Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898874382> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2898874382 endingPage "46" @default.
- W2898874382 startingPage "43" @default.
- W2898874382 abstract "Fournier's gangrene is an infective necrotising fasciitis of the external genitalia and perineum associated with significant morbidity and mortality. The factors associated with non survival have been described but are not universally accepted. The identification of prognostic factors remains critical to improve outcomes.To determine the hospital based mortality and factors associated with non-survival among subjects with a clinical diagnosis of Fournier's gangrene.A prospective hospital based observational study on 51patients with a clinical diagnosis of Fournier's gangrene over a 2-year period. A comparison was made between survivors and non-survivors to establish prognostic factors associated with non survival.The disease related hospital mortality was 27% (14/51). The mean age of the 51, all male patients was 47 years. An older age was significantly associated with non-survival (p=0.02). The presence of renal dysfunction (p=0.001), severe sepsis (p=0.000), delay in surgical debridment (p=0.04), urogenital source of infection (p=0.01), a body surface area involvement of greater than 5% (p=0.006), abdominal wall involvement (p=0.02) on admission were significant factors associated with mortality. The presence of either HIV infection or diabetes mellitus was not a prognostic indicator of mortality. The clinical and biochemical parameters on admission associated with non survival were a high respiratory rate (p=0.03), a low hemoglobin(p=0.0001), an elevated blood urea nitrogen (p=0.005) and creatinine (p=0.01). Multivariate logistic regression analysis did not show any independent factors associated with non survival.Fournier's gangrene remains a fatal condition with a hospital mortality of 27%. Prognostic factors for non survival include an advanced age, a urogenital source of infection, abdominal involvement, severe sepsis and renal dysfunction." @default.
- W2898874382 created "2018-11-09" @default.
- W2898874382 creator A5023852826 @default.
- W2898874382 creator A5039819959 @default.
- W2898874382 creator A5047285673 @default.
- W2898874382 date "2018-01-01" @default.
- W2898874382 modified "2023-10-14" @default.
- W2898874382 title "Fournier's gangrene: outcome analysis and prognostic factors" @default.
- W2898874382 cites W1543105914 @default.
- W2898874382 cites W1911573012 @default.
- W2898874382 cites W1974329515 @default.
- W2898874382 cites W1975704598 @default.
- W2898874382 cites W1982166141 @default.
- W2898874382 cites W2017701762 @default.
- W2898874382 cites W2031657251 @default.
- W2898874382 cites W2039562262 @default.
- W2898874382 cites W2062812969 @default.
- W2898874382 cites W2083098473 @default.
- W2898874382 cites W2131183591 @default.
- W2898874382 doi "https://doi.org/10.17159/2078-5151/2018/v56n3a2409" @default.
- W2898874382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30264942" @default.
- W2898874382 hasPublicationYear "2018" @default.
- W2898874382 type Work @default.
- W2898874382 sameAs 2898874382 @default.
- W2898874382 citedByCount "5" @default.
- W2898874382 countsByYear W28988743822019 @default.
- W2898874382 countsByYear W28988743822021 @default.
- W2898874382 countsByYear W28988743822023 @default.
- W2898874382 crossrefType "journal-article" @default.
- W2898874382 hasAuthorship W2898874382A5023852826 @default.
- W2898874382 hasAuthorship W2898874382A5039819959 @default.
- W2898874382 hasAuthorship W2898874382A5047285673 @default.
- W2898874382 hasBestOaLocation W28988743821 @default.
- W2898874382 hasConcept C126322002 @default.
- W2898874382 hasConcept C133507102 @default.
- W2898874382 hasConcept C134018914 @default.
- W2898874382 hasConcept C141071460 @default.
- W2898874382 hasConcept C179755657 @default.
- W2898874382 hasConcept C2776282561 @default.
- W2898874382 hasConcept C2776283816 @default.
- W2898874382 hasConcept C2776626339 @default.
- W2898874382 hasConcept C2777217379 @default.
- W2898874382 hasConcept C2778384902 @default.
- W2898874382 hasConcept C2780306776 @default.
- W2898874382 hasConcept C2780344330 @default.
- W2898874382 hasConcept C2781163205 @default.
- W2898874382 hasConcept C555293320 @default.
- W2898874382 hasConcept C71924100 @default.
- W2898874382 hasConceptScore W2898874382C126322002 @default.
- W2898874382 hasConceptScore W2898874382C133507102 @default.
- W2898874382 hasConceptScore W2898874382C134018914 @default.
- W2898874382 hasConceptScore W2898874382C141071460 @default.
- W2898874382 hasConceptScore W2898874382C179755657 @default.
- W2898874382 hasConceptScore W2898874382C2776282561 @default.
- W2898874382 hasConceptScore W2898874382C2776283816 @default.
- W2898874382 hasConceptScore W2898874382C2776626339 @default.
- W2898874382 hasConceptScore W2898874382C2777217379 @default.
- W2898874382 hasConceptScore W2898874382C2778384902 @default.
- W2898874382 hasConceptScore W2898874382C2780306776 @default.
- W2898874382 hasConceptScore W2898874382C2780344330 @default.
- W2898874382 hasConceptScore W2898874382C2781163205 @default.
- W2898874382 hasConceptScore W2898874382C555293320 @default.
- W2898874382 hasConceptScore W2898874382C71924100 @default.
- W2898874382 hasIssue "3" @default.
- W2898874382 hasLocation W28988743821 @default.
- W2898874382 hasLocation W28988743822 @default.
- W2898874382 hasOpenAccess W2898874382 @default.
- W2898874382 hasPrimaryLocation W28988743821 @default.
- W2898874382 hasRelatedWork W1994474922 @default.
- W2898874382 hasRelatedWork W2030770787 @default.
- W2898874382 hasRelatedWork W2086405135 @default.
- W2898874382 hasRelatedWork W2163193808 @default.
- W2898874382 hasRelatedWork W2237689628 @default.
- W2898874382 hasRelatedWork W2386510333 @default.
- W2898874382 hasRelatedWork W2495443309 @default.
- W2898874382 hasRelatedWork W2509356343 @default.
- W2898874382 hasRelatedWork W3039003996 @default.
- W2898874382 hasRelatedWork W4282972161 @default.
- W2898874382 hasVolume "56" @default.
- W2898874382 isParatext "false" @default.
- W2898874382 isRetracted "false" @default.
- W2898874382 magId "2898874382" @default.
- W2898874382 workType "article" @default.