FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898813835> ?p ?o ?g. }

• W2898813835 endingPage "2310" @default.
• W2898813835 startingPage "2300" @default.
• W2898813835 abstract "This was a first-in-human study to assess the feasibility, safety, and exploratory efficacy of interatrial shunting for treating high-risk heart failure (HF) in patients with reduced and preserved ejection fraction. A single-arm open-label study of patients with New York Heart Association functional class III or IV HF on optimal therapy was performed at 6 centers. The V-Wave shunt, an hourglass-shaped implant containing a 1-way bioprosthetic valve, was implanted by transseptal catheterization. Clinical, functional, echocardiographic, and hemodynamic evaluations were performed at baseline, 3 and 12 months, and annually (clinical follow-up) thereafter (median follow-up 28 months; interquartile range: 21 to 31 months). A total of 38 patients were enrolled (30 with HF with reduced ejection fraction and 8 with HF with preserved ejection fraction; mean age 66 ± 9 years; 97% and 3% in New York Heart Association functional classes III and IV, respectively), and the shunt device was successfully implanted in all cases without periprocedural mortality. The rate of major device- or procedure-related complications during the first 12 months was 2.6% (periprocedural cardiac tamponade in 1 patient). At 3- and 12-month follow-up, there were improvements in New York Heart Association functional class (classes I and II in 78% and 60% of patients, respectively), quality of life (improvements ≥5 points in 74% and 73% of patients, respectively), and 6-min walk distance (mean increases of 41 ± 63 m and 28 ± 83 m, respectively) (p < 0.02 for all, data available for 36 patients), without changes in objective measures of left- or right-sided function. All shunts were patent at 3 months, but 5 of 36 (14%) had occluded, and another 13 of 36 (36%) were stenotic at the valve by 12 months. Patients with widely patent shunts had lower long-term rates of death, left ventricular assist device placement or heart transplantation (p = 0.001), and HF hospitalization (p = 0.008), along with a reduction of pulmonary capillary wedge pressure (from 23.3 ± 5.4 mm Hg at baseline to 18.0 ± 4.0 mm Hg at 12 months; p = 0.011). Interatrial shunting with the V-Wave system was feasible and safe in patients with HF with reduced and preserved ejection fraction. Improvements in clinical and functional status were observed early and at 12 months despite attenuation of shunt patency in one-half of the patients. Patients with preserved shunt patency tended to maintain clinical benefit during longer term follow-up. Device modification that improves the durability of patency is likely worthwhile before confirmation of these findings in a randomized trial." @default.
• W2898813835 created "2018-11-09" @default.
• W2898813835 creator A5001608378 @default.
• W2898813835 creator A5003478171 @default.
• W2898813835 creator A5006277210 @default.
• W2898813835 creator A5006434008 @default.
• W2898813835 creator A5009728510 @default.
• W2898813835 creator A5013842078 @default.
• W2898813835 creator A5023924226 @default.
• W2898813835 creator A5040373636 @default.
• W2898813835 creator A5045809081 @default.
• W2898813835 creator A5046485954 @default.
• W2898813835 creator A5066384461 @default.
• W2898813835 creator A5075010559 @default.
• W2898813835 creator A5076156498 @default.
• W2898813835 date "2018-11-01" @default.
• W2898813835 modified "2023-10-18" @default.
• W2898813835 title "Interatrial Shunting for Heart Failure" @default.
• W2898813835 cites W2044720410 @default.
• W2898813835 cites W2073890340 @default.
• W2898813835 cites W2083650930 @default.
• W2898813835 cites W2135773383 @default.
• W2898813835 cites W2192260483 @default.
• W2898813835 cites W2310954657 @default.
• W2898813835 cites W2311933573 @default.
• W2898813835 cites W2427094903 @default.
• W2898813835 cites W2531736216 @default.
• W2898813835 cites W2552276063 @default.
• W2898813835 cites W2739017924 @default.
• W2898813835 cites W2769453207 @default.
• W2898813835 cites W3144470180 @default.
• W2898813835 cites W4361868645 @default.
