FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898362009> ?p ?o ?g. }

• W2898362009 endingPage "15" @default.
• W2898362009 startingPage "1" @default.
• W2898362009 abstract "Smallanthus sonchifolius (yacon), a native plant of South America, was observed to improve lipid profile in rodents and humans. This study aimed to investigate the antiobesity properties of yacon roots in a high-fat-diet (HFD) model and the underlying mechanisms. A total of 30 Wistar male rats were divided into five groups (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>6</mml:mn></mml:mrow></mml:math>): the standard chow diet (SD) group was fed a SD; the HFD group was fed a HFD; and the HFD Y340 and HFD Y680 groups were fed a HFD plus yacon flour (340 and 680 mg FOS/kg b. w./day, respectively). HFD Y340 and HFD Y680 rats exhibited marked attenuation of weight gain, a decrease in visceral fat pad weight, a restoration of the serum lipid profile and atherogenic index in a dose-dependent manner, being the higher dose more effective (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mrow><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:mrow></mml:math>). In addition, we found that HFD Y680 rats showed lower glucose and insulin levels, improved glucose tolerance, and insulin sensitivity (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mrow><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.5</mml:mn></mml:mrow></mml:math>). A downregulation of several adipocyte specific-transcription factors, including peroxisome proliferator-activated receptor gamma2 (PPAR- γ 2), CCAAT/enhancer binding protein a (C/EBP-a) and activating protein (aP2) mRNA levels, was determined in the visceral adipose tissue of HFD Y680 rats (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mrow><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:mrow></mml:math>). An improvement of adipokine profile in HFD Y680 rats and decreased serum proinflammatory cytokine levels (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M5><mml:mrow><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:mrow></mml:math>) were determined by ELISA. Decreased macrophage infiltration and F4/80 and MCP-1 expression in the visceral adipose tissue of HFD Y680 rats (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M6><mml:mrow><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.5</mml:mn></mml:mrow></mml:math>), together with a higher pAkt/Akt expression (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M7><mml:mrow><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:mrow></mml:math>) were also observed by immunofluorescence and immunoblotting. A significant increase in glucagon (Gcg) and PYY mRNA levels in distal ileum of HFD Y680 rats (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M8><mml:mrow><mml:mi>p</mml:mi><mml:mo><</mml:mo><mml:mn>0.05</mml:mn></mml:mrow></mml:math>) were also detected. In the second approach, we determined that yacon supplementation potentiates the effects of the HFD reversion to a standard diet. In conclusion, yacon showed antiobesity properties by inhibiting adipogenesis and improving the visceral adipose tissue function." @default.
• W2898362009 created "2018-11-02" @default.
• W2898362009 creator A5051342782 @default.
• W2898362009 creator A5053039896 @default.
• W2898362009 creator A5070441687 @default.
• W2898362009 creator A5088756608 @default.
• W2898362009 date "2018-10-28" @default.
• W2898362009 modified "2023-10-14" @default.
• W2898362009 title "<i>Smallanthus sonchifolius</i> (Yacon) Flour Improves Visceral Adiposity and Metabolic Parameters in High-Fat-Diet-Fed Rats" @default.
• W2898362009 cites W1784628723 @default.
• W2898362009 cites W1879944265 @default.
• W2898362009 cites W1954270231 @default.
• W2898362009 cites W1963979793 @default.
• W2898362009 cites W1966240585 @default.
• W2898362009 cites W1967923229 @default.
• W2898362009 cites W1968269547 @default.
• W2898362009 cites W1968834637 @default.
• W2898362009 cites W1978510451 @default.
• W2898362009 cites W1994719570 @default.
• W2898362009 cites W1996069716 @default.
• W2898362009 cites W1996535102 @default.
• W2898362009 cites W2000328406 @default.
• W2898362009 cites W2003212726 @default.
• W2898362009 cites W2005428158 @default.
