FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898866538> ?p ?o ?g. }

• W2898866538 endingPage "2964" @default.
• W2898866538 startingPage "2955" @default.
• W2898866538 abstract "Profile of inhaled levodopa and its potential in the treatment of Parkinson's disease: evidence to date Ami B Patel, Joohi Jimenez-Shahed Department of Neurology, Baylor College of Medicine, Houston, TX, USA Abstract: Inhaled levodopa is a newly emerging therapeutic option in the treatment of “off” symptoms associated with Parkinson’s disease (PD). Its mode of delivery offers more rapid absorption of levodopa and shorter onset of clinical benefit compared to oral formulations, and has been shown to be feasible for use in patients with PD experiencing worse motor function due to declining plasma levodopa levels. Clinical development of this compound is supported by preclinical, Phase I–III, long-term-safety studies and studies in special populations, including otherwise-healthy asthmatics and smokers. These investigations demonstrated that the drug is well tolerated without risk of long-term (up to 1 year) changes in pulmonary function or spirometry measures. The most common side effects among PD patients were a mild cough, upper respiratory tract infection, nausea, sputum discoloration, and dyskinesia. Inhaled levodopa offers a different administration method and side-effect profile from the currently available options for rescue therapy for Off periods in PD, though comparative studies have not been performed. The drug is presently under review by the US Food and Drug Administration. Keywords: levodopa, dry-powder inhalation, motor fluctuations, dyskinesia, spirometry" @default.
• W2898866538 created "2018-11-09" @default.
• W2898866538 creator A5015721522 @default.
• W2898866538 creator A5016009018 @default.
• W2898866538 date "2018-11-01" @default.
• W2898866538 modified "2023-09-25" @default.
• W2898866538 title "Profile of inhaled levodopa and its potential in the treatment of Parkinson&rsquo;s disease: evidence to date" @default.
• W2898866538 cites W1531988156 @default.
• W2898866538 cites W1533056363 @default.
• W2898866538 cites W1552942501 @default.
• W2898866538 cites W1973352953 @default.
• W2898866538 cites W1974860230 @default.
• W2898866538 cites W1975567689 @default.
• W2898866538 cites W1980803266 @default.
• W2898866538 cites W1984439185 @default.
• W2898866538 cites W1988284593 @default.
• W2898866538 cites W2008485195 @default.
• W2898866538 cites W2019038003 @default.
• W2898866538 cites W2034307747 @default.
• W2898866538 cites W2073449985 @default.
• W2898866538 cites W2103984901 @default.
• W2898866538 cites W2112455323 @default.
• W2898866538 cites W2117459151 @default.
• W2898866538 cites W2135323430 @default.
• W2898866538 cites W2141311399 @default.
• W2898866538 cites W2144139482 @default.
• W2898866538 cites W2145667001 @default.
• W2898866538 cites W21769058 @default.
• W2898866538 cites W2194053553 @default.
• W2898866538 cites W2275107578 @default.
• W2898866538 cites W2298300860 @default.
• W2898866538 cites W2341405122 @default.
• W2898866538 cites W2474578944 @default.
• W2898866538 cites W2496559268 @default.
• W2898866538 cites W2530995389 @default.
• W2898866538 cites W2770852789 @default.
• W2898866538 cites W2797709183 @default.
• W2898866538 cites W2886487705 @default.
• W2898866538 cites W2887083607 @default.
• W2898866538 doi "https://doi.org/10.2147/ndt.s147633" @default.
• W2898866538 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6220433" @default.
• W2898866538 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30464480" @default.
• W2898866538 hasPublicationYear "2018" @default.
• W2898866538 type Work @default.
• W2898866538 sameAs 2898866538 @default.
• W2898866538 citedByCount "21" @default.
• W2898866538 countsByYear W28988665382015 @default.
• W2898866538 countsByYear W28988665382019 @default.
• W2898866538 countsByYear W28988665382020 @default.
• W2898866538 countsByYear W28988665382021 @default.
• W2898866538 countsByYear W28988665382022 @default.
• W2898866538 countsByYear W28988665382023 @default.
• W2898866538 crossrefType "journal-article" @default.
• W2898866538 hasAuthorship W2898866538A5015721522 @default.
• W2898866538 hasAuthorship W2898866538A5016009018 @default.
• W2898866538 hasBestOaLocation W28988665381 @default.
• W2898866538 hasConcept C126322002 @default.
• W2898866538 hasConcept C177713679 @default.
• W2898866538 hasConcept C2776042228 @default.
• W2898866538 hasConcept C2776954882 @default.
• W2898866538 hasConcept C2779134260 @default.
• W2898866538 hasConcept C2779734285 @default.
• W2898866538 hasConcept C2779998641 @default.
• W2898866538 hasConcept C2780035454 @default.
• W2898866538 hasConcept C2780304432 @default.
• W2898866538 hasConcept C2780333948 @default.
• W2898866538 hasConcept C2780405171 @default.
• W2898866538 hasConcept C2780580376 @default.
• W2898866538 hasConcept C42219234 @default.
• W2898866538 hasConcept C71924100 @default.
• W2898866538 hasConcept C98274493 @default.
• W2898866538 hasConceptScore W2898866538C126322002 @default.
• W2898866538 hasConceptScore W2898866538C177713679 @default.
• W2898866538 hasConceptScore W2898866538C2776042228 @default.
• W2898866538 hasConceptScore W2898866538C2776954882 @default.
• W2898866538 hasConceptScore W2898866538C2779134260 @default.
• W2898866538 hasConceptScore W2898866538C2779734285 @default.
• W2898866538 hasConceptScore W2898866538C2779998641 @default.
• W2898866538 hasConceptScore W2898866538C2780035454 @default.
• W2898866538 hasConceptScore W2898866538C2780304432 @default.
• W2898866538 hasConceptScore W2898866538C2780333948 @default.
• W2898866538 hasConceptScore W2898866538C2780405171 @default.
• W2898866538 hasConceptScore W2898866538C2780580376 @default.
• W2898866538 hasConceptScore W2898866538C42219234 @default.
• W2898866538 hasConceptScore W2898866538C71924100 @default.
• W2898866538 hasConceptScore W2898866538C98274493 @default.
• W2898866538 hasLocation W28988665381 @default.
• W2898866538 hasLocation W28988665382 @default.
• W2898866538 hasLocation W28988665383 @default.
• W2898866538 hasLocation W28988665384 @default.
• W2898866538 hasOpenAccess W2898866538 @default.
• W2898866538 hasPrimaryLocation W28988665381 @default.
• W2898866538 hasRelatedWork W1522308250 @default.
• W2898866538 hasRelatedWork W1900332198 @default.
• W2898866538 hasRelatedWork W2014733789 @default.
• W2898866538 hasRelatedWork W2019422441 @default.
• W2898866538 hasRelatedWork W2231018250 @default.
• W2898866538 hasRelatedWork W2461633631 @default.

• next