Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898891945> ?p ?o ?g. }
- W2898891945 endingPage "179" @default.
- W2898891945 startingPage "174" @default.
- W2898891945 abstract "Metabolic dysfunctions in patients with bipolar disorder (BD) are critical factors that interfere with outcome, but only one study evaluated the influence of glucose dysmetabolism on the response to treatment with lithium. We aimed to investigate the potential impact of glucose metabolic status on clinical characteristics of BD patients and their response to treatment with different mood stabilizers in monotherapy or in combination. 45 BD patients with insulin resistance (IR) or type 2 diabetes mellitus (DM2) and 46 patients with normal glucose metabolism, treated with mood stabilizers for at least one year were assessed by diagnostic and rating instruments. Their clinical characteristics were compared and an ordinal logistic regression model was adopted to identify possible predictors of response to mood stabilizer treatments. Compared to patients with normal glucose metabolism, BD patients with impaired glucose metabolism showed a worse clinical presentation of their psychiatric illness and a worse response to mood stabilizers. Ordinal logistic regression analysis evidenced that impaired glucose metabolism was the only predictor of poor response to mood stabilizers (OR 4.3; 95% CI: 1.7–11.1; p < 0.002). Cross-sectional design and the relatively small sample size, are the main limitations of our study. Our findings expand literature data suggesting that BD patients with impaired glucose metabolism are at a greater risk of not responding to lithium as well as to different mood stabilizer treatments." @default.
- W2898891945 created "2018-11-09" @default.
- W2898891945 creator A5020615555 @default.
- W2898891945 creator A5030513293 @default.
- W2898891945 creator A5034202828 @default.
- W2898891945 creator A5041866909 @default.
- W2898891945 creator A5044712665 @default.
- W2898891945 creator A5053643962 @default.
- W2898891945 creator A5065260064 @default.
- W2898891945 date "2019-02-01" @default.
- W2898891945 modified "2023-10-14" @default.
- W2898891945 title "Impaired glucose metabolism in bipolar patients and response to mood stabilizer treatments" @default.
- W2898891945 cites W1757453904 @default.
- W2898891945 cites W1784375948 @default.
- W2898891945 cites W1908612571 @default.
- W2898891945 cites W1963650892 @default.
- W2898891945 cites W1975483564 @default.
- W2898891945 cites W1976681359 @default.
- W2898891945 cites W1979993283 @default.
- W2898891945 cites W1983200719 @default.
- W2898891945 cites W1989190407 @default.
- W2898891945 cites W2011578113 @default.
- W2898891945 cites W2013240652 @default.
- W2898891945 cites W2015594426 @default.
- W2898891945 cites W2019823288 @default.
- W2898891945 cites W2030034545 @default.
- W2898891945 cites W2034753731 @default.
- W2898891945 cites W2035085197 @default.
- W2898891945 cites W2040181124 @default.
- W2898891945 cites W2052670093 @default.
- W2898891945 cites W2055786778 @default.
- W2898891945 cites W2058138221 @default.
- W2898891945 cites W2062589057 @default.
- W2898891945 cites W2063598898 @default.
- W2898891945 cites W2072521109 @default.
- W2898891945 cites W2076403167 @default.
- W2898891945 cites W2079384709 @default.
- W2898891945 cites W2082394860 @default.
- W2898891945 cites W2090895117 @default.
- W2898891945 cites W2091044076 @default.
- W2898891945 cites W2091344416 @default.
- W2898891945 cites W21018241 @default.
- W2898891945 cites W2106707179 @default.
- W2898891945 cites W2110803880 @default.
- W2898891945 cites W2115281234 @default.
- W2898891945 cites W2117052065 @default.
- W2898891945 cites W2121408857 @default.
- W2898891945 cites W2134773980 @default.
- W2898891945 cites W2135169462 @default.
- W2898891945 cites W2144929494 @default.
- W2898891945 cites W2153250061 @default.
- W2898891945 cites W2155180926 @default.
- W2898891945 cites W2157917450 @default.
- W2898891945 cites W2160234571 @default.
- W2898891945 cites W2161456195 @default.
- W2898891945 cites W2163224933 @default.
- W2898891945 cites W2165435051 @default.
- W2898891945 cites W2167659819 @default.
- W2898891945 cites W2205018829 @default.
- W2898891945 cites W2237023802 @default.
- W2898891945 cites W2577734910 @default.
- W2898891945 cites W2865060325 @default.
- W2898891945 cites W4234324384 @default.
- W2898891945 cites W88441925 @default.
- W2898891945 doi "https://doi.org/10.1016/j.jad.2018.10.360" @default.
- W2898891945 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30391773" @default.
- W2898891945 hasPublicationYear "2019" @default.
- W2898891945 type Work @default.
- W2898891945 sameAs 2898891945 @default.
- W2898891945 citedByCount "23" @default.
- W2898891945 countsByYear W28988919452019 @default.
- W2898891945 countsByYear W28988919452020 @default.
- W2898891945 countsByYear W28988919452021 @default.
- W2898891945 countsByYear W28988919452022 @default.
- W2898891945 countsByYear W28988919452023 @default.
- W2898891945 crossrefType "journal-article" @default.
- W2898891945 hasAuthorship W2898891945A5020615555 @default.
- W2898891945 hasAuthorship W2898891945A5030513293 @default.
- W2898891945 hasAuthorship W2898891945A5034202828 @default.
- W2898891945 hasAuthorship W2898891945A5041866909 @default.
- W2898891945 hasAuthorship W2898891945A5044712665 @default.
- W2898891945 hasAuthorship W2898891945A5053643962 @default.
- W2898891945 hasAuthorship W2898891945A5065260064 @default.
- W2898891945 hasConcept C118552586 @default.
- W2898891945 hasConcept C126322002 @default.
- W2898891945 hasConcept C134018914 @default.
- W2898891945 hasConcept C151956035 @default.
- W2898891945 hasConcept C15744967 @default.
- W2898891945 hasConcept C17093226 @default.
- W2898891945 hasConcept C2776174506 @default.
- W2898891945 hasConcept C2780550438 @default.
- W2898891945 hasConcept C2780733359 @default.
- W2898891945 hasConcept C555293320 @default.
- W2898891945 hasConcept C71924100 @default.
- W2898891945 hasConceptScore W2898891945C118552586 @default.
- W2898891945 hasConceptScore W2898891945C126322002 @default.
- W2898891945 hasConceptScore W2898891945C134018914 @default.
- W2898891945 hasConceptScore W2898891945C151956035 @default.