• W2898362009 cites W2007655099 @default.
• W2898362009 cites W2008299479 @default.
• W2898362009 cites W2013909000 @default.
• W2898362009 cites W2014989289 @default.
• W2898362009 cites W2029365005 @default.
• W2898362009 cites W2029636599 @default.
• W2898362009 cites W2039181604 @default.
• W2898362009 cites W2046273729 @default.
• W2898362009 cites W2050411195 @default.
• W2898362009 cites W2052609811 @default.
• W2898362009 cites W2057577150 @default.
• W2898362009 cites W2061777582 @default.
• W2898362009 cites W2062607989 @default.
• W2898362009 cites W2068529429 @default.
• W2898362009 cites W2071706440 @default.
• W2898362009 cites W2084146947 @default.
• W2898362009 cites W2084775446 @default.
• W2898362009 cites W2088954672 @default.
• W2898362009 cites W2091759162 @default.
• W2898362009 cites W2097714259 @default.
• W2898362009 cites W2098807021 @default.
• W2898362009 cites W2104085328 @default.
• W2898362009 cites W2107292394 @default.
• W2898362009 cites W2108576543 @default.
• W2898362009 cites W2135675171 @default.
• W2898362009 cites W2143200981 @default.
• W2898362009 cites W2158075769 @default.
• W2898362009 cites W2163208764 @default.
• W2898362009 cites W2164612869 @default.
• W2898362009 cites W2165202791 @default.
• W2898362009 cites W2165456336 @default.
• W2898362009 cites W2166872133 @default.
• W2898362009 cites W2413808534 @default.
• W2898362009 cites W2530291414 @default.
• W2898362009 cites W2548737734 @default.
• W2898362009 cites W2587680743 @default.
• W2898362009 cites W2590097571 @default.
• W2898362009 cites W2596481576 @default.
• W2898362009 cites W2623295368 @default.
• W2898362009 cites W2736028784 @default.
• W2898362009 cites W2792527993 @default.
• W2898362009 cites W2810795937 @default.
• W2898362009 cites W2898362009 @default.
• W2898362009 doi "https://doi.org/10.1155/2018/5341384" @default.
• W2898362009 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6230400" @default.
• W2898362009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30510798" @default.
• W2898362009 hasPublicationYear "2018" @default.
• W2898362009 type Work @default.
• W2898362009 sameAs 2898362009 @default.
• W2898362009 citedByCount "9" @default.
• W2898362009 countsByYear W28983620092019 @default.
• W2898362009 countsByYear W28983620092020 @default.
• W2898362009 countsByYear W28983620092021 @default.
• W2898362009 countsByYear W28983620092022 @default.
• W2898362009 countsByYear W28983620092023 @default.
• W2898362009 crossrefType "journal-article" @default.
• W2898362009 hasAuthorship W2898362009A5051342782 @default.
• W2898362009 hasAuthorship W2898362009A5053039896 @default.
• W2898362009 hasAuthorship W2898362009A5070441687 @default.
• W2898362009 hasAuthorship W2898362009A5088756608 @default.
• W2898362009 hasBestOaLocation W28983620091 @default.
• W2898362009 hasConcept C11413529 @default.
• W2898362009 hasConcept C126322002 @default.
• W2898362009 hasConcept C134018914 @default.
• W2898362009 hasConcept C140793950 @default.
• W2898362009 hasConcept C185592680 @default.
• W2898362009 hasConcept C33923547 @default.
• W2898362009 hasConcept C71924100 @default.
• W2898362009 hasConcept C86803240 @default.
• W2898362009 hasConceptScore W2898362009C11413529 @default.
• W2898362009 hasConceptScore W2898362009C126322002 @default.
• W2898362009 hasConceptScore W2898362009C134018914 @default.
• W2898362009 hasConceptScore W2898362009C140793950 @default.
• W2898362009 hasConceptScore W2898362009C185592680 @default.

• next