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- W2898899048 abstract "Mammary tumors are the second most common neoplasia in dogs. Due to the high similarity of canine mammary tumors (CMT) to human breast cancers (HBC), human biomarkers of HBC are also detectable in cases of CMT. The evaluation of biomarkers enables clinical diagnoses, treatment options and prognosis for bitches suffering from this disease. The aim of this article is to give a short summary of the biomarkers of CMT based on current literature. Very promising biomarkers are miRNAs, cancer stem cells, and circulating tumor cells, as well as mutations of the breast cancer 1 gene (BRCA1) and breast cancer 2 gene (BRCA2). Until now, the most studied and reliable biomarkers of CMT have remained antigen Ki-67 (Ki-67), endothelial growth factor receptor, human epidermal growth factor receptor 2 (HER-2), estrogen receptor, progesterone receptor and cyclooxygenase 1 (COX-2), which can be detected in both serum and tissue samples using different molecular methods. However, carcinoembryonic antigen and cancer antigen 15-3 (CA 15-3), while poorly studied, seem to be good biomarkers, especially for the early detection and prognosis of CMT. We will also mention the following: proliferative cell nuclear antigen, tumor protein p53 (p53), E-cadherin, vascular endothelial growth factor, microRNAs, cancer stem cells and circulating tumor cells, which can also be useful biomarkers. Although many studies have been conducted so far, the estimation of biomarkers in cases of CMT is still not a common practice, and more detailed research should be done." @default.
- W2898899048 created "2018-11-09" @default.
- W2898899048 creator A5000157763 @default.
- W2898899048 creator A5019106397 @default.
- W2898899048 creator A5050966538 @default.
- W2898899048 creator A5063074729 @default.
- W2898899048 creator A5080748231 @default.
- W2898899048 creator A5082528621 @default.
- W2898899048 date "2018-10-29" @default.
- W2898899048 modified "2023-10-16" @default.
- W2898899048 title "Current biomarkers of canine mammary tumors" @default.
- W2898899048 cites W1033623824 @default.
- W2898899048 cites W1480599264 @default.
- W2898899048 cites W1537625504 @default.
- W2898899048 cites W1584094465 @default.
- W2898899048 cites W1764185400 @default.
- W2898899048 cites W1837627531 @default.
- W2898899048 cites W1846727966 @default.
- W2898899048 cites W1863700672 @default.
- W2898899048 cites W1896237858 @default.
- W2898899048 cites W1951385890 @default.
- W2898899048 cites W1966291916 @default.
- W2898899048 cites W1967186092 @default.
- W2898899048 cites W1968251903 @default.
- W2898899048 cites W1970085289 @default.
- W2898899048 cites W1981480156 @default.
- W2898899048 cites W1981635051 @default.
- W2898899048 cites W1982369249 @default.
- W2898899048 cites W1984460306 @default.
- W2898899048 cites W1985587984 @default.
- W2898899048 cites W1988055795 @default.
- W2898899048 cites W1989108196 @default.
- W2898899048 cites W1992894225 @default.
- W2898899048 cites W1997307197 @default.
- W2898899048 cites W1998369376 @default.
- W2898899048 cites W1998779259 @default.
- W2898899048 cites W2002001086 @default.
- W2898899048 cites W2003336662 @default.
- W2898899048 cites W2005855275 @default.
- W2898899048 cites W2007561489 @default.
- W2898899048 cites W2010121223 @default.
- W2898899048 cites W2010419462 @default.
- W2898899048 cites W2012213678 @default.
- W2898899048 cites W2013650568 @default.
- W2898899048 cites W2019739286 @default.
- W2898899048 cites W2022989929 @default.
- W2898899048 cites W2023926251 @default.
- W2898899048 cites W2029895840 @default.
- W2898899048 cites W2030410920 @default.
- W2898899048 cites W2031257280 @default.
- W2898899048 cites W2032563527 @default.
- W2898899048 cites W2034878249 @default.
- W2898899048 cites W2035224878 @default.
- W2898899048 cites W2037265545 @default.
- W2898899048 cites W2039189271 @default.
- W2898899048 cites W2043916741 @default.
- W2898899048 cites W2044071579 @default.
- W2898899048 cites W2044331420 @default.
- W2898899048 cites W2045155957 @default.
- W2898899048 cites W2045885767 @default.
- W2898899048 cites W2047220591 @default.
- W2898899048 cites W2048954419 @default.
- W2898899048 cites W2049602806 @default.
- W2898899048 cites W2051479506 @default.
- W2898899048 cites W2053059448 @default.
- W2898899048 cites W2054248496 @default.
- W2898899048 cites W2055440803 @default.
- W2898899048 cites W2062687357 @default.
- W2898899048 cites W2063565006 @default.
- W2898899048 cites W2066747853 @default.
- W2898899048 cites W2066851912 @default.
- W2898899048 cites W2066882106 @default.
- W2898899048 cites W2067271039 @default.
- W2898899048 cites W2068331023 @default.
- W2898899048 cites W2080489428 @default.
- W2898899048 cites W2081464023 @default.
- W2898899048 cites W2082349091 @default.
- W2898899048 cites W2087925052 @default.
- W2898899048 cites W2089136106 @default.
- W2898899048 cites W2092132834 @default.
- W2898899048 cites W2103161235 @default.
- W2898899048 cites W2104322481 @default.
- W2898899048 cites W2106291858 @default.
- W2898899048 cites W2109322526 @default.
- W2898899048 cites W2115611831 @default.
- W2898899048 cites W2117088031 @default.
- W2898899048 cites W2118396902 @default.
- W2898899048 cites W2119683373 @default.
- W2898899048 cites W2122197597 @default.
- W2898899048 cites W2124391385 @default.
- W2898899048 cites W2128571346 @default.
- W2898899048 cites W2128966132 @default.
- W2898899048 cites W2131654975 @default.
- W2898899048 cites W2131733585 @default.
- W2898899048 cites W2133228003 @default.
- W2898899048 cites W2144104692 @default.
- W2898899048 cites W2145178265 @default.
- W2898899048 cites W2147796253 @default.
- W2898899048 cites W2149204845 @default.
- W2898899048 cites W2152234318 @default.