FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898495785> ?p ?o ?g. }

• W2898495785 abstract "ABSTRACT Mitosis is controlled by a subtle balance between kinase and phosphatase activities that involve the master mitotic kinase cyclin-B–Cdk1 and its antagonizing protein phosphatase 2A-B55 (PP2A-B55). Importantly, the Greatwall (Gwl; known as Mastl in mammals, Rim15 in budding yeast and Ppk18 in fission yeast) kinase pathway regulates PP2A-B55 activity by phosphorylating two proteins, cAMP-regulated phosphoprotein 19 (Arpp19) and α-endosulfine (ENSA). This phosphorylation turns these proteins into potent inhibitors of PP2A-B55, thereby promoting a correct timing and progression of mitosis. In this Cell Science at a Glance article and the accompanying poster, we discuss how Gwl is regulated in space and time, and how the Gwl–Arpp19–ENSA–PP2A-B55 pathway plays an essential role in the control of M and S phases from yeast to human. We also summarize how Gwl modulates oncogenic properties of cells and how nutrient deprivation influences Gwl activity." @default.
• W2898495785 created "2018-11-02" @default.
• W2898495785 creator A5040633585 @default.
• W2898495785 creator A5088501067 @default.
• W2898495785 date "2018-10-15" @default.
• W2898495785 modified "2023-10-06" @default.
• W2898495785 title "Greatwall kinase at a glance" @default.
• W2898495785 cites W124586463 @default.
• W2898495785 cites W1752089945 @default.
• W2898495785 cites W1992868294 @default.
• W2898495785 cites W1999111280 @default.
• W2898495785 cites W2002751569 @default.
• W2898495785 cites W2003826173 @default.
• W2898495785 cites W2007189565 @default.
• W2898495785 cites W2010161828 @default.
• W2898495785 cites W2013724379 @default.
• W2898495785 cites W2026271061 @default.
• W2898495785 cites W2032727166 @default.
• W2898495785 cites W2033364305 @default.
• W2898495785 cites W2063240178 @default.
• W2898495785 cites W2065954246 @default.
• W2898495785 cites W2066324910 @default.
• W2898495785 cites W2070282762 @default.
• W2898495785 cites W2086361185 @default.
• W2898495785 cites W2090898602 @default.
• W2898495785 cites W2091275546 @default.
• W2898495785 cites W2095304369 @default.
• W2898495785 cites W2095346103 @default.
• W2898495785 cites W2096952537 @default.
• W2898495785 cites W2097735632 @default.
• W2898495785 cites W2099503572 @default.
• W2898495785 cites W2104042261 @default.
• W2898495785 cites W2109624445 @default.
• W2898495785 cites W2126559133 @default.
• W2898495785 cites W2131987549 @default.
• W2898495785 cites W2137023945 @default.
• W2898495785 cites W2149870815 @default.
• W2898495785 cites W2151264025 @default.
• W2898495785 cites W2152059298 @default.
• W2898495785 cites W2152321093 @default.
• W2898495785 cites W2156448679 @default.
• W2898495785 cites W2159137685 @default.
• W2898495785 cites W2160825701 @default.
• W2898495785 cites W2165238717 @default.
• W2898495785 cites W2165849156 @default.
• W2898495785 cites W2176498793 @default.
• W2898495785 cites W2218732271 @default.
• W2898495785 cites W2226115533 @default.
• W2898495785 cites W2252588583 @default.
• W2898495785 cites W2271801128 @default.
• W2898495785 cites W2279073676 @default.
• W2898495785 cites W2285630760 @default.
• W2898495785 cites W2293219121 @default.
• W2898495785 cites W2314554583 @default.
• W2898495785 cites W2342067135 @default.
• W2898495785 cites W2510568608 @default.
• W2898495785 cites W2520321244 @default.
• W2898495785 cites W2533641274 @default.
• W2898495785 cites W2566919850 @default.
• W2898495785 cites W2607778805 @default.
• W2898495785 cites W2622262677 @default.
• W2898495785 cites W2742113171 @default.
• W2898495785 cites W2773288863 @default.
• W2898495785 cites W2773576459 @default.
• W2898495785 cites W2885571568 @default.
• W2898495785 doi "https://doi.org/10.1242/jcs.222364" @default.
• W2898495785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30355803" @default.
• W2898495785 hasPublicationYear "2018" @default.
• W2898495785 type Work @default.
• W2898495785 sameAs 2898495785 @default.
• W2898495785 citedByCount "41" @default.
• W2898495785 countsByYear W28984957852019 @default.
• W2898495785 countsByYear W28984957852020 @default.
• W2898495785 countsByYear W28984957852021 @default.
• W2898495785 countsByYear W28984957852022 @default.
• W2898495785 countsByYear W28984957852023 @default.
• W2898495785 crossrefType "journal-article" @default.
• W2898495785 hasAuthorship W2898495785A5040633585 @default.
• W2898495785 hasAuthorship W2898495785A5088501067 @default.
• W2898495785 hasBestOaLocation W28984957851 @default.
• W2898495785 hasConcept C11960822 @default.
• W2898495785 hasConcept C120089663 @default.
• W2898495785 hasConcept C120504264 @default.
• W2898495785 hasConcept C1491633281 @default.
• W2898495785 hasConcept C178666793 @default.
• W2898495785 hasConcept C184235292 @default.
• W2898495785 hasConcept C2777061661 @default.
• W2898495785 hasConcept C2779222958 @default.
• W2898495785 hasConcept C29537977 @default.
• W2898495785 hasConcept C389152 @default.
• W2898495785 hasConcept C53420372 @default.
• W2898495785 hasConcept C55493867 @default.
• W2898495785 hasConcept C6391034 @default.
• W2898495785 hasConcept C86803240 @default.
• W2898495785 hasConcept C93304396 @default.
• W2898495785 hasConcept C95444343 @default.
• W2898495785 hasConcept C97029542 @default.
• W2898495785 hasConceptScore W2898495785C11960822 @default.
• W2898495785 hasConceptScore W2898495785C120089663 @default.
• W2898495785 hasConceptScore W2898495785C120504264 @default.

• next