Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899042155> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2899042155 endingPage "407" @default.
- W2899042155 startingPage "400" @default.
- W2899042155 abstract "To describe the utilization of vasopressors (VP) in patients enrolled in the Australasian Resuscitation In Sepsis Evaluation (ARISE) trial, and to explore the association between time to VP and 90-day mortality.The primary exposure variable was VP use after arrival in the emergency department (ED). Vasoactive agents considered as VP included: norepinephrine, epinephrine, metaraminol, or vasopressin. Time-to-event analysis, multivariable logistic regression, and propensity-matched treatment effects modeling were used to assess the association between time to VP and 90-day mortality.In total 1,102 of 1,588 patients (69%) in ARISE received VP at any point. The median [interquartile range (IQR)] time from ED presentation to commencing VP was 4.4 [2.7, 7.1] h, and 38% did so prior to central venous access. The median [IQR] volume of intravenous (i.v.) fluid administered prior to commencing VP was 3.1 [2.3, 4.3] L. Increasing age and volume of i.v. fluid therapy were associated with a lower likelihood of commencing VP early (within 4 h of ED presentation), while greater illness severity was associated with a higher likelihood, P < 0.001, respectively. In those who subsequently died within 90 days, the sub-hazard ratio (95% confidence interval) for commencing VP was 1.4 (1.20, 1.68), P < 0.001, adjusted for age, acute physiology and chronic health evaluation II score, study group, inclusion criteria, plasma lactate, i.v. fluid prior to VP, study institution, and site of infection.50% of the ARISE cohort commenced VP within 4.4 h of ED presentation, and many did so prior to central venous access. Earlier initiation of VP was associated with greater crude and adjusted 90-day mortality." @default.
- W2899042155 created "2018-11-09" @default.
- W2899042155 creator A5011216396 @default.
- W2899042155 creator A5024970050 @default.
- W2899042155 creator A5027455882 @default.
- W2899042155 creator A5039528724 @default.
- W2899042155 creator A5050466256 @default.
- W2899042155 creator A5058756896 @default.
- W2899042155 creator A5082575689 @default.
- W2899042155 date "2019-10-01" @default.
- W2899042155 modified "2023-09-26" @default.
- W2899042155 title "Incidence, Patient Characteristics, Mode of Drug Delivery, and Outcomes of Septic Shock Patients Treated With Vasopressors in the Arise Trial" @default.
- W2899042155 cites W2035705349 @default.
- W2899042155 cites W2038981426 @default.
- W2899042155 cites W2051942363 @default.
- W2899042155 cites W2059765045 @default.
- W2899042155 cites W2094088792 @default.
- W2899042155 cites W2098019283 @default.
- W2899042155 cites W2104415072 @default.
- W2899042155 cites W2127138854 @default.
- W2899042155 cites W2141138557 @default.
- W2899042155 cites W2158448358 @default.
- W2899042155 cites W2165721969 @default.
- W2899042155 cites W2280404143 @default.
- W2899042155 cites W2323894167 @default.
- W2899042155 cites W2540196600 @default.
- W2899042155 cites W2541957841 @default.
- W2899042155 cites W2580821343 @default.
- W2899042155 cites W2625233900 @default.
- W2899042155 cites W2750890118 @default.
- W2899042155 cites W2768146862 @default.
- W2899042155 cites W3045454797 @default.
- W2899042155 doi "https://doi.org/10.1097/shk.0000000000001281" @default.
- W2899042155 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30379749" @default.
- W2899042155 hasPublicationYear "2019" @default.
- W2899042155 type Work @default.
- W2899042155 sameAs 2899042155 @default.
- W2899042155 citedByCount "15" @default.
- W2899042155 countsByYear W28990421552019 @default.
- W2899042155 countsByYear W28990421552020 @default.
- W2899042155 countsByYear W28990421552021 @default.
- W2899042155 countsByYear W28990421552022 @default.
- W2899042155 countsByYear W28990421552023 @default.
- W2899042155 crossrefType "journal-article" @default.
- W2899042155 hasAuthorship W2899042155A5011216396 @default.
- W2899042155 hasAuthorship W2899042155A5024970050 @default.
- W2899042155 hasAuthorship W2899042155A5027455882 @default.
- W2899042155 hasAuthorship W2899042155A5039528724 @default.
- W2899042155 hasAuthorship W2899042155A5050466256 @default.
- W2899042155 hasAuthorship W2899042155A5058756896 @default.
- W2899042155 hasAuthorship W2899042155A5082575689 @default.
- W2899042155 hasBestOaLocation W28990421551 @default.
- W2899042155 hasConcept C118552586 @default.
- W2899042155 hasConcept C119060515 @default.
- W2899042155 hasConcept C126322002 @default.
- W2899042155 hasConcept C156957248 @default.
- W2899042155 hasConcept C194828623 @default.
- W2899042155 hasConcept C207103383 @default.
- W2899042155 hasConcept C2777628635 @default.
- W2899042155 hasConcept C2778384902 @default.
- W2899042155 hasConcept C2780724011 @default.
- W2899042155 hasConcept C42219234 @default.
- W2899042155 hasConcept C44249647 @default.
- W2899042155 hasConcept C71924100 @default.
- W2899042155 hasConceptScore W2899042155C118552586 @default.
- W2899042155 hasConceptScore W2899042155C119060515 @default.
- W2899042155 hasConceptScore W2899042155C126322002 @default.
- W2899042155 hasConceptScore W2899042155C156957248 @default.
- W2899042155 hasConceptScore W2899042155C194828623 @default.
- W2899042155 hasConceptScore W2899042155C207103383 @default.
- W2899042155 hasConceptScore W2899042155C2777628635 @default.
- W2899042155 hasConceptScore W2899042155C2778384902 @default.
- W2899042155 hasConceptScore W2899042155C2780724011 @default.
- W2899042155 hasConceptScore W2899042155C42219234 @default.
- W2899042155 hasConceptScore W2899042155C44249647 @default.
- W2899042155 hasConceptScore W2899042155C71924100 @default.
- W2899042155 hasIssue "4" @default.
- W2899042155 hasLocation W28990421551 @default.
- W2899042155 hasLocation W28990421552 @default.
- W2899042155 hasLocation W28990421553 @default.
- W2899042155 hasOpenAccess W2899042155 @default.
- W2899042155 hasPrimaryLocation W28990421551 @default.
- W2899042155 hasRelatedWork W1968802964 @default.
- W2899042155 hasRelatedWork W1985997194 @default.
- W2899042155 hasRelatedWork W2081117055 @default.
- W2899042155 hasRelatedWork W2120309060 @default.
- W2899042155 hasRelatedWork W2183670545 @default.
- W2899042155 hasRelatedWork W2916093760 @default.
- W2899042155 hasRelatedWork W3213982935 @default.
- W2899042155 hasRelatedWork W4213351724 @default.
- W2899042155 hasRelatedWork W4221096492 @default.
- W2899042155 hasRelatedWork W863975686 @default.
- W2899042155 hasVolume "52" @default.
- W2899042155 isParatext "false" @default.
- W2899042155 isRetracted "false" @default.
- W2899042155 magId "2899042155" @default.
- W2899042155 workType "article" @default.