FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898830414> ?p ?o ?g. }

• W2898830414 endingPage "779" @default.
• W2898830414 startingPage "773" @default.
• W2898830414 abstract "Cachexia, observed in most cancer patients, is a syndrome that includes wasting of bodily energy reserves and is characterized by muscle atrophy and fat loss. We have previously demonstrated that isoflavones, such as genistein and daidzein, prevent muscle wasting in tumor-bearing mice. In this study, we examined the effect of morin, a flavonoid, on cachexia. The wet weight and myofiber size of muscles in Lewis lung carcinoma (LLC) cell-bearing mice fed a normal diet were decreased, compared with those in control mice fed a normal diet. In contrast, intake of morin prevented the reduction of muscle wet weight and myofiber size. Moreover, the tumor weight in mice fed the morin diet was lower than that in mice fed the normal diet. Both cell viability and protein synthetic ability of LLC cells were reduced by treatment with morin, but C2C12 myotubes were not affected. Binding assay using morin-conjugated magnetic beads identified ribosomal protein S10 (RPS10) as a target protein of morin. Consistent with the result of morin treatment, knockdown of RPS10 suppressed LLC cell viability. These results suggest that morin indirectly prevents muscle wasting induced by cancer cachexia by suppressing cancer growth via binding to RPS10." @default.
• W2898830414 created "2018-11-09" @default.
• W2898830414 creator A5022816821 @default.
• W2898830414 creator A5026582604 @default.
• W2898830414 creator A5048401879 @default.
• W2898830414 creator A5052374487 @default.
• W2898830414 creator A5054073636 @default.
• W2898830414 creator A5054529674 @default.
• W2898830414 creator A5056194022 @default.
• W2898830414 creator A5066386536 @default.
• W2898830414 creator A5072448709 @default.
• W2898830414 creator A5076263473 @default.
• W2898830414 creator A5082935009 @default.
• W2898830414 creator A5091701897 @default.
• W2898830414 date "2018-12-01" @default.
• W2898830414 modified "2023-09-24" @default.
• W2898830414 title "Morin suppresses cachexia-induced muscle wasting by binding to ribosomal protein S10 in carcinoma cells" @default.
• W2898830414 cites W1974940171 @default.
• W2898830414 cites W1980473722 @default.
• W2898830414 cites W2005875349 @default.
• W2898830414 cites W2009514561 @default.
• W2898830414 cites W2015914204 @default.
• W2898830414 cites W2030996065 @default.
• W2898830414 cites W2032229052 @default.
• W2898830414 cites W2033843688 @default.
• W2898830414 cites W2045816756 @default.
• W2898830414 cites W2060522181 @default.
• W2898830414 cites W2079838847 @default.
• W2898830414 cites W2088412411 @default.
• W2898830414 cites W2107251975 @default.
• W2898830414 cites W2137207137 @default.
• W2898830414 cites W2139583741 @default.
• W2898830414 cites W2158899005 @default.
• W2898830414 cites W2257594987 @default.
• W2898830414 cites W2322553195 @default.
• W2898830414 cites W2342628474 @default.
• W2898830414 cites W2487659136 @default.
• W2898830414 cites W2531876551 @default.
• W2898830414 cites W2761098241 @default.
• W2898830414 cites W2790174680 @default.
• W2898830414 cites W2803194076 @default.
• W2898830414 cites W4245546812 @default.
• W2898830414 cites W4248195705 @default.
• W2898830414 doi "https://doi.org/10.1016/j.bbrc.2018.10.184" @default.
• W2898830414 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30389140" @default.
• W2898830414 hasPublicationYear "2018" @default.
• W2898830414 type Work @default.
• W2898830414 sameAs 2898830414 @default.
• W2898830414 citedByCount "14" @default.
• W2898830414 countsByYear W28988304142019 @default.
• W2898830414 countsByYear W28988304142020 @default.
• W2898830414 countsByYear W28988304142021 @default.
• W2898830414 countsByYear W28988304142022 @default.
• W2898830414 countsByYear W28988304142023 @default.
• W2898830414 crossrefType "journal-article" @default.
• W2898830414 hasAuthorship W2898830414A5022816821 @default.
• W2898830414 hasAuthorship W2898830414A5026582604 @default.
• W2898830414 hasAuthorship W2898830414A5048401879 @default.
• W2898830414 hasAuthorship W2898830414A5052374487 @default.
• W2898830414 hasAuthorship W2898830414A5054073636 @default.
• W2898830414 hasAuthorship W2898830414A5054529674 @default.
• W2898830414 hasAuthorship W2898830414A5056194022 @default.
• W2898830414 hasAuthorship W2898830414A5066386536 @default.
• W2898830414 hasAuthorship W2898830414A5072448709 @default.
• W2898830414 hasAuthorship W2898830414A5076263473 @default.
• W2898830414 hasAuthorship W2898830414A5082935009 @default.
• W2898830414 hasAuthorship W2898830414A5091701897 @default.
• W2898830414 hasConcept C121608353 @default.
• W2898830414 hasConcept C126322002 @default.
• W2898830414 hasConcept C134018914 @default.
• W2898830414 hasConcept C142724271 @default.
• W2898830414 hasConcept C170493617 @default.
• W2898830414 hasConcept C185592680 @default.
• W2898830414 hasConcept C207200792 @default.
• W2898830414 hasConcept C2776263037 @default.
• W2898830414 hasConcept C2777704314 @default.
• W2898830414 hasConcept C2779428903 @default.
• W2898830414 hasConcept C2779764123 @default.
• W2898830414 hasConcept C2779959927 @default.
• W2898830414 hasConcept C2779968248 @default.
• W2898830414 hasConcept C3763915 @default.
• W2898830414 hasConcept C502942594 @default.
• W2898830414 hasConcept C60278653 @default.
• W2898830414 hasConcept C71924100 @default.
• W2898830414 hasConcept C86803240 @default.
• W2898830414 hasConcept C88045685 @default.
• W2898830414 hasConceptScore W2898830414C121608353 @default.
• W2898830414 hasConceptScore W2898830414C126322002 @default.
• W2898830414 hasConceptScore W2898830414C134018914 @default.
• W2898830414 hasConceptScore W2898830414C142724271 @default.
• W2898830414 hasConceptScore W2898830414C170493617 @default.
• W2898830414 hasConceptScore W2898830414C185592680 @default.
• W2898830414 hasConceptScore W2898830414C207200792 @default.
• W2898830414 hasConceptScore W2898830414C2776263037 @default.
• W2898830414 hasConceptScore W2898830414C2777704314 @default.
• W2898830414 hasConceptScore W2898830414C2779428903 @default.
• W2898830414 hasConceptScore W2898830414C2779764123 @default.
• W2898830414 hasConceptScore W2898830414C2779959927 @default.

• next