Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898888802> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2898888802 abstract "Introduction. Attention deficit hyperactivity disorder (ADHD) is one of the most common neuropsychiatric conditions in childhood and a multifactorial condition attributable to genetic and/or environmental influence. Allelic variants in the serotonin transporter gene (SLC6A4) have been associated to lower transcriptional efficiency, changes in serotonin concentration in several brain regions, and ADHD development. Objective. To identify the association between the SLC6A4 alleles and ADHD diagnosis and risk factor phenotypes in children from a Mexican mestizo population. Method. In this study, 134 unrelated children were included and evaluated for ADHD, genotypification for the 5HTTLPR polymorphism, and identification of multiple phenotypes from their clinical records and family background for association analysis. Results. The following distribution of genotypes was observed: 23% SS, 49% SL, and 28% LL. From the phenotypes evaluated in the present study, gestational diabetes mellitus (p = .045), history of epilepsy (p = .047), and parental substance abuse (p = .033) showed an association with ADHD development in regression analysis along with the S variant. Discussion and conclusion. Results suggest that interaction of the S allele and some of the phenotypes analyzed may play a relevant role in the development of ADHD in the studied population." @default.
- W2898888802 created "2018-11-09" @default.
- W2898888802 creator A5008904197 @default.
- W2898888802 creator A5019594677 @default.
- W2898888802 creator A5045017483 @default.
- W2898888802 creator A5046037411 @default.
- W2898888802 creator A5046593781 @default.
- W2898888802 creator A5049797536 @default.
- W2898888802 creator A5054273001 @default.
- W2898888802 creator A5072379619 @default.
- W2898888802 creator A5078597840 @default.
- W2898888802 creator A5084122333 @default.
- W2898888802 date "2018-10-25" @default.
- W2898888802 modified "2023-10-14" @default.
- W2898888802 title "Association of the SLC6A4 gene 5HTTLPR polymorphism and ADHD with epilepsy, gestational diabetes, and parental substance abuse in Mexican mestizo children" @default.
- W2898888802 doi "https://doi.org/10.17711/sm.0185-3325.2018.033" @default.
- W2898888802 hasPublicationYear "2018" @default.
- W2898888802 type Work @default.
- W2898888802 sameAs 2898888802 @default.
- W2898888802 citedByCount "0" @default.
- W2898888802 crossrefType "journal-article" @default.
- W2898888802 hasAuthorship W2898888802A5008904197 @default.
- W2898888802 hasAuthorship W2898888802A5019594677 @default.
- W2898888802 hasAuthorship W2898888802A5045017483 @default.
- W2898888802 hasAuthorship W2898888802A5046037411 @default.
- W2898888802 hasAuthorship W2898888802A5046593781 @default.
- W2898888802 hasAuthorship W2898888802A5049797536 @default.
- W2898888802 hasAuthorship W2898888802A5054273001 @default.
- W2898888802 hasAuthorship W2898888802A5072379619 @default.
- W2898888802 hasAuthorship W2898888802A5078597840 @default.
- W2898888802 hasAuthorship W2898888802A5084122333 @default.
- W2898888802 hasBestOaLocation W28988888021 @default.
- W2898888802 hasConcept C104317684 @default.
- W2898888802 hasConcept C118552586 @default.
- W2898888802 hasConcept C135763542 @default.
- W2898888802 hasConcept C149737253 @default.
- W2898888802 hasConcept C15744967 @default.
- W2898888802 hasConcept C180754005 @default.
- W2898888802 hasConcept C2778186239 @default.
- W2898888802 hasConcept C2778897192 @default.
- W2898888802 hasConcept C2780783007 @default.
- W2898888802 hasConcept C2908647359 @default.
- W2898888802 hasConcept C54355233 @default.
- W2898888802 hasConcept C71924100 @default.
- W2898888802 hasConcept C86803240 @default.
- W2898888802 hasConcept C99454951 @default.
- W2898888802 hasConceptScore W2898888802C104317684 @default.
- W2898888802 hasConceptScore W2898888802C118552586 @default.
- W2898888802 hasConceptScore W2898888802C135763542 @default.
- W2898888802 hasConceptScore W2898888802C149737253 @default.
- W2898888802 hasConceptScore W2898888802C15744967 @default.
- W2898888802 hasConceptScore W2898888802C180754005 @default.
- W2898888802 hasConceptScore W2898888802C2778186239 @default.
- W2898888802 hasConceptScore W2898888802C2778897192 @default.
- W2898888802 hasConceptScore W2898888802C2780783007 @default.
- W2898888802 hasConceptScore W2898888802C2908647359 @default.
- W2898888802 hasConceptScore W2898888802C54355233 @default.
- W2898888802 hasConceptScore W2898888802C71924100 @default.
- W2898888802 hasConceptScore W2898888802C86803240 @default.
- W2898888802 hasConceptScore W2898888802C99454951 @default.
- W2898888802 hasLocation W28988888021 @default.
- W2898888802 hasOpenAccess W2898888802 @default.
- W2898888802 hasPrimaryLocation W28988888021 @default.
- W2898888802 hasRelatedWork W1977949510 @default.
- W2898888802 hasRelatedWork W1992500518 @default.
- W2898888802 hasRelatedWork W2003240462 @default.
- W2898888802 hasRelatedWork W2009064496 @default.
- W2898888802 hasRelatedWork W2021075292 @default.
- W2898888802 hasRelatedWork W2028337193 @default.
- W2898888802 hasRelatedWork W2043809050 @default.
- W2898888802 hasRelatedWork W2079148281 @default.
- W2898888802 hasRelatedWork W2399910837 @default.
- W2898888802 hasRelatedWork W290528026 @default.
- W2898888802 isParatext "false" @default.
- W2898888802 isRetracted "false" @default.
- W2898888802 magId "2898888802" @default.
- W2898888802 workType "article" @default.