FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898893836> ?p ?o ?g. }

• W2898893836 endingPage "1247" @default.
• W2898893836 startingPage "1241" @default.
• W2898893836 abstract "BackgroundExtracorporeal circuit coating has been shown to improve coagulation derangements during pediatric cardiopulmonary bypass (CPB). This study compared platelet function and hemostasis activation in pediatric cardiac surgery conducted with nonheparin coating (Balance; Medtronic, Minneapolis, MN) versus heparin-based coating (Carmeda; Medtronic) circuits.MethodsA prospective, randomized, double-center trial was conducted in children older than 1 month undergoing congenital heart disease treatment. Blood samples were collected at baseline (T0), 15 minutes after the start of CPB (T1), and 15 minutes (T2) and 1 hour after the conclusion of CPB (T3). The primary end point of the study was to detect potential differences in β-thromboglobulin levels between the two groups at T2. Other coagulation and platelet function indicators were analyzed as secondary end points.ResultsThe concentration of β-thromboglobulin increased significantly at T2 in both groups. However, there was no significant difference between the groups across all time points. There was no difference in the secondary end points between the groups.ConclusionsThe two circuits showed similar biological effects on platelet function and coagulation. This observation may be useful in optimizing the conduct of CPB and in rationalizing its cost for the treatment of congenital heart disease. Extracorporeal circuit coating has been shown to improve coagulation derangements during pediatric cardiopulmonary bypass (CPB). This study compared platelet function and hemostasis activation in pediatric cardiac surgery conducted with nonheparin coating (Balance; Medtronic, Minneapolis, MN) versus heparin-based coating (Carmeda; Medtronic) circuits. A prospective, randomized, double-center trial was conducted in children older than 1 month undergoing congenital heart disease treatment. Blood samples were collected at baseline (T0), 15 minutes after the start of CPB (T1), and 15 minutes (T2) and 1 hour after the conclusion of CPB (T3). The primary end point of the study was to detect potential differences in β-thromboglobulin levels between the two groups at T2. Other coagulation and platelet function indicators were analyzed as secondary end points. The concentration of β-thromboglobulin increased significantly at T2 in both groups. However, there was no significant difference between the groups across all time points. There was no difference in the secondary end points between the groups. The two circuits showed similar biological effects on platelet function and coagulation. This observation may be useful in optimizing the conduct of CPB and in rationalizing its cost for the treatment of congenital heart disease." @default.
• W2898893836 created "2018-11-09" @default.
• W2898893836 creator A5017170587 @default.
• W2898893836 creator A5039132008 @default.
• W2898893836 creator A5046899993 @default.
• W2898893836 creator A5057538449 @default.
• W2898893836 creator A5058195052 @default.
• W2898893836 creator A5060923209 @default.
• W2898893836 creator A5072476279 @default.
• W2898893836 creator A5074314846 @default.
• W2898893836 creator A5075939022 @default.
• W2898893836 creator A5076182619 @default.
• W2898893836 creator A5085909988 @default.
• W2898893836 creator A5091694136 @default.
• W2898893836 creator A5091750119 @default.
• W2898893836 date "2019-04-01" @default.
• W2898893836 modified "2023-09-27" @default.
• W2898893836 title "Impact of Heparin- or Nonheparin-Coated Circuits on Platelet Function in Pediatric Cardiac Surgery" @default.
• W2898893836 cites W1484320290 @default.
• W2898893836 cites W1507706784 @default.
• W2898893836 cites W1979296684 @default.
• W2898893836 cites W1982517226 @default.
• W2898893836 cites W1994457704 @default.
• W2898893836 cites W2044849421 @default.
• W2898893836 cites W2045691857 @default.
• W2898893836 cites W2046532421 @default.
• W2898893836 cites W2048431363 @default.
• W2898893836 cites W2072416190 @default.
• W2898893836 cites W2092025164 @default.
• W2898893836 cites W2094487031 @default.
• W2898893836 cites W2103321447 @default.
• W2898893836 cites W2106459062 @default.
• W2898893836 cites W2106877484 @default.
