Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898833818> ?p ?o ?g. }
- W2898833818 endingPage "602" @default.
- W2898833818 startingPage "594" @default.
- W2898833818 abstract "Blinatumomab (Blincyto, Amgen), a bi-specific antibody, is a first-in-class, targeted immunotherapy agent for treatment of B-cell malignancies with a novel mechanism of action which involves in-vivo engagement of the patient's T cells with CD19-expressing tumour cells. Clinical trials have demonstrated its efficacy in relapsed B-cell Acute Lymphoblastic Leukaemia (B-ALL) and B-cell Non-Hodgkin's Lymphoma including in patients who are refractory to chemotherapy. This review summarises the development and design of Blinatumomab, the outcome of clinical studies demonstrating its efficacy and how to manage the administration, practically, including relevant toxicities. We compare and contrast it to other emerging agents for treatment of B-cell malignancies." @default.
- W2898833818 created "2018-11-09" @default.
- W2898833818 creator A5025025997 @default.
- W2898833818 creator A5047403549 @default.
- W2898833818 creator A5082725388 @default.
- W2898833818 date "2018-11-20" @default.
- W2898833818 modified "2023-10-16" @default.
- W2898833818 title "Blinatumomab, a bispecific B-cell and T-cell engaging antibody, in the treatment of B-cell malignancies" @default.
- W2898833818 cites W1488000644 @default.
- W2898833818 cites W1525580671 @default.
- W2898833818 cites W1967348190 @default.
- W2898833818 cites W1967512987 @default.
- W2898833818 cites W1974084203 @default.
- W2898833818 cites W1977380325 @default.
- W2898833818 cites W2004437400 @default.
- W2898833818 cites W2029650920 @default.
- W2898833818 cites W2031089532 @default.
- W2898833818 cites W2031452426 @default.
- W2898833818 cites W2038414910 @default.
- W2898833818 cites W2053754416 @default.
- W2898833818 cites W2055482234 @default.
- W2898833818 cites W2058015212 @default.
- W2898833818 cites W2072078686 @default.
- W2898833818 cites W2104722860 @default.
- W2898833818 cites W2105400883 @default.
- W2898833818 cites W2106928992 @default.
- W2898833818 cites W2107925822 @default.
- W2898833818 cites W2108465006 @default.
- W2898833818 cites W2109388187 @default.
- W2898833818 cites W2118241155 @default.
- W2898833818 cites W2126232974 @default.
- W2898833818 cites W2127018518 @default.
- W2898833818 cites W2127742735 @default.
- W2898833818 cites W2128491464 @default.
- W2898833818 cites W2134118606 @default.
- W2898833818 cites W2134861285 @default.
- W2898833818 cites W2141019574 @default.
- W2898833818 cites W2154066874 @default.
- W2898833818 cites W2167882988 @default.
- W2898833818 cites W2170513194 @default.
- W2898833818 cites W2223191381 @default.
- W2898833818 cites W2236959863 @default.
- W2898833818 cites W2279127916 @default.
- W2898833818 cites W2412725897 @default.
- W2898833818 cites W2419639370 @default.
- W2898833818 cites W2520695016 @default.
- W2898833818 cites W2521076777 @default.
- W2898833818 cites W2529226476 @default.
- W2898833818 cites W2576962736 @default.
- W2898833818 cites W2582696216 @default.
- W2898833818 cites W2591709377 @default.
- W2898833818 cites W2599899418 @default.
- W2898833818 cites W2613210669 @default.
- W2898833818 cites W2729141564 @default.
- W2898833818 cites W2752517775 @default.
- W2898833818 cites W2783032930 @default.
- W2898833818 cites W2787145330 @default.
- W2898833818 cites W2787301955 @default.
- W2898833818 cites W2787621143 @default.
- W2898833818 cites W2789799267 @default.
- W2898833818 cites W2796740086 @default.
- W2898833818 cites W2800949131 @default.
- W2898833818 cites W2801146643 @default.
- W2898833818 cites W2810973315 @default.
- W2898833818 cites W2883570202 @default.
- W2898833818 cites W4246079859 @default.
- W2898833818 doi "https://doi.org/10.1080/21645515.2018.1540828" @default.
- W2898833818 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6605719" @default.
- W2898833818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30380973" @default.
- W2898833818 hasPublicationYear "2018" @default.
- W2898833818 type Work @default.
- W2898833818 sameAs 2898833818 @default.
- W2898833818 citedByCount "21" @default.
- W2898833818 countsByYear W28988338182019 @default.
- W2898833818 countsByYear W28988338182020 @default.
- W2898833818 countsByYear W28988338182021 @default.
- W2898833818 countsByYear W28988338182022 @default.
- W2898833818 countsByYear W28988338182023 @default.
- W2898833818 crossrefType "journal-article" @default.
- W2898833818 hasAuthorship W2898833818A5025025997 @default.
- W2898833818 hasAuthorship W2898833818A5047403549 @default.
- W2898833818 hasAuthorship W2898833818A5082725388 @default.
- W2898833818 hasBestOaLocation W28988338181 @default.
- W2898833818 hasConcept C126322002 @default.
- W2898833818 hasConcept C143998085 @default.
- W2898833818 hasConcept C159654299 @default.
- W2898833818 hasConcept C203014093 @default.
- W2898833818 hasConcept C2776090121 @default.
- W2898833818 hasConcept C2777701055 @default.
- W2898833818 hasConcept C2778020697 @default.
- W2898833818 hasConcept C2778453870 @default.
- W2898833818 hasConcept C2778957590 @default.
- W2898833818 hasConcept C2779338263 @default.
- W2898833818 hasConcept C502942594 @default.
- W2898833818 hasConcept C535046627 @default.
- W2898833818 hasConcept C71924100 @default.
- W2898833818 hasConcept C8891405 @default.
- W2898833818 hasConceptScore W2898833818C126322002 @default.