic thyroid hormone receptor antagonists and environmental molecules and (ii) molecules with interaction between thyroid stimulating hormone (TSH) receptor and TSH receptor antibodies such as M22, ANTAG3, org274179-0, 5C9, and K1-70. Other approaches to Graves´ disease treatment includes immunosuppressive treatment, glucocorticosteroids, rituximab, and intrathyroid injection of dexamethasone. Optimal iodine and selenium supplementation can also be considered.Clinical trials results suggest that novel thyroid treatments involving small molecule therapy, may predict a good future in Graves' disease treatment; however, a greater understanding of these antagonists is needed. Other treatments comprising immunosuppressives have demonstrated a significant reduction of relapse of the disease, but are not recommended by international guidelines." @default.
- W2898122848 created "2018-11-02" @default.
- W2898122848 creator A5086019023 @default.
- W2898122848 date "2018-10-31" @default.
- W2898122848 modified "2023-09-26" @default.
- W2898122848 title "Investigational drugs in early stage clinical trials for thyrotoxicosis with hyperthyroidism" @default.
- W2898122848 cites W1505110999 @default.
- W2898122848 cites W1562308323 @default.
- W2898122848 cites W1562512263 @default.
- W2898122848 cites W1965345171 @default.
- W2898122848 cites W1976454625 @default.
- W2898122848 cites W1978957229 @default.
- W2898122848 cites W1997911832 @default.
- W2898122848 cites W1999444785 @default.
- W2898122848 cites W2000401073 @default.
- W2898122848 cites W2013383421 @default.
- W2898122848 cites W2039119197 @default.
- W2898122848 cites W2048012456 @default.
- W2898122848 cites W2063530353 @default.
- W2898122848 cites W2075476916 @default.
- W2898122848 cites W2087614255 @default.
- W2898122848 cites W2091089626 @default.
- W2898122848 cites W2111127355 @default.
- W2898122848 cites W2126241583 @default.
- W2898122848 cites W2128019213 @default.
- W2898122848 cites W2149848264 @default.
- W2898122848 cites W2150985458 @default.
- W2898122848 cites W2153108911 @default.
- W2898122848 cites W2157437551 @default.
- W2898122848 cites W2158785024 @default.
- W2898122848 cites W2205037416 @default.
- W2898122848 cites W2221663940 @default.
- W2898122848 cites W2275350513 @default.
- W2898122848 cites W2288910126 @default.
- W2898122848 cites W2338074326 @default.
- W2898122848 cites W2466224846 @default.
- W2898122848 cites W2510464317 @default.
- W2898122848 cites W2526952316 @default.
- W2898122848 cites W2531610710 @default.
- W2898122848 cites W2623666974 @default.
- W2898122848 cites W2778160884 @default.
- W2898122848 cites W2797027678 @default.
- W2898122848 cites W4211256569 @default.
- W2898122848 cites W4243225672 @default.
- W2898122848 doi "https://doi.org/10.1080/13543784.2018.1541086" @default.
- W2898122848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30354697" @default.
- W2898122848 hasPublicationYear "2018" @default.
- W2898122848 type Work @default.
- W2898122848 sameAs 2898122848 @default.
- W2898122848 citedByCount "2" @default.
- W2898122848 countsByYear W28981228482020 @default.
- W2898122848 countsByYear W28981228482021 @default.
- W2898122848 crossrefType "journal-article" @default.
- W2898122848 hasAuthorship W2898122848A5086019023 @default.
- W2898122848 hasConcept C126322002 @default.
- W2898122848 hasConcept C134018914 @default.
- W2898122848 hasConcept C2776652619 @default.
- W2898122848 hasConcept C2909564963 @default.
- W2898122848 hasConcept C526584372 @default.
- W2898122848 hasConcept C71315377 @default.
- W2898122848 hasConcept C71924100 @default.
- W2898122848 hasConceptScore W2898122848C126322002 @default.
- W2898122848 hasConceptScore W2898122848C134018914 @default.
- W2898122848 hasConceptScore W2898122848C2776652619 @default.
- W2898122848 hasConceptScore W2898122848C2909564963 @default.
- W2898122848 hasConceptScore W2898122848C526584372 @default.
- W2898122848 hasConceptScore W2898122848C71315377 @default.
- W2898122848 hasConceptScore W2898122848C71924100 @default.
- W2898122848 hasLocation W28981228481 @default.
- W2898122848 hasLocation W28981228482 @default.
- W2898122848 hasOpenAccess W2898122848 @default.
- W2898122848 hasPrimaryLocation W28981228481 @default.
- W2898122848 hasRelatedWork W1998814058 @default.
- W2898122848 hasRelatedWork W2010645160 @default.
- W2898122848 hasRelatedWork W2021841321 @default.
- W2898122848 hasRelatedWork W2026117978 @default.
- W2898122848 hasRelatedWork W2027938488 @default.
- W2898122848 hasRelatedWork W2070480234 @default.
- W2898122848 hasRelatedWork W2078532046 @default.
- W2898122848 hasRelatedWork W2108687096 @default.
- W2898122848 hasRelatedWork W2155312245 @default.
- W2898122848 hasRelatedWork W2095364283 @default.
- W2898122848 isParatext "false" @default.
- W2898122848 isRetracted "false" @default.
- W2898122848 magId "2898122848" @default.
- W2898122848 workType "article" @default.