• W2898893836 cites W2128519133 @default.
• W2898893836 cites W2141153377 @default.
• W2898893836 cites W2230891383 @default.
• W2898893836 cites W2318323991 @default.
• W2898893836 cites W2382014455 @default.
• W2898893836 cites W2422487272 @default.
• W2898893836 cites W4385402972 @default.
• W2898893836 doi "https://doi.org/10.1016/j.athoracsur.2018.09.032" @default.
• W2898893836 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30395857" @default.
• W2898893836 hasPublicationYear "2019" @default.
• W2898893836 type Work @default.
• W2898893836 sameAs 2898893836 @default.
• W2898893836 citedByCount "2" @default.
• W2898893836 countsByYear W28988938362020 @default.
• W2898893836 countsByYear W28988938362021 @default.
• W2898893836 crossrefType "journal-article" @default.
• W2898893836 hasAuthorship W2898893836A5017170587 @default.
• W2898893836 hasAuthorship W2898893836A5039132008 @default.
• W2898893836 hasAuthorship W2898893836A5046899993 @default.
• W2898893836 hasAuthorship W2898893836A5057538449 @default.
• W2898893836 hasAuthorship W2898893836A5058195052 @default.
• W2898893836 hasAuthorship W2898893836A5060923209 @default.
• W2898893836 hasAuthorship W2898893836A5072476279 @default.
• W2898893836 hasAuthorship W2898893836A5074314846 @default.
• W2898893836 hasAuthorship W2898893836A5075939022 @default.
• W2898893836 hasAuthorship W2898893836A5076182619 @default.
• W2898893836 hasAuthorship W2898893836A5085909988 @default.
• W2898893836 hasAuthorship W2898893836A5091694136 @default.
• W2898893836 hasAuthorship W2898893836A5091750119 @default.
• W2898893836 hasBestOaLocation W28988938361 @default.
• W2898893836 hasConcept C111566952 @default.
• W2898893836 hasConcept C126322002 @default.
• W2898893836 hasConcept C141071460 @default.
• W2898893836 hasConcept C159973064 @default.
• W2898893836 hasConcept C164705383 @default.
• W2898893836 hasConcept C188816634 @default.
• W2898893836 hasConcept C2777557582 @default.
• W2898893836 hasConcept C2778198053 @default.
• W2898893836 hasConcept C2778382381 @default.
• W2898893836 hasConcept C2778589496 @default.
• W2898893836 hasConcept C2778789114 @default.
• W2898893836 hasConcept C2778881276 @default.
• W2898893836 hasConcept C2779915274 @default.
• W2898893836 hasConcept C2780074459 @default.
• W2898893836 hasConcept C42219234 @default.
• W2898893836 hasConcept C71924100 @default.
• W2898893836 hasConcept C89560881 @default.
• W2898893836 hasConceptScore W2898893836C111566952 @default.
• W2898893836 hasConceptScore W2898893836C126322002 @default.
• W2898893836 hasConceptScore W2898893836C141071460 @default.
• W2898893836 hasConceptScore W2898893836C159973064 @default.
• W2898893836 hasConceptScore W2898893836C164705383 @default.
• W2898893836 hasConceptScore W2898893836C188816634 @default.
• W2898893836 hasConceptScore W2898893836C2777557582 @default.
• W2898893836 hasConceptScore W2898893836C2778198053 @default.
• W2898893836 hasConceptScore W2898893836C2778382381 @default.
• W2898893836 hasConceptScore W2898893836C2778589496 @default.
• W2898893836 hasConceptScore W2898893836C2778789114 @default.
• W2898893836 hasConceptScore W2898893836C2778881276 @default.
• W2898893836 hasConceptScore W2898893836C2779915274 @default.
• W2898893836 hasConceptScore W2898893836C2780074459 @default.
• W2898893836 hasConceptScore W2898893836C42219234 @default.
• W2898893836 hasConceptScore W2898893836C71924100 @default.
• W2898893836 hasConceptScore W2898893836C89560881 @default.
• W2898893836 hasIssue "4" @default.

• next