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- W2898800924 abstract "Abstract The association between vitamin D deficiency, myalgia, and muscle weakness is well known. However, the molecular basis of vitamin D’s effects on skeletal muscle is incompletely understood and evolving. Case reports in humans describe profound muscle weakness, muscle pain, and type II fiber atrophy in subjects with severe vitamin D deficiency. Animal studies employing models of vitamin D deficiency and aberrant vitamin D signaling have helped to characterize this association. In vitro studies have identified specific pathways by which vitamin D modulates myocytes and influences contraction and anabolism. This chapter discusses clinical aspects of the association between vitamin D deficiency and myopathy, its effects on muscle weakness, muscle pain, physical performance, and falls." @default.
- W2898800924 created "2018-11-09" @default.
- W2898800924 creator A5082276935 @default.
- W2898800924 date "2019-01-01" @default.
- W2898800924 modified "2023-09-26" @default.
- W2898800924 title "Vitamin D Deficiency and Myopathy" @default.
- W2898800924 doi "https://doi.org/10.1016/b978-0-12-810422-4.00024-5" @default.
- W2898800924 hasPublicationYear "2019" @default.
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