Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899050222> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2899050222 endingPage "296" @default.
- W2899050222 startingPage "288" @default.
- W2899050222 abstract "Background and study aim: Hepato-cellular carcinoma (HCC) is a hypervascular tumor and its progression is known to be closely related to angiogenesis. Angio-poietin-2 (Ang-2) is one of the angiogenic factors that may have a diagnostic value in HCC. Alpha-fetoprotein (AFP) serum levels are used for screening for HCC with limited success. This study aimed to evaluate diagnostic value in using angio-poietin-2 as a serum marker in HCC patients.Patients and Methods: 50 patients with HCC (G1), 20 patients with liver cirrhosis (G2), and 20 healthy control persons (G3) were included in this study. Serum AFP and Ang-2 levels were measured by enzyme-linked immunosorbent assay.Results: Serum Ang-2 levels in the HCC group (1523.54±886.46 pg/ml) was highly significantly elevated as compared to those with cirrhotic liver (222.55±153.60 pg/ml) and controls (138.35±54.09 pg/ml). The Ang-2 levels were significantly different between patients with liver cirrhosis and controls. In HCC patients, the serum Ang-2 levels in patients with portal vein (PV) thrombosis (n=7, 2164.0±960.85 pg/ml) and with large HCC (>5cm in diameter) (n=17, 2017.70±903.06 pg/ml) were significantly higher than those without PV thrombosis (n=43, 1274.47±727.56 pg/ml) and with small HCC (≤5cm in diameter) (n=33, 1268.97±773.93 pg/ml), while the serum AFP levels in patients with portal vein (PV) thrombosis (961.05±1007.70 ng/ml) and with large HCC (>5cm in diameter) (1000.81±1079.57 ng/ml) were not significantly higher than those without PV thrombosis (500.24±733.07 ng/ml) and with small HCC (437.87±611.02 ng/ml).Conclusion: Combined measurement of serum AFP and Ang-2 significantly increases the sensitivity and specificity of HCC detection rather than using of AFP or Ang-2 separately." @default.
- W2899050222 created "2018-11-09" @default.
- W2899050222 creator A5010587594 @default.
- W2899050222 creator A5018647541 @default.
- W2899050222 creator A5068305465 @default.
- W2899050222 creator A5078302989 @default.
- W2899050222 creator A5086598703 @default.
- W2899050222 date "2015-12-26" @default.
- W2899050222 modified "2023-09-27" @default.
- W2899050222 title "Diagnostic Value of Serum Angiopoietin-2 in Patients with Hepatocellular Carcinoma" @default.
- W2899050222 cites W1573363574 @default.
- W2899050222 cites W184730981 @default.
- W2899050222 cites W1964322006 @default.
- W2899050222 cites W1969875009 @default.
- W2899050222 cites W1970888316 @default.
- W2899050222 cites W1976017778 @default.
- W2899050222 cites W1989727210 @default.
- W2899050222 cites W2000502243 @default.
- W2899050222 cites W2008946188 @default.
- W2899050222 cites W2008992685 @default.
- W2899050222 cites W2014718897 @default.
- W2899050222 cites W2063938081 @default.
- W2899050222 cites W2077746894 @default.
- W2899050222 cites W2077770355 @default.
- W2899050222 cites W2104166690 @default.
- W2899050222 cites W2120772189 @default.
- W2899050222 cites W2124515692 @default.
- W2899050222 cites W2144727447 @default.
- W2899050222 cites W2148436793 @default.
- W2899050222 cites W2152215024 @default.
- W2899050222 cites W2157225099 @default.
- W2899050222 cites W2158743409 @default.
- W2899050222 cites W2163486683 @default.
- W2899050222 cites W2166119177 @default.
- W2899050222 cites W2170770755 @default.
- W2899050222 cites W2324677651 @default.
- W2899050222 cites W2410470909 @default.
- W2899050222 cites W2328441816 @default.
- W2899050222 doi "https://doi.org/10.21608/aeji.2015.17850" @default.
- W2899050222 hasPublicationYear "2015" @default.
- W2899050222 type Work @default.
- W2899050222 sameAs 2899050222 @default.
- W2899050222 citedByCount "1" @default.
- W2899050222 countsByYear W28990502222022 @default.
- W2899050222 crossrefType "journal-article" @default.
- W2899050222 hasAuthorship W2899050222A5010587594 @default.
- W2899050222 hasAuthorship W2899050222A5018647541 @default.
- W2899050222 hasAuthorship W2899050222A5068305465 @default.
- W2899050222 hasAuthorship W2899050222A5078302989 @default.
- W2899050222 hasAuthorship W2899050222A5086598703 @default.
- W2899050222 hasBestOaLocation W28990502221 @default.
- W2899050222 hasConcept C105795698 @default.
- W2899050222 hasConcept C126322002 @default.
- W2899050222 hasConcept C143998085 @default.
- W2899050222 hasConcept C167734588 @default.
- W2899050222 hasConcept C2776291640 @default.
- W2899050222 hasConcept C2777025900 @default.
- W2899050222 hasConcept C2778019345 @default.
- W2899050222 hasConcept C2779094623 @default.
- W2899050222 hasConcept C2909146873 @default.
- W2899050222 hasConcept C33923547 @default.
- W2899050222 hasConcept C502942594 @default.
- W2899050222 hasConcept C71924100 @default.
- W2899050222 hasConcept C90924648 @default.
- W2899050222 hasConceptScore W2899050222C105795698 @default.
- W2899050222 hasConceptScore W2899050222C126322002 @default.
- W2899050222 hasConceptScore W2899050222C143998085 @default.
- W2899050222 hasConceptScore W2899050222C167734588 @default.
- W2899050222 hasConceptScore W2899050222C2776291640 @default.
- W2899050222 hasConceptScore W2899050222C2777025900 @default.
- W2899050222 hasConceptScore W2899050222C2778019345 @default.
- W2899050222 hasConceptScore W2899050222C2779094623 @default.
- W2899050222 hasConceptScore W2899050222C2909146873 @default.
- W2899050222 hasConceptScore W2899050222C33923547 @default.
- W2899050222 hasConceptScore W2899050222C502942594 @default.
- W2899050222 hasConceptScore W2899050222C71924100 @default.
- W2899050222 hasConceptScore W2899050222C90924648 @default.
- W2899050222 hasIssue "4" @default.
- W2899050222 hasLocation W28990502221 @default.
- W2899050222 hasOpenAccess W2899050222 @default.
- W2899050222 hasPrimaryLocation W28990502221 @default.
- W2899050222 hasRelatedWork W2302818899 @default.
- W2899050222 hasRelatedWork W2377739753 @default.
- W2899050222 hasRelatedWork W2378709228 @default.
- W2899050222 hasRelatedWork W2382367274 @default.
- W2899050222 hasRelatedWork W2892150202 @default.
- W2899050222 hasRelatedWork W3032231671 @default.
- W2899050222 hasRelatedWork W3206239442 @default.
- W2899050222 hasRelatedWork W4232617294 @default.
- W2899050222 hasRelatedWork W4235672273 @default.
- W2899050222 hasRelatedWork W4249646865 @default.
- W2899050222 hasVolume "5" @default.
- W2899050222 isParatext "false" @default.
- W2899050222 isRetracted "false" @default.
- W2899050222 magId "2899050222" @default.
- W2899050222 workType "article" @default.