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• W2899206688 abstract "INTRODUCTION:Soil-transmitted helminths commonly known as intestinal worms are theMost common infections world wide affecting the most deprived countries. AccordingTo WHO estimate nearly a quarter of the world’s population harbour one or moreIntestinal worms.Recent estimates indicate that approximately 1450 million have roundwormInfection, 1300 million have hookworm infection and 1050 million have whip wormInfection1. The economic burden caused by the hookworm, roundworm andWhipworm infection is high and estimated to cost 39.0 million Disability AdjustedLife Years.In 1993, the world bank reported that, within the global burden of disease list, soil-transmitted helminth infections ranked first among children aged 5-14 years ;16.7 million DALYS were lost , which represents 11.3% of the total burden in thisAge group. Using mathematical modelling, it has been estimated that 70% of theTotal burden of diseases due to soil- transmitted helminthic infection can bePrevented in high prevalence communities by treating only school – age children.STH infections rarely cause death but chronic STH infections of school -ageChildren resulting from Ascaris, Trichuris and Hookworm negatively affect allAspects of children’s health, nutrition, cognitive development, learning andEducational access and achievements. Regular de worming can cost effectivelyReverse and prevent much of this morbidity. The availability of Diethyl carbamazine(DEC) and Albendazole (ALB), which have antihelmenthic and antifilarialProperties opens the possibility of controlling geohelminths in a FilariasisElimination programme because of ancillary benefits of albendozole and theResultant enhanced compliance of the population at risk. These properties opens thePossibility of integrating a geohelminth control programme with filariasisElimination programme, where these nematodes occur concurrently.OBJECTIVES :1. To estimate the prevalence of soil-transmitted helminths amongChildren aged 5 – 14 years in rural population.2. To assess the impact of mass drug administration (DEC and ALB) onThe prevalence of above said Soil-transmitted helminths among theSame 5 – 14 years children.3. To find out the possible associated risk factors for the transmission ofSoil- transmitted helminthsA. Socio demographic factors.B. Environmental factorsC. Behavioral factors.JUSTIFICATION :1. Developing countries are reported to be most affected with intestinalhelminthic infection where significant population live in nutritionallycompromised states. It is estimated that number of children (< 15years old) infected with roundworm, hookworm and whip worm in thedeveloping world are 478 millions, 280 millions and 347 millionsrespectively.2. In India, it was estimated the number of cases in school age due tohookworm, round worm and whipworm were 59 millions, 50 millionsand 36 millions and the prevalence were 30%, 25% and 18%respectively.In Tamilnadu, the prevalence of Ascaris, Trichuris and hookwormwere 52.8%, 45.6% and 37.6% respectively in rural school-agechildren but in Urban population the prevalence of Ascaris andTrichuris were 0.5% and 2.01% respectively. Hookworm was notencountered in urban setting.3. Intestinal helminthic infection have been neglected partly becausegreat emphasis has been placed on survival, especially child survivaland less on quality of life, health and productivity of those survive.The subject gains increased importance in school age children as it isa period of significant growth and development5 and in growing stage,children are susceptible to ill effects of parasitic infections as theirneed for nutrients are high6 and have less developed immune systems.Intestinal helminthic infections in this age group have been linkedwith significantly reduced growth and an increased risk for proteinenergy malnutrition including growth stunting, iron deficiencyanaemia and reduced cognitive / psychomotor development.4. The severe financial and logistic difficulties in eradicating povertyand instituting the community-wide programs to improve livingconditions, Sanitation, water supplies and health education that helpto prevent helminthic transmission in the long term poses greatproblem in most developing countries. Population basedchemotherapy with broad spectrum antihelminthic is likely to be theonly way to drastically reduce the prevalence and intensity of the soiltransmittedhelminths.In light of these facts, this study was planned to ascertain theimpact of DEC and ALBENDAZOLE on the prevalence of soiltransmittedhelminthic infections which is given under NVBDCP forFilariasis elimination." @default.
• W2899206688 created "2018-11-09" @default.
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• W2899206688 date "2009-03-01" @default.
• W2899206688 modified "2023-09-27" @default.
• W2899206688 title "A Study of the Impact of Mass Drug Administration (Dec and Albendazole) on the Prevalence of Soil-Transmitted Helminths Among Children Aged 5–14 Years in a Rural Population." @default.
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