• W2898813835 doi "https://doi.org/10.1016/j.jcin.2018.07.001" @default.
• W2898813835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30391390" @default.
• W2898813835 hasPublicationYear "2018" @default.
• W2898813835 type Work @default.
• W2898813835 sameAs 2898813835 @default.
• W2898813835 citedByCount "68" @default.
• W2898813835 countsByYear W28988138352018 @default.
• W2898813835 countsByYear W28988138352019 @default.
• W2898813835 countsByYear W28988138352020 @default.
• W2898813835 countsByYear W28988138352021 @default.
• W2898813835 countsByYear W28988138352022 @default.
• W2898813835 countsByYear W28988138352023 @default.
• W2898813835 crossrefType "journal-article" @default.
• W2898813835 hasAuthorship W2898813835A5001608378 @default.
• W2898813835 hasAuthorship W2898813835A5003478171 @default.
• W2898813835 hasAuthorship W2898813835A5006277210 @default.
• W2898813835 hasAuthorship W2898813835A5006434008 @default.
• W2898813835 hasAuthorship W2898813835A5009728510 @default.
• W2898813835 hasAuthorship W2898813835A5013842078 @default.
• W2898813835 hasAuthorship W2898813835A5023924226 @default.
• W2898813835 hasAuthorship W2898813835A5040373636 @default.
• W2898813835 hasAuthorship W2898813835A5045809081 @default.
• W2898813835 hasAuthorship W2898813835A5046485954 @default.
• W2898813835 hasAuthorship W2898813835A5066384461 @default.
• W2898813835 hasAuthorship W2898813835A5075010559 @default.
• W2898813835 hasAuthorship W2898813835A5076156498 @default.
• W2898813835 hasConcept C119060515 @default.
• W2898813835 hasConcept C126322002 @default.
• W2898813835 hasConcept C141071460 @default.
• W2898813835 hasConcept C164705383 @default.
• W2898813835 hasConcept C178853913 @default.
• W2898813835 hasConcept C2777385415 @default.
• W2898813835 hasConcept C2778198053 @default.
• W2898813835 hasConcept C2778849806 @default.
• W2898813835 hasConcept C71924100 @default.
• W2898813835 hasConcept C78085059 @default.
• W2898813835 hasConceptScore W2898813835C119060515 @default.
• W2898813835 hasConceptScore W2898813835C126322002 @default.
• W2898813835 hasConceptScore W2898813835C141071460 @default.
• W2898813835 hasConceptScore W2898813835C164705383 @default.
• W2898813835 hasConceptScore W2898813835C178853913 @default.
• W2898813835 hasConceptScore W2898813835C2777385415 @default.
• W2898813835 hasConceptScore W2898813835C2778198053 @default.
• W2898813835 hasConceptScore W2898813835C2778849806 @default.
• W2898813835 hasConceptScore W2898813835C71924100 @default.
• W2898813835 hasConceptScore W2898813835C78085059 @default.
• W2898813835 hasIssue "22" @default.
• W2898813835 hasLocation W28988138351 @default.
• W2898813835 hasLocation W28988138352 @default.
• W2898813835 hasOpenAccess W2898813835 @default.
• W2898813835 hasPrimaryLocation W28988138351 @default.
• W2898813835 hasRelatedWork W2051712573 @default.
• W2898813835 hasRelatedWork W2077083067 @default.
• W2898813835 hasRelatedWork W2091139515 @default.
• W2898813835 hasRelatedWork W2319805938 @default.
• W2898813835 hasRelatedWork W2355594703 @default.
• W2898813835 hasRelatedWork W2361407492 @default.
• W2898813835 hasRelatedWork W2407717929 @default.
• W2898813835 hasRelatedWork W3033076790 @default.
• W2898813835 hasRelatedWork W3155674270 @default.
• W2898813835 hasRelatedWork W3187572025 @default.
• W2898813835 hasVolume "11" @default.
• W2898813835 isParatext "false" @default.
• W2898813835 isRetracted "false" @default.
• W2898813835 magId "2898813835" @default.
• W2898813835 workType "article" @default.