FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898485506> ?p ?o ?g. }

• W2898485506 endingPage "582" @default.
• W2898485506 startingPage "573" @default.
• W2898485506 abstract "A facile strategy to synthesize multifunctional nanosized fluorinated graphene oxide (FGO), a novel nanocarrier to controllably and specifically deliver single or mixed anticancer drugs, was demonstrated. FGO was prepared by a mild process to tune its size into nanoscale and modify its surface with oxygen groups, and then functionalize with folic acid (FA) pre-linked amino-polyethylene glycol (PEG), rendering good solubility and specifical targetability toward cancer cells with FA receptors. Moreover, anticancer drugs of doxorubicin and camptothecin were effectively loaded onto FGO-PEG-FA separately or together in a well-controlled manner, and density functional theory calculations revealed that non-covalent interactions were the driving forces for drug loading and fluorine atoms provided more active sites for intermolecular interactions. Good control over surface and structure further endowed FGO unique and roust photoluminescence (PL) as well as high near infrared (NIR) absorbance. The former for the first time made FGO an excellent sensor to visually monitor drug loading by inner filter effects, while the latter guaranteed FGO an effective photothermal therapy (PTT) agent. Based on these, a three-in-one therapy model combined with mixed drug treating and PTT was constructed, and further cancer inhibition experiments revealed that remarkably higher treatment effect was achieved compared to single or two-in-one therapy. The presented work to design, synthesize and modify FGO as a novel nanocarrier and study on the interactions with drugs provided novel insights into developing new drug delivery systems, and the unique PL combined with high NIR absorbance made this work potentially valuable in many fields." @default.
• W2898485506 created "2018-11-02" @default.
• W2898485506 creator A5003234435 @default.
• W2898485506 creator A5015354332 @default.
• W2898485506 creator A5023556088 @default.
• W2898485506 creator A5040712147 @default.
• W2898485506 creator A5047309887 @default.
• W2898485506 creator A5067695216 @default.
• W2898485506 creator A5069778212 @default.
• W2898485506 creator A5070734194 @default.
• W2898485506 creator A5071798264 @default.
• W2898485506 creator A5091161457 @default.
• W2898485506 date "2019-03-01" @default.
• W2898485506 modified "2023-10-17" @default.
• W2898485506 title "Multifunctional fluorescent PEGylated fluorinated graphene for targeted drug delivery: An experiment and DFT study" @default.
• W2898485506 cites W1849299596 @default.
• W2898485506 cites W1966174640 @default.
• W2898485506 cites W1983157397 @default.
• W2898485506 cites W1983401069 @default.
• W2898485506 cites W2060282734 @default.
• W2898485506 cites W2060486979 @default.
• W2898485506 cites W2068287719 @default.
• W2898485506 cites W2075890776 @default.
• W2898485506 cites W2087374774 @default.
• W2898485506 cites W2095642089 @default.
• W2898485506 cites W2149915226 @default.
• W2898485506 cites W2170561730 @default.
• W2898485506 cites W2233776653 @default.
• W2898485506 cites W2256201911 @default.
• W2898485506 cites W2269611697 @default.
• W2898485506 cites W2412466448 @default.
• W2898485506 cites W2469788238 @default.
• W2898485506 cites W2518107319 @default.
• W2898485506 cites W2529898675 @default.
• W2898485506 cites W2547965475 @default.
• W2898485506 cites W2548224342 @default.
• W2898485506 cites W2549750492 @default.
• W2898485506 cites W2561446273 @default.
• W2898485506 cites W2593690650 @default.
• W2898485506 cites W2604225848 @default.
• W2898485506 cites W2612049948 @default.
• W2898485506 cites W2613089336 @default.
• W2898485506 cites W2614603801 @default.
• W2898485506 cites W2622212701 @default.
• W2898485506 cites W2659576948 @default.
• W2898485506 cites W2692479644 @default.
• W2898485506 cites W2724959339 @default.
• W2898485506 cites W2727415841 @default.
• W2898485506 cites W2733279421 @default.
• W2898485506 cites W2733296761 @default.
• W2898485506 cites W2741183871 @default.
• W2898485506 cites W2741423481 @default.
• W2898485506 cites W2742844001 @default.
• W2898485506 cites W2746301517 @default.
• W2898485506 cites W2750857821 @default.
• W2898485506 cites W2755707658 @default.
• W2898485506 cites W2757694089 @default.
• W2898485506 cites W2761556684 @default.
• W2898485506 cites W2764028271 @default.
• W2898485506 cites W2766954181 @default.
• W2898485506 cites W2790341795 @default.
• W2898485506 cites W2793631438 @default.
• W2898485506 cites W2794842294 @default.
• W2898485506 cites W2801855812 @default.
• W2898485506 cites W2802764271 @default.
• W2898485506 cites W2890189207 @default.
• W2898485506 doi "https://doi.org/10.1016/j.dyepig.2018.10.031" @default.
• W2898485506 hasPublicationYear "2019" @default.
• W2898485506 type Work @default.
• W2898485506 sameAs 2898485506 @default.
• W2898485506 citedByCount "57" @default.
• W2898485506 countsByYear W28984855062018 @default.
• W2898485506 countsByYear W28984855062019 @default.
• W2898485506 countsByYear W28984855062020 @default.
• W2898485506 countsByYear W28984855062021 @default.
• W2898485506 countsByYear W28984855062022 @default.
• W2898485506 countsByYear W28984855062023 @default.
• W2898485506 crossrefType "journal-article" @default.
• W2898485506 hasAuthorship W2898485506A5003234435 @default.
• W2898485506 hasAuthorship W2898485506A5015354332 @default.
• W2898485506 hasAuthorship W2898485506A5023556088 @default.
• W2898485506 hasAuthorship W2898485506A5040712147 @default.
• W2898485506 hasAuthorship W2898485506A5047309887 @default.
• W2898485506 hasAuthorship W2898485506A5067695216 @default.
• W2898485506 hasAuthorship W2898485506A5069778212 @default.
• W2898485506 hasAuthorship W2898485506A5070734194 @default.
• W2898485506 hasAuthorship W2898485506A5071798264 @default.
• W2898485506 hasAuthorship W2898485506A5091161457 @default.
• W2898485506 hasConcept C115537861 @default.
• W2898485506 hasConcept C147597530 @default.
• W2898485506 hasConcept C147789679 @default.
• W2898485506 hasConcept C152365726 @default.
• W2898485506 hasConcept C159985019 @default.
• W2898485506 hasConcept C171250308 @default.
• W2898485506 hasConcept C178790620 @default.
• W2898485506 hasConcept C18150654 @default.
• W2898485506 hasConcept C182606246 @default.
• W2898485506 hasConcept C185592680 @default.

• next