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- W2898830245 abstract "Leukocyte telomere shortening reflects stress burdens and has been associated with cardiac events. However, the patient-specific clinical value of telomere assessment remains unknown. Moreover, telomere shortening cannot be inferred from a single telomere length assessment. The authors investigated and developed a novel strategy for gauging leukocyte telomere shortening using autologous cardiac atrial referencing. Using multitissue assessments from 163 patients who underwent cardiovascular surgery, we determined that the cardiac atrium-leukocyte telomere length difference predicted post-operative complexity. This constituted the first evidence that a single-time assessment of telomere dynamics might be salient to acute cardiac care." @default.
- W2898830245 created "2018-11-09" @default.
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- W2898830245 date "2018-10-01" @default.
- W2898830245 modified "2023-10-18" @default.
- W2898830245 title "Cardiac-Referenced Leukocyte Telomere Length and Outcomes After Cardiovascular Surgery" @default.
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- W2898830245 doi "https://doi.org/10.1016/j.jacbts.2018.07.004" @default.
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