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- W2898282158 abstract "Malignant Pleural mesothelioma (MPL) is a rare cancer with about 3000 new cases diagnosed each year in the USA. It has poor prognosis with 5 year survival rate of 10%. We performed a national study to assess the impact of demographic and socioeconomic factors on survival of patients with MPL. Patients with MPL diagnosed between 2004-2014 were identified from the National Cancer Database (NCDB). Demographic and socioeconomic factors were collected. The impact on survival was evaluated with Cox regression model after adjusting for the variables. Total of 24826 patients with MPL were included. Median age at diagnosis was 73. Majority of patients were men (75 %), white (93%), insured (97%), lived in a metro area (84%) and treated at an academic facility (64%). Most patients lived in either eastern or central geographic location (45% and 39% respectively). Median overall survival (OS) was 9.8 months. Women had significantly better OS (12.4 months) vs men (9.3 months). (Table 1) OS was better with younger age (16.6 months for patients < 60; 12.4 months for 60-69; 9.9 months for 70-79 and 5.6 months for ≥ 80). Other factors associated with better OS included early stage, lower comorbidity, higher income and treatment at an academic facility. Neither insurance status nor education level had any impact on OS. Race did not impact survival except for Native Americans and Alaskans (represented only 0.2 % of patients) who had better OS compared to Whites. In this largest analysis exploring socio-demographic factors affecting MPL outcomes, we note some disparities. While some of these factors are non-modifiable, others including access to healthcare, income and treating facility type are modifiable. These must be addressed to minimize disparities in outcomes and realize maximal benefit for patients with this incurable malignancy." @default.
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- W2898282158 date "2018-10-01" @default.
- W2898282158 modified "2023-09-30" @default.
- W2898282158 title "P2.06-24 The Impact of Demographic and Socioeconomic Factors on Survival of Patients with Mesothelioma in the USA" @default.
- W2898282158 doi "https://doi.org/10.1016/j.jtho.2018.08.1279" @default.
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