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- W2898492820 endingPage "510" @default.
- W2898492820 startingPage "496" @default.
- W2898492820 abstract "Infection with gastrointestinal parasitic nematodes is a major cause of chronic morbidity and economic burden around the world, particularly in low-resource settings. Some parasitic nematode species, including the human-parasitic threadworm Strongyloides stercoralis and human-parasitic hookworms in the genera Ancylostoma and Necator, feature a soil-dwelling infective larval stage that seeks out hosts for infection using a variety of host-emitted sensory cues. Here, we review our current understanding of the behavioral responses of soil-dwelling infective larvae to host-emitted sensory cues, and the molecular and cellular mechanisms that mediate these responses. We also discuss the development of methods for transgenesis and CRISPR/Cas9-mediated targeted mutagenesis in Strongyloides stercoralis and the closely related rat parasite Strongyloides ratti. These methods have established S. stercoralis and S. ratti as genetic model systems for gastrointestinal parasitic nematodes and are enabling more detailed investigations into the neural mechanisms that underlie the sensory-driven behaviors of this medically and economically important class of parasites." @default.
- W2898492820 created "2018-11-02" @default.
- W2898492820 creator A5021071259 @default.
- W2898492820 creator A5036202945 @default.
- W2898492820 date "2018-12-01" @default.
- W2898492820 modified "2023-10-05" @default.
- W2898492820 title "Terror in the dirt: Sensory determinants of host seeking in soil-transmitted mammalian-parasitic nematodes" @default.
- W2898492820 cites W100236420 @default.
- W2898492820 cites W1486592449 @default.
- W2898492820 cites W1498503555 @default.
- W2898492820 cites W1514055214 @default.
- W2898492820 cites W1594676744 @default.
- W2898492820 cites W1599304291 @default.
- W2898492820 cites W1628168006 @default.
- W2898492820 cites W180597922 @default.
- W2898492820 cites W1889720390 @default.
- W2898492820 cites W1893491260 @default.
- W2898492820 cites W1927047146 @default.
- W2898492820 cites W1965404074 @default.
- W2898492820 cites W1966605161 @default.
- W2898492820 cites W1967293029 @default.
- W2898492820 cites W1967691623 @default.
- W2898492820 cites W1973272120 @default.
- W2898492820 cites W1973464749 @default.
- W2898492820 cites W1974604461 @default.
- W2898492820 cites W1976787633 @default.
- W2898492820 cites W1977758477 @default.
- W2898492820 cites W1978428006 @default.
- W2898492820 cites W1978692167 @default.
- W2898492820 cites W1978823643 @default.
- W2898492820 cites W1979477072 @default.
- W2898492820 cites W1980726951 @default.
- W2898492820 cites W1981494766 @default.
- W2898492820 cites W1982002806 @default.
- W2898492820 cites W1982485110 @default.
- W2898492820 cites W1984244186 @default.
- W2898492820 cites W1987158600 @default.
- W2898492820 cites W1989595169 @default.
- W2898492820 cites W1989783465 @default.
- W2898492820 cites W1991307845 @default.
- W2898492820 cites W1991615797 @default.
- W2898492820 cites W1993051018 @default.
- W2898492820 cites W1993272672 @default.
- W2898492820 cites W1993922956 @default.
- W2898492820 cites W1994906047 @default.
- W2898492820 cites W1996756552 @default.
- W2898492820 cites W1997846079 @default.
- W2898492820 cites W1998279724 @default.
- W2898492820 cites W1998876971 @default.
- W2898492820 cites W1999407179 @default.
- W2898492820 cites W2000169552 @default.
- W2898492820 cites W2001920462 @default.
- W2898492820 cites W2004113088 @default.
- W2898492820 cites W2004738638 @default.
- W2898492820 cites W2005237344 @default.
- W2898492820 cites W2007792373 @default.
- W2898492820 cites W2008290466 @default.
- W2898492820 cites W2008872050 @default.
- W2898492820 cites W2009231201 @default.
- W2898492820 cites W2009483096 @default.
- W2898492820 cites W2009842429 @default.
- W2898492820 cites W2010221910 @default.
- W2898492820 cites W2018693734 @default.
- W2898492820 cites W2020169887 @default.
- W2898492820 cites W2021027861 @default.
- W2898492820 cites W2023686402 @default.
- W2898492820 cites W2024454793 @default.
- W2898492820 cites W2025036422 @default.
- W2898492820 cites W2025142458 @default.
- W2898492820 cites W2025177359 @default.
- W2898492820 cites W2027605654 @default.
- W2898492820 cites W2027771004 @default.
- W2898492820 cites W2028224064 @default.
- W2898492820 cites W2028933485 @default.
- W2898492820 cites W2029125407 @default.
- W2898492820 cites W2029287961 @default.
- W2898492820 cites W2032892762 @default.
- W2898492820 cites W2033052818 @default.
- W2898492820 cites W2033500343 @default.
- W2898492820 cites W2034684615 @default.
- W2898492820 cites W2036369728 @default.
- W2898492820 cites W2036468741 @default.
- W2898492820 cites W2037412169 @default.
- W2898492820 cites W2038049618 @default.
- W2898492820 cites W2039419693 @default.
- W2898492820 cites W2040092971 @default.
- W2898492820 cites W2040314018 @default.
- W2898492820 cites W2041321444 @default.
- W2898492820 cites W2041704692 @default.
- W2898492820 cites W2043213600 @default.
- W2898492820 cites W2046622428 @default.
- W2898492820 cites W2047411315 @default.
- W2898492820 cites W2048407401 @default.
- W2898492820 cites W2048433301 @default.
- W2898492820 cites W2048643409 @default.
- W2898492820 cites W2051900861 @default.
- W2898492820 cites W2053593806 @default.
- W2898492820 cites W2054063683 @default.