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• W2898813904 abstract "INTRODUCTION: Urinary tract infection (UTI) is a common problem inchildren1 .The incidence varies according to age, race and sex ofchildren2,3. UTI occurs in about 1% of boys and 3-5% of girls 4. In girlsthe first UTI occurs by the age of 5 years with peaks during infancy andtoilet training. After the first UTI 60-80% 0f the girls will develop asecond UTI within 18 months. In boys most UTIs occur during the firstyear of life .UTI is much more common in uncircumcised males. Theprevalence of UTI varies with age. During the 1st year of life; the maleto female ratio is 2.8-5.4:1.Beyond 1-2 years there is a striking femalepreponderance , with a male to female ratio of 1:10.Three to five percent of febrile children are found to haveUTI 6. Symptoms of UTI may be minimal and non-specific in infantsand small children 7. In most cases the first episode of UTI occurs in the1st year of life and it is believed that young growing kidneys are morevulnerable to renal parenchymal damage. UTI may lead to lifethreatening complications like sepsis and renal scarring. Renal scarringis the most common cause of hypertension in later childhood and renalfailure in adulthood.Recognition of UTI in children should be made as early aspossible to prevent these complications 7. Therefore, investigations forearly diagnosis of UTI are of outmost importance 5. In the pediatricpopulation the recurrence rates for UTI are very high.Within 1 year of a first infection, approximately 30% ofboys and 40% of girls will develop a repeat UTI 8. .After the firstepisode, children can expect a recurrence rate of 30%. This rate willdouble for each subsequent infection 9.Anatomic obstruction (posteriorurethral valves, ureteropelvic junction obstruction, ureterovesicalobstruction, and ureterocele) as an etiology for UTI is seen in 2% to10% 10 and 30% to 50% will have vesicoureteral reflux. AIM OF THE STUDY: To study the clinical presentation, laboratorycharacteristics and radiological profile of Urinary TractInfection in hospitalized children between 1 month and 12years of age. DISCUSSION: This study included 246 children in the age group between 1month to 12 years. 15 (6.1%) were less than 1 year, 100 (40.7%) werebetween 1 to 4 years, 75 (30.5%) were between 5 to 8 years and 56(22.7%) between 9 to 12 years of age. Urinary tract infection was morecommon in the 1 to 4 years age group in this study and this is supportedby other studies by Thaer-Al-Momani et al 12 where 49 % were in the 1to 4 years age group and Neelam et al 19where 38.7% belonged to thesame age group.Of the 246 children 143 (58.1%) were males and 103 (41.9%)were females. The male to female ratio in this study is 1.3:1. This is incontrast to the other studies (15, 16) which show a femalepreponderance. The study by Malla et al 16also shows a male to femaleratio of 1:2, 67.2% being females. N.Choudhuri et al13 study oncommunity acquired UTI ,with a male preponderance (53.6%) whencompared to the females(46.4%) supports our study .Another study byG.K.Rai et al 18had 53.3% males and 46.7% females with UTI. Under the less than 1 year age group UTI was morecommon in the male children (8.5%) as reported in other studies 17. Inchildren more than 5 years UTI was common among the females (34%)and this is supported by other studies. CLINICAL PROFILE: The clinical profile of UTI is varied. Symptoms of UTI may beminimal and non-specific in infants and small children. Febrile childrennot suspected of having UTI are as likely to have UTI as those who aresuspected of having UTI. Many studies have been done to study theclinical characteristics of UTI in children and fever is the most commonsymptom in younger children while dysuria and fever is more commonin older children .In this study dysuria is the commonest symptom found in 89.4%followed by fever accounting for 84.5% diarrhea in 24.8%, vomiting in22.7%, abdominal pain in 21.5%, febrile seizures in 6%, dehydration in3.3%, flank pain in 0.4%, recurrences in 6.1% dribbling in 0.8% andpoor urinary stream in 6.1%.Azhar Munir Qureshi et al 15study shows dysuria in 98%, feverin 92%, recurrence in 28%, vomiting in 26%,poor stream in 20% andfailure to thrive in 31%. CONCLUSIONS: 1. Urinary tract infection was more common in children between 1to 4 years.2. In children less than 5 year UTI is common in male children andmore common in female children in the 5 to 12 years age group.3. Dysuria was the most common clinical presentation followed byfever.4. 54.3% of children fell into the Grade I malnutrition group.5. Significant pyuria was found in 38%.6. 59.3% showed significant bacteriuria.7. Escherichia Coli was the commonest urinary pathogen andshowed maximum sensitivity to Amikacin.8. Radiological abnormalities were found in 43% of the children.9. Cystitis was the commonest radiological finding.10. Vesicoureteric reflux was documented in 13.2%.11. Nephrotic syndrome was the most common comorbidity." @default.
• W2898813904 created "2018-11-09" @default.
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• W2898813904 date "2011-04-01" @default.
• W2898813904 modified "2023-09-24" @default.
• W2898813904 title "Clinical, Laboratory and Radiological Profile of Urinary Tract Infection in Children" @default.
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