Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899165329> ?p ?o ?g. }
- W2899165329 abstract "OBJECTIVES: To investigate brainstem function in idiopathic REM sleep Behaviour Disorder (iRBD), a condition occurring as a result of a derangement of connections within brainstem structures, with a battery of Vestibular Evoked Myogenic Potentials (VEMPs), neurophysiological tools suited for the functional investigation of the brainstem. Neurophysiological data were correlated with clinical characteristics of patients. METHODS: 20 patients with iRBD and 22 healthy controls underwent cervical (cVEMP), masseter (mVEMP) and ocular (oVEMP) VEMP recording. Patients were assessed clinically according to presence of motor as well as non-motor symptoms such as constipation, depression and hyposmia. Also, they were screened for postural instability through the Berg Balance Scale (BBS). VEMPs were categorized as for increasing degrees of abnormalities, namely latency delay, amplitude reduction and absence; a VEMP score was built accordingly. RESULTS: compared with controls, iRBD had higher rates of abnormalities both in the VEMP battery (iRBD 75%, Controls 23%; p<0.01) as well as in each single VEMP (cVEMP: 45% versus 5%; mVEMP: 65% versus 13.6%; oVEMP: 50% versus 5%; p<0.01), which exhibited significantly lower amplitudes (cVEMP and oVEMP: p<0.0001; mVEMP: p=0.001) in iRBD. Within altered reflexes, absence was predominant in oVEMP (81%), amplitude reduction in mVEMP (50%) and cVEMP (70%). Severity of VEMP alterations was significantly higher in iRBD compared with controls (p<0.05 for all VEMPs), as indicated by the larger VEMP scores in the former. The oVEMP score correlated inversely with poor performances on the BBS. CONCLUSION: VEMPs unveil consistent and extensive brainstem abnormalities in iRBD patients. Further studies are warranted for testing the potential of VEMPs in the monitoring of the evolution of iRBD over time." @default.
- W2899165329 created "2018-11-09" @default.
- W2899165329 creator A5001827320 @default.
- W2899165329 creator A5021635450 @default.
- W2899165329 creator A5025975369 @default.
- W2899165329 creator A5041483680 @default.
- W2899165329 creator A5062762451 @default.
- W2899165329 creator A5089130788 @default.
- W2899165329 creator A5089716389 @default.
- W2899165329 creator A5090127237 @default.
- W2899165329 date "2018-10-29" @default.
- W2899165329 modified "2023-10-02" @default.
- W2899165329 title "Vestibular Evoked Myogenic Potentials Are Abnormal in Idiopathic REM Sleep Behavior Disorder" @default.
- W2899165329 cites W1520340241 @default.
- W2899165329 cites W1521287996 @default.
- W2899165329 cites W1569892670 @default.
- W2899165329 cites W1657459197 @default.
- W2899165329 cites W1749218709 @default.
- W2899165329 cites W1970695190 @default.
- W2899165329 cites W1972137987 @default.
- W2899165329 cites W1981804878 @default.
- W2899165329 cites W1982495693 @default.
- W2899165329 cites W1983765773 @default.
- W2899165329 cites W1984858144 @default.
- W2899165329 cites W1993621748 @default.
- W2899165329 cites W1994053206 @default.
- W2899165329 cites W1995170630 @default.
- W2899165329 cites W1999391338 @default.
- W2899165329 cites W2004820815 @default.
- W2899165329 cites W2005571588 @default.
- W2899165329 cites W2025680640 @default.
- W2899165329 cites W2030664102 @default.
- W2899165329 cites W2031139859 @default.
- W2899165329 cites W2031995010 @default.
- W2899165329 cites W2034877634 @default.
- W2899165329 cites W2035998163 @default.
- W2899165329 cites W2049515672 @default.
- W2899165329 cites W2054671920 @default.
- W2899165329 cites W2071838225 @default.
- W2899165329 cites W2073449985 @default.
- W2899165329 cites W2078440503 @default.
- W2899165329 cites W2080927201 @default.
- W2899165329 cites W2081224997 @default.
- W2899165329 cites W2086776843 @default.
- W2899165329 cites W2086934772 @default.
- W2899165329 cites W2087866471 @default.
- W2899165329 cites W2124966970 @default.
- W2899165329 cites W2125890869 @default.
- W2899165329 cites W2129181278 @default.
- W2899165329 cites W2142278096 @default.
- W2899165329 cites W2147757468 @default.
- W2899165329 cites W2156993956 @default.
- W2899165329 cites W2157964430 @default.
- W2899165329 cites W2162234212 @default.
- W2899165329 cites W2371311871 @default.
- W2899165329 cites W2391723593 @default.
- W2899165329 cites W2776253469 @default.
- W2899165329 cites W2887418517 @default.
- W2899165329 cites W65435227 @default.
- W2899165329 doi "https://doi.org/10.3389/fneur.2018.00911" @default.
- W2899165329 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6215837" @default.
- W2899165329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30420831" @default.
- W2899165329 hasPublicationYear "2018" @default.
- W2899165329 type Work @default.
- W2899165329 sameAs 2899165329 @default.
- W2899165329 citedByCount "13" @default.
- W2899165329 countsByYear W28991653292019 @default.
- W2899165329 countsByYear W28991653292020 @default.
- W2899165329 countsByYear W28991653292021 @default.
- W2899165329 countsByYear W28991653292022 @default.
- W2899165329 countsByYear W28991653292023 @default.
- W2899165329 crossrefType "journal-article" @default.
- W2899165329 hasAuthorship W2899165329A5001827320 @default.
- W2899165329 hasAuthorship W2899165329A5021635450 @default.
- W2899165329 hasAuthorship W2899165329A5025975369 @default.
- W2899165329 hasAuthorship W2899165329A5041483680 @default.
- W2899165329 hasAuthorship W2899165329A5062762451 @default.
- W2899165329 hasAuthorship W2899165329A5089130788 @default.
- W2899165329 hasAuthorship W2899165329A5089716389 @default.
- W2899165329 hasAuthorship W2899165329A5090127237 @default.
- W2899165329 hasBestOaLocation W28991653291 @default.
- W2899165329 hasConcept C126322002 @default.
- W2899165329 hasConcept C15744967 @default.
- W2899165329 hasConcept C169760540 @default.
- W2899165329 hasConcept C190041318 @default.
- W2899165329 hasConcept C2776132596 @default.
- W2899165329 hasConcept C2776622722 @default.
- W2899165329 hasConcept C2776837582 @default.
- W2899165329 hasConcept C2778039178 @default.
- W2899165329 hasConcept C2778205975 @default.
- W2899165329 hasConcept C2779134260 @default.
- W2899165329 hasConcept C3008058167 @default.
- W2899165329 hasConcept C522805319 @default.
- W2899165329 hasConcept C524204448 @default.
- W2899165329 hasConcept C548259974 @default.
- W2899165329 hasConcept C551621295 @default.
- W2899165329 hasConcept C71924100 @default.
- W2899165329 hasConceptScore W2899165329C126322002 @default.
- W2899165329 hasConceptScore W2899165329C15744967 @default.
- W2899165329 hasConceptScore W2899165329C169760540 @default.