Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898821714> ?p ?o ?g. }
- W2898821714 endingPage "374" @default.
- W2898821714 startingPage "363" @default.
- W2898821714 abstract "Gold nanoclusters (AuNCs) have been considered to be a promising candidate for hyperthermia-based anticancer therapy. Herein, we introduce albumin-assisted AuNCs composed of small gold nanoparticles (AuNPs, <6 nm) assembled with strands of polyallylamine (PAH), which exhibited strong surface plasmon resonance upon near-infrared (NIR, ∼808 nm) laser irradiation and good in vivo stability. Our albumin-assisted PAH-AuNCs (BSA/PAH-AuNCs) were facilely fabricated as a top-down process by a simple ultrasonication after the preparation of large nano-aggregates of PAH-AuNPs. Albumin played a critical role as a stabilizer and surfactant in making loosely associated large aggregates and thereby producing small gold nanoclusters (∼60 nm) of slightly negative charge upon ultrasonication. The prepared BSA/PAH-AuNCs displayed excellent hyperthermal effects (∼60 °C) in response to ∼808-nm NIR laser irradiation in a 4T1 cell system in vitro and in 4T1 cell tumor xenograft mice in vivo, indicating their remarkable potential to suppress breast cancer growth, without almost no significant toxicity in histology. Consequently, our gold nanoclusters should be considered as a promising photothermal agent that are easy to manufacture and exhibit marked anticancer effects in terms of tumor ablation." @default.
- W2898821714 created "2018-11-09" @default.
- W2898821714 creator A5003476268 @default.
- W2898821714 creator A5012945820 @default.
- W2898821714 creator A5028910874 @default.
- W2898821714 creator A5034418015 @default.
- W2898821714 creator A5043541111 @default.
- W2898821714 creator A5044288629 @default.
- W2898821714 creator A5048381976 @default.
- W2898821714 creator A5049461156 @default.
- W2898821714 creator A5083025417 @default.
- W2898821714 creator A5083751923 @default.
- W2898821714 date "2018-12-01" @default.
- W2898821714 modified "2023-10-17" @default.
- W2898821714 title "Facile fabrication of highly photothermal-effective albumin-assisted gold nanoclusters for treating breast cancer" @default.
- W2898821714 cites W1708688931 @default.
- W2898821714 cites W1903778810 @default.
- W2898821714 cites W1943217154 @default.
- W2898821714 cites W1965097716 @default.
- W2898821714 cites W1967604695 @default.
- W2898821714 cites W1976041621 @default.
- W2898821714 cites W1979232921 @default.
- W2898821714 cites W1980257336 @default.
- W2898821714 cites W1982628018 @default.
- W2898821714 cites W1987483764 @default.
- W2898821714 cites W1990194688 @default.
- W2898821714 cites W1992031451 @default.
- W2898821714 cites W1997203755 @default.
- W2898821714 cites W2001018320 @default.
- W2898821714 cites W2009597964 @default.
- W2898821714 cites W2012902568 @default.
- W2898821714 cites W2015406961 @default.
- W2898821714 cites W2016227717 @default.
- W2898821714 cites W2022583944 @default.
- W2898821714 cites W2022849239 @default.
- W2898821714 cites W2029211399 @default.
- W2898821714 cites W2042292903 @default.
- W2898821714 cites W2042983239 @default.
- W2898821714 cites W2044440155 @default.
- W2898821714 cites W2044763661 @default.
- W2898821714 cites W2044794349 @default.
- W2898821714 cites W2046634775 @default.
- W2898821714 cites W2050197030 @default.
- W2898821714 cites W2055944585 @default.
- W2898821714 cites W2058084763 @default.
- W2898821714 cites W2083710155 @default.
- W2898821714 cites W2087997669 @default.
- W2898821714 cites W2090857211 @default.
- W2898821714 cites W2094534120 @default.
- W2898821714 cites W2106853492 @default.
- W2898821714 cites W2108615682 @default.
- W2898821714 cites W2110572618 @default.
- W2898821714 cites W2135295464 @default.
- W2898821714 cites W2139671304 @default.
- W2898821714 cites W2143463421 @default.
- W2898821714 cites W2168100781 @default.
- W2898821714 cites W2172011109 @default.
- W2898821714 cites W2173601912 @default.
- W2898821714 cites W2187797706 @default.
- W2898821714 cites W2189209546 @default.
- W2898821714 cites W2257175382 @default.
- W2898821714 cites W2288065361 @default.
- W2898821714 cites W2342674120 @default.
- W2898821714 cites W2344172509 @default.
- W2898821714 cites W2397958007 @default.
- W2898821714 cites W2553904358 @default.
- W2898821714 cites W2566489627 @default.
- W2898821714 cites W2580502996 @default.
- W2898821714 cites W2736425644 @default.
- W2898821714 cites W2753358702 @default.
- W2898821714 cites W2754923195 @default.
- W2898821714 cites W2052727360 @default.
- W2898821714 doi "https://doi.org/10.1016/j.ijpharm.2018.10.063" @default.
- W2898821714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30385372" @default.
- W2898821714 hasPublicationYear "2018" @default.
- W2898821714 type Work @default.
- W2898821714 sameAs 2898821714 @default.
- W2898821714 citedByCount "18" @default.
- W2898821714 countsByYear W28988217142019 @default.
- W2898821714 countsByYear W28988217142020 @default.
- W2898821714 countsByYear W28988217142021 @default.
- W2898821714 countsByYear W28988217142022 @default.
- W2898821714 countsByYear W28988217142023 @default.
- W2898821714 crossrefType "journal-article" @default.
- W2898821714 hasAuthorship W2898821714A5003476268 @default.
- W2898821714 hasAuthorship W2898821714A5012945820 @default.
- W2898821714 hasAuthorship W2898821714A5028910874 @default.
- W2898821714 hasAuthorship W2898821714A5034418015 @default.
- W2898821714 hasAuthorship W2898821714A5043541111 @default.
- W2898821714 hasAuthorship W2898821714A5044288629 @default.
- W2898821714 hasAuthorship W2898821714A5048381976 @default.
- W2898821714 hasAuthorship W2898821714A5049461156 @default.
- W2898821714 hasAuthorship W2898821714A5083025417 @default.
- W2898821714 hasAuthorship W2898821714A5083751923 @default.
- W2898821714 hasConcept C104628117 @default.
- W2898821714 hasConcept C104819515 @default.
- W2898821714 hasConcept C106847996 @default.
- W2898821714 hasConcept C13965031 @default.