FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2898971565> ?p ?o ?g. }

• W2898971565 endingPage "7031" @default.
• W2898971565 startingPage "7019" @default.
• W2898971565 abstract "For effective bone regeneration, it is necessary to implant a biocompatible scaffold that is capable of inducing cell growth and continuous osteogenic stimulation at the defected site. Here, we suggest an injectable hydrogel system using enzymatic cross-linkable gelatin (Gel) and functionalized gold nanoparticles (GNPs).In this work, tyramine (Ty) was synthesized on the gelatin backbone (Gel-Ty) to enable a phenol crosslinking reaction with horseradish peroxidase (HRP). N-acetyl cysteine (NAC) was attached to the GNPs surface (G-NAC) for promoting osteodifferentiation.The Gel-Ty hydrogels containing G-NAC (Gel-Ty/G-NAC) had suitable mechanical strength and biocompatibility to embed and support the growth of human adipose derived stem cells (hASCs) during a proliferation test for three days. In addition, G-NAC promoted osteodifferentiation both when it was included in Gel-Ty and when it was used directly in hASCs. The osteogenic effects were demonstrated by the alkaline phosphatase (ALP) activity test.These findings indicate that the phenol crosslinking reaction is suitable for injectable hydrogels for tissue regeneration and G-NAC stimulate bone regeneration. Based on our results, we suggest that Gel-Ty/G-NAC hydrogels can serve both as a biodegradable graft material for bone defect treatment and as a good template for tissue engineering applications such as drug delivery, cell delivery, and various tissue regeneration uses." @default.
• W2898971565 created "2018-11-09" @default.
• W2898971565 creator A5002667420 @default.
• W2898971565 creator A5003512829 @default.
• W2898971565 creator A5008686359 @default.
• W2898971565 creator A5020101637 @default.
• W2898971565 creator A5020895444 @default.
• W2898971565 creator A5023826340 @default.
• W2898971565 creator A5032036122 @default.
• W2898971565 creator A5054525674 @default.
• W2898971565 creator A5066549957 @default.
• W2898971565 creator A5069119629 @default.
• W2898971565 date "2018-11-01" @default.
• W2898971565 modified "2023-10-14" @default.
• W2898971565 title "Injectable hydrogel composite containing modified gold nanoparticles: implication in bone tissue regeneration" @default.
• W2898971565 cites W1137759576 @default.
• W2898971565 cites W1532069065 @default.
• W2898971565 cites W1963555074 @default.
• W2898971565 cites W1996139557 @default.
• W2898971565 cites W2017773896 @default.
• W2898971565 cites W2019166963 @default.
• W2898971565 cites W2024359710 @default.
• W2898971565 cites W2024936019 @default.
• W2898971565 cites W2026494961 @default.
• W2898971565 cites W2033640443 @default.
• W2898971565 cites W2035377203 @default.
• W2898971565 cites W2043389835 @default.
• W2898971565 cites W2055037957 @default.
• W2898971565 cites W2055944585 @default.
• W2898971565 cites W2077228161 @default.
• W2898971565 cites W2079871805 @default.
• W2898971565 cites W2091467286 @default.
• W2898971565 cites W2126354098 @default.
• W2898971565 cites W2138714562 @default.
• W2898971565 cites W2151352042 @default.
• W2898971565 cites W2156769174 @default.
• W2898971565 cites W2159535470 @default.
• W2898971565 cites W2162048559 @default.
• W2898971565 cites W2171083652 @default.
• W2898971565 cites W2197284960 @default.
• W2898971565 cites W2259823352 @default.
• W2898971565 cites W2269774307 @default.
• W2898971565 cites W2282086245 @default.
• W2898971565 cites W2318596848 @default.
• W2898971565 cites W2319976736 @default.
• W2898971565 cites W2330402644 @default.
• W2898971565 cites W2424519491 @default.
• W2898971565 cites W2439930002 @default.
• W2898971565 cites W2520629744 @default.
• W2898971565 cites W2595369186 @default.
• W2898971565 cites W2625080994 @default.
• W2898971565 cites W2737474979 @default.
• W2898971565 cites W2750090376 @default.
• W2898971565 cites W2785348480 @default.
• W2898971565 cites W2793975661 @default.
• W2898971565 cites W2887376231 @default.
• W2898971565 cites W4211244814 @default.
• W2898971565 doi "https://doi.org/10.2147/ijn.s185715" @default.
• W2898971565 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6219106" @default.
• W2898971565 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30464456" @default.
• W2898971565 hasPublicationYear "2018" @default.
• W2898971565 type Work @default.
• W2898971565 sameAs 2898971565 @default.
• W2898971565 citedByCount "48" @default.
• W2898971565 countsByYear W28989715652019 @default.
• W2898971565 countsByYear W28989715652020 @default.
• W2898971565 countsByYear W28989715652021 @default.
• W2898971565 countsByYear W28989715652022 @default.
• W2898971565 countsByYear W28989715652023 @default.
• W2898971565 crossrefType "journal-article" @default.
• W2898971565 hasAuthorship W2898971565A5002667420 @default.
• W2898971565 hasAuthorship W2898971565A5003512829 @default.
• W2898971565 hasAuthorship W2898971565A5008686359 @default.
• W2898971565 hasAuthorship W2898971565A5020101637 @default.
• W2898971565 hasAuthorship W2898971565A5020895444 @default.
• W2898971565 hasAuthorship W2898971565A5023826340 @default.
• W2898971565 hasAuthorship W2898971565A5032036122 @default.
• W2898971565 hasAuthorship W2898971565A5054525674 @default.
• W2898971565 hasAuthorship W2898971565A5066549957 @default.
• W2898971565 hasAuthorship W2898971565A5069119629 @default.
• W2898971565 hasBestOaLocation W28989715651 @default.
• W2898971565 hasConcept C105702510 @default.
• W2898971565 hasConcept C108586683 @default.
• W2898971565 hasConcept C136229726 @default.
• W2898971565 hasConcept C160160445 @default.
• W2898971565 hasConcept C171056886 @default.
• W2898971565 hasConcept C181199279 @default.
• W2898971565 hasConcept C185592680 @default.
• W2898971565 hasConcept C188027245 @default.
• W2898971565 hasConcept C191897082 @default.
• W2898971565 hasConcept C192562407 @default.
• W2898971565 hasConcept C2777230088 @default.
• W2898971565 hasConcept C2777676563 @default.
• W2898971565 hasConcept C2778606738 @default.
• W2898971565 hasConcept C2778823387 @default.
• W2898971565 hasConcept C55493867 @default.
• W2898971565 hasConcept C71924100 @default.
• W2898971565 hasConcept C8337478 @default.

• next