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• W2898539966 endingPage "46" @default.
• W2898539966 startingPage "39" @default.
• W2898539966 abstract "Abstract Coronary artery stenting following balloon angioplasty represents the gold standard in revascularization of coronary artery stenoses. However, stent deployment as well as percutaneous transluminal coronary angioplasty ( PTCA ) alone causes severe injury of vascular endothelium. The damaged endothelium is intrinsically repaired by locally derived endothelial cells and by circulating endothelial progenitor cells from the blood, leading to re‐population of the denuded regions within several weeks to months. However, the process of re‐endothelialization is often incomplete or dysfunctional, promoting in‐stent thrombosis and restenosis. The molecular and biomechanical mechanisms that influence the process of re‐endothelialization in stented segments are incompletely understood. Once the endothelium is restored, endothelial function might still be impaired. Several strategies have been followed to improve endothelial function after coronary stenting. In this review, the effects of stenting on coronary endothelium are outlined and current and future strategies to improve endothelial function after stent deployment are discussed." @default.
• W2898539966 created "2018-11-02" @default.
• W2898539966 creator A5005034036 @default.
• W2898539966 creator A5020098339 @default.
• W2898539966 date "2018-10-23" @default.
• W2898539966 modified "2023-10-06" @default.
• W2898539966 title "The effects of stenting on coronary endothelium from a molecular biological view: Time for improvement?" @default.
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• W2898539966 doi "https://doi.org/10.1111/jcmm.13936" @default.
• W2898539966 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6307786" @default.

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