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- W2898863223 endingPage "103" @default.
- W2898863223 startingPage "79" @default.
- W2898863223 abstract "Our body not only responds to environmental changes but also anticipates them. The light and dark cycle with the period of about 24 h is a recurring environmental change that determines the diurnal variation in food availability and safety from predators in nature. As a result, the circadian clock is evolved in most animals to align locomotor behaviors and energy metabolism with the light cue. The central circadian clock in mammals is located at the suprachiasmatic nucleus (SCN) of the hypothalamus in the brain. We here review the molecular and anatomic architecture of the central circadian clock in mammals, describe the experimental and observational evidence that suggests a critical role of the central circadian clock in shaping systemic energy metabolism, and discuss the involvement of endocrine factors, neuropeptides, and the autonomic nervous system in the metabolic functions of the central circadian clock." @default.
- W2898863223 created "2018-11-09" @default.
- W2898863223 creator A5036760608 @default.
- W2898863223 creator A5045411679 @default.
- W2898863223 creator A5055574735 @default.
- W2898863223 creator A5067506039 @default.
- W2898863223 date "2018-01-01" @default.
- W2898863223 modified "2023-10-16" @default.
- W2898863223 title "Central Circadian Clock Regulates Energy Metabolism" @default.
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