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- W2898307624 abstract "Abstract Background There is evolving evidence about the effect of greenness on health, with findings from several studies showing a relationship with mortality. How greenness can affect mental and neurological systems has not been clearly elucidated. Currently, there are no prospective studies of how greenness can prevent the decline of cognitive function in the elderly in China. Methods We used the 1998 wave of the China Longitudinal Healthy Longevity Survey (CLHLS), a prospective cohort representative of the general elderly population (age ≥80 years) in China. We assessed residential greenness using satellite-derived Normalized Difference Vegetation Index (NDVI) in a 250 m radius around each participant's residential address from 2000 to 2014, and categorised them into quartiles. We assessed cognitive function using an adapted Chinese version of the Mini-Mental State Examination (MMSE). We defined participants with scores less than 24 as having abnormal cognition. We excluded participants with abnormal cognition at baseline in 2000. We used mixed-effects logistic regression to estimate odds ratios (OR) and their corresponding 95% CIs for MMSE scores, adjusted for age, sex, ethnicity, marital status, childhood and adult socioeconomic status, smoking status, alcohol consumption, exercise status, activity of daily living, and time since study entry. Findings There were 2345 participants without cognitive impairment at baseline. The mean cohort age was 90 years (SD 6·6). Participants who developed cognitive impairment over time were more likely to be older, female, not married, have low childhood and adult socioeconomic status, smoke, do not exercise, and had poor physical function at baseline. One quartile increase in NDVI values was associated with an odds ratio (OR) of 0·92 of developing cognitive impairment during follow-up (95% CI 0·86–0·99). Age, sex, marital status, socioeconomic status, smoking, exercise, and activities of daily living were significant predictors of cognitive impairment; 1 year of age was associated with an OR of 1·05 (95% CI 1·03–1·06) of developing cognitive impairment. Interpretation Our findings suggest that an increase in exposure to greenness might be an effective strategy to prevent cognitive decline in the oldest-old (aged ≥80 years), which could have implications for dementia and Alzheimer's disease (now the fifth leading cause of death in China). Funding None" @default.
- W2898307624 created "2018-11-02" @default.
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- W2898307624 date "2018-10-01" @default.
- W2898307624 modified "2023-09-27" @default.
- W2898307624 title "Residential greenness and cognitive function in the oldest-old in China: a prospective cohort study" @default.
- W2898307624 doi "https://doi.org/10.1016/s0140-6736(18)32700-4" @default.
- W2898307624 hasPublicationYear "2018" @default.
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