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- W2898629379 abstract "Sensitivity to detect breast cancer (BC) is not high in a dense breast due to masking in mammography. To evaluate the breast density, a volumetric measurement system has been recently developed that measures the percent fibroglandular tissue volume (percent FGV, hereafter termed as FG%) to the breast volume (BV). This study was designed to investigate whether evaluation using FG% can accurately predict the masking risk by comparing with the current standard method of subjective visual estimation (SVE).Using pre-biopsy mammograms of 114 cases histopathologically diagnosed with BC in our facility, SVE based on BI-RADS (5th edition) and volumetric measurements of FG% were conducted. Performance to predict the masking risk was evaluated using the area under the receiver operating characteristic curve (AUC). Relationship between these parameters and the masking risk was evaluated by the adjusted multivariate linear regression analysis.The AUC of SVE values was 0.742 (95% CI 0.641-0.822), while that of FG% was as significantly low as 0.560 (95% CI 0.427-0.685) (P = 0.0014). The SVE values correlated with the detection of BC in mammography (P = 0.0035), but there was no significant relationship with FG% (P = 0.74). The median BV and FGV were 313 cm3 (IQR 191-440) and 63 cm3 (IQR 44-102), respectively. The FGV was comparable to the data for Caucasian women reported in previous studies, but the BV was one-half of the previous data.The current volumetric measurement system to evaluate FG% to BV was found to be insufficient in the performance to predict the masking risk in Japanese women with relatively small-sized breasts." @default.
- W2898629379 created "2018-11-09" @default.
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- W2898629379 date "2018-11-01" @default.
- W2898629379 modified "2023-10-05" @default.
- W2898629379 title "Can quantitative evaluation of mammographic breast density, “volumetric measurement”, predict the masking risk with dense breast tissue? Investigation by comparison with subjective visual estimation by Japanese radiologists" @default.
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- W2898629379 doi "https://doi.org/10.1007/s12282-018-0930-0" @default.
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