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- W2898845439 abstract "Although nerve biopsy is a classical approach, it still plays a role in the diagnosis and elucidation of the pathophysiology of neuropathy.1 There are two major techniques used to assess the morphology of nerve fibres in the longitudinal direction; one involves cutting glutaraldehyde-fixed epoxy-resin-embedded specimens into longitudinal sections and the other involves teasing the nerve fibres. Longitudinal sections are suitable for fine structural assessments using transmission electron microscopy to demonstrate, for example, paranodal pathology in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) displaying anti-neurofascin 155 antibodies.2 However, longitudinal sections are not useful for viewing complete pictures of long lesions that extend over several nodes of Ranvier.Conversely, teased-fibre preparations enable observations of long nerve fibre …" @default.
- W2898845439 created "2018-11-09" @default.
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- W2898845439 date "2018-11-01" @default.
- W2898845439 modified "2023-09-23" @default.
- W2898845439 title "New teased-fibre definitions represent specific mechanisms of neuropathy" @default.
- W2898845439 cites W2120990932 @default.
- W2898845439 cites W2570694545 @default.
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- W2898845439 doi "https://doi.org/10.1136/jnnp-2018-319493" @default.
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- W2898845439 hasPublicationYear "2018" @default.
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