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- W2899081399 abstract "Metabolic syndrome is a complex disease that is exponentially increasing in the western world, and diet is one of the possible ways to improve the metabolic status of patients. Barley beta glucans are dietary fibres that show promise for improvement cholesterol levels and postprandial glucose response, but they have been rarely investigated in human trials with concurrent focus on gut microbiota. A double-blind, placebo-controlled, randomised clinical trial was conducted with 43 volunteers with high risk for metabolic syndrome development or with diagnosed metabolic syndrome. During a four-week intervention study, participants consumed experimental bread containing 6 g of barley beta glucans or equal bread but without beta glucans. After dietary intervention, total plasma cholesterol decreased in the test group (−0.26 ± 0.54, p = 0.019), but not in the control group. Short chain fatty acids (SCFA) composition in faeces significantly changed with increase of propionic acid in test group (43.2%, p = 0.045) and with decrease of acetic acid in control group (41.8%, p = 0.011). The microbiome analysis based on Illumina paired end sequencing of 16S rRNA genes showed a decrease in microbial diversity and richness in the test group. The pre-intervention gut microbiota composition showed higher abundance of health associated Bifidobacterium spp. and Akkermansia municiphila within cholesterol-responsive group, showing that diet-induced metabolic response is possibly dependent on individual gut microbiota composition." @default.
- W2899081399 created "2018-11-09" @default.
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- W2899081399 date "2019-02-01" @default.
- W2899081399 modified "2023-10-17" @default.
- W2899081399 title "Alterations in gut microbiota composition and metabolic parameters after dietary intervention with barley beta glucans in patients with high risk for metabolic syndrome development" @default.
- W2899081399 cites W122717592 @default.
- W2899081399 cites W1570492102 @default.
- W2899081399 cites W1790787093 @default.
- W2899081399 cites W1865630485 @default.
- W2899081399 cites W1918132278 @default.
- W2899081399 cites W1946263363 @default.
- W2899081399 cites W1978709058 @default.
- W2899081399 cites W1982278487 @default.
- W2899081399 cites W1991334358 @default.
- W2899081399 cites W1998970388 @default.
- W2899081399 cites W1999867382 @default.
- W2899081399 cites W2004005147 @default.
- W2899081399 cites W2005258869 @default.
- W2899081399 cites W2008023699 @default.
- W2899081399 cites W2013354102 @default.
- W2899081399 cites W2016295589 @default.
- W2899081399 cites W2022042057 @default.
- W2899081399 cites W2031355202 @default.
- W2899081399 cites W2031611770 @default.
- W2899081399 cites W2031993040 @default.
- W2899081399 cites W2032230795 @default.
- W2899081399 cites W2033239478 @default.
- W2899081399 cites W2041994035 @default.
- W2899081399 cites W2049042274 @default.
- W2899081399 cites W2056279562 @default.
- W2899081399 cites W2057507092 @default.
- W2899081399 cites W2066543603 @default.
- W2899081399 cites W2067748751 @default.
- W2899081399 cites W2087292184 @default.
- W2899081399 cites W2088833470 @default.
- W2899081399 cites W2091771078 @default.
- W2899081399 cites W2096736123 @default.
- W2899081399 cites W2097783355 @default.
- W2899081399 cites W2098149200 @default.
- W2899081399 cites W2108718991 @default.
- W2899081399 cites W2119675235 @default.
- W2899081399 cites W2126327417 @default.
- W2899081399 cites W2129690444 @default.
- W2899081399 cites W2130717716 @default.
- W2899081399 cites W2136417551 @default.
- W2899081399 cites W2144464830 @default.
- W2899081399 cites W2147765885 @default.
- W2899081399 cites W2149515881 @default.
- W2899081399 cites W2150916966 @default.
- W2899081399 cites W2152885278 @default.
- W2899081399 cites W2153832854 @default.
- W2899081399 cites W2154774609 @default.
- W2899081399 cites W2155924614 @default.
- W2899081399 cites W2160234571 @default.
- W2899081399 cites W2161201457 @default.
- W2899081399 cites W2163983642 @default.
- W2899081399 cites W2166562121 @default.
- W2899081399 cites W2175465469 @default.
- W2899081399 cites W2179438025 @default.
- W2899081399 cites W2254321658 @default.
- W2899081399 cites W2274927794 @default.
- W2899081399 cites W2315295058 @default.
- W2899081399 cites W2321626140 @default.
- W2899081399 cites W2322019105 @default.
- W2899081399 cites W2339765445 @default.
- W2899081399 cites W2345810007 @default.
- W2899081399 cites W2468194934 @default.
- W2899081399 cites W2484230073 @default.
- W2899081399 cites W2501184989 @default.
- W2899081399 cites W2568502991 @default.
- W2899081399 cites W2582040359 @default.
- W2899081399 cites W2605052214 @default.
- W2899081399 cites W2616172798 @default.
- W2899081399 cites W2726715613 @default.
- W2899081399 cites W2761503298 @default.
- W2899081399 cites W2765813722 @default.
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- W2899081399 doi "https://doi.org/10.1016/j.anaerobe.2018.11.002" @default.
- W2899081399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30396006" @default.
- W2899081399 hasPublicationYear "2019" @default.
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