Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898611117> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2898611117 endingPage "875" @default.
- W2898611117 startingPage "869" @default.
- W2898611117 abstract "The anticancerous and immunomodulatory activities of Alpinia nigra essential oils and extracts were evaluated in the present study. Besides, volatile constituents of essential oils were also analysed by GC/MS. β-pinene (56.27±2.5%), α-Humulene (13.70±1.55%) were found to be the major constituents in the leaf oil whereas rhizome oil contained β-pinene (38.03± 0.25%), myrtenol (9.35±0.3%) as the main compounds. MCF-7 and HeLa human cancer cell lines were used for evaluation of anticancerous activity. The immunomodulatory activities were examined using human peripheral blood mononuclear cells (PBMC) emphasizing on Th1 and Th2 cytokines. Our results showed that the oil significantly inhibited proliferation of cancer cells in dose-dependent manner. Rhizome oil of Alpinia nigra showed highest percent of inhibition (79 % ± 2.6 for HeLa and 70.9% ± 5.34 for MCF7) at 20 μg/ml concentration. Human PBMC treated with leaf oil showed highest secretion of IFN-γ (102.39 pg/ml) at 40 μg/ml concentration as compared to control (64.56 pg/ ml). The study implies the potential use of oil and extract of A. nigra as potent immunomodulating agent and a therapeutic supplement for breast and cervical cancer treatment. The anti-cancerous and immunomodulatory activities of both oil and extract of A. nigra were shown for the first time in this report." @default.
- W2898611117 created "2018-11-02" @default.
- W2898611117 creator A5006252502 @default.
- W2898611117 creator A5007669203 @default.
- W2898611117 creator A5026768626 @default.
- W2898611117 creator A5028632919 @default.
- W2898611117 creator A5055968597 @default.
- W2898611117 creator A5060160681 @default.
- W2898611117 creator A5089511633 @default.
- W2898611117 date "2018-07-04" @default.
- W2898611117 modified "2023-09-26" @default.
- W2898611117 title "Anticancerous and Immunomodulatory Activities of <i>Alpinia nigra</i> (Gaertn.) Burtt" @default.
- W2898611117 cites W1964922275 @default.
- W2898611117 cites W2004757404 @default.
- W2898611117 cites W2034773878 @default.
- W2898611117 cites W2077812882 @default.
- W2898611117 cites W2088327972 @default.
- W2898611117 cites W2090757343 @default.
- W2898611117 cites W2108319118 @default.
- W2898611117 cites W2111818428 @default.
- W2898611117 cites W2135782709 @default.
- W2898611117 cites W2136110523 @default.
- W2898611117 cites W2137949362 @default.
- W2898611117 cites W2151387867 @default.
- W2898611117 cites W2154009377 @default.
- W2898611117 cites W2164935781 @default.
- W2898611117 cites W2792143499 @default.
- W2898611117 doi "https://doi.org/10.1080/0972060x.2018.1524795" @default.
- W2898611117 hasPublicationYear "2018" @default.
- W2898611117 type Work @default.
- W2898611117 sameAs 2898611117 @default.
- W2898611117 citedByCount "4" @default.
- W2898611117 countsByYear W28986111172020 @default.
- W2898611117 countsByYear W28986111172021 @default.
- W2898611117 countsByYear W28986111172023 @default.
- W2898611117 crossrefType "journal-article" @default.
- W2898611117 hasAuthorship W2898611117A5006252502 @default.
- W2898611117 hasAuthorship W2898611117A5007669203 @default.
- W2898611117 hasAuthorship W2898611117A5026768626 @default.
- W2898611117 hasAuthorship W2898611117A5028632919 @default.
- W2898611117 hasAuthorship W2898611117A5055968597 @default.
- W2898611117 hasAuthorship W2898611117A5060160681 @default.
- W2898611117 hasAuthorship W2898611117A5089511633 @default.
- W2898611117 hasConcept C134550120 @default.
- W2898611117 hasConcept C137061746 @default.
- W2898611117 hasConcept C1491633281 @default.
- W2898611117 hasConcept C185592680 @default.
- W2898611117 hasConcept C202751555 @default.
- W2898611117 hasConcept C2776789170 @default.
- W2898611117 hasConcept C2777278459 @default.
- W2898611117 hasConcept C2777366897 @default.
- W2898611117 hasConcept C2777442669 @default.
- W2898611117 hasConcept C31903555 @default.
- W2898611117 hasConcept C55493867 @default.
- W2898611117 hasConcept C556039675 @default.
- W2898611117 hasConcept C71924100 @default.
- W2898611117 hasConcept C86803240 @default.
- W2898611117 hasConcept C98274493 @default.
- W2898611117 hasConceptScore W2898611117C134550120 @default.
- W2898611117 hasConceptScore W2898611117C137061746 @default.
- W2898611117 hasConceptScore W2898611117C1491633281 @default.
- W2898611117 hasConceptScore W2898611117C185592680 @default.
- W2898611117 hasConceptScore W2898611117C202751555 @default.
- W2898611117 hasConceptScore W2898611117C2776789170 @default.
- W2898611117 hasConceptScore W2898611117C2777278459 @default.
- W2898611117 hasConceptScore W2898611117C2777366897 @default.
- W2898611117 hasConceptScore W2898611117C2777442669 @default.
- W2898611117 hasConceptScore W2898611117C31903555 @default.
- W2898611117 hasConceptScore W2898611117C55493867 @default.
- W2898611117 hasConceptScore W2898611117C556039675 @default.
- W2898611117 hasConceptScore W2898611117C71924100 @default.
- W2898611117 hasConceptScore W2898611117C86803240 @default.
- W2898611117 hasConceptScore W2898611117C98274493 @default.
- W2898611117 hasIssue "4" @default.
- W2898611117 hasLocation W28986111171 @default.
- W2898611117 hasOpenAccess W2898611117 @default.
- W2898611117 hasPrimaryLocation W28986111171 @default.
- W2898611117 hasRelatedWork W1992781601 @default.
- W2898611117 hasRelatedWork W2078318162 @default.
- W2898611117 hasRelatedWork W2143098661 @default.
- W2898611117 hasRelatedWork W2190326739 @default.
- W2898611117 hasRelatedWork W2763655427 @default.
- W2898611117 hasRelatedWork W2991875780 @default.
- W2898611117 hasRelatedWork W2992094169 @default.
- W2898611117 hasRelatedWork W3105463211 @default.
- W2898611117 hasRelatedWork W4213338651 @default.
- W2898611117 hasRelatedWork W4376601531 @default.
- W2898611117 hasVolume "21" @default.
- W2898611117 isParatext "false" @default.
- W2898611117 isRetracted "false" @default.
- W2898611117 magId "2898611117" @default.
- W2898611117 workType "article" @default.