Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899224111> ?p ?o ?g. }
- W2899224111 abstract "The hypothalamus controls essential social behaviors and homeostatic functions. However, the cellular architecture of hypothalamic nuclei-including the molecular identity, spatial organization, and function of distinct cell types-is poorly understood. Here, we developed an imaging-based in situ cell-type identification and mapping method and combined it with single-cell RNA-sequencing to create a molecularly annotated and spatially resolved cell atlas of the mouse hypothalamic preoptic region. We profiled ~1 million cells, identified ~70 neuronal populations characterized by distinct neuromodulatory signatures and spatial organizations, and defined specific neuronal populations activated during social behaviors in male and female mice, providing a high-resolution framework for mechanistic investigation of behavior circuits. The approach described opens a new avenue for the construction of cell atlases in diverse tissues and organisms." @default.
- W2899224111 created "2018-11-09" @default.
- W2899224111 creator A5004067604 @default.
- W2899224111 creator A5019100296 @default.
- W2899224111 creator A5024050425 @default.
- W2899224111 creator A5040123918 @default.
- W2899224111 creator A5045006990 @default.
- W2899224111 creator A5051555132 @default.
- W2899224111 creator A5058204526 @default.
- W2899224111 creator A5068175729 @default.
- W2899224111 creator A5087838801 @default.
- W2899224111 creator A5087959577 @default.
- W2899224111 creator A5089691588 @default.
- W2899224111 date "2018-11-16" @default.
- W2899224111 modified "2023-10-16" @default.
- W2899224111 title "Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region" @default.
- W2899224111 cites W1612453552 @default.
- W2899224111 cites W1631320694 @default.
- W2899224111 cites W1886714202 @default.
- W2899224111 cites W1949188903 @default.
- W2899224111 cites W1972618510 @default.
- W2899224111 cites W1974732858 @default.
- W2899224111 cites W1981408763 @default.
- W2899224111 cites W1985656087 @default.
- W2899224111 cites W1987844453 @default.
- W2899224111 cites W1988939568 @default.
- W2899224111 cites W1999633796 @default.
- W2899224111 cites W2001784063 @default.
- W2899224111 cites W2010653277 @default.
- W2899224111 cites W2012847399 @default.
- W2899224111 cites W2016773845 @default.
- W2899224111 cites W2019490156 @default.
- W2899224111 cites W2019946631 @default.
- W2899224111 cites W2026998467 @default.
- W2899224111 cites W2028777780 @default.
- W2899224111 cites W2029881982 @default.
- W2899224111 cites W2030364710 @default.
- W2899224111 cites W2033788106 @default.
- W2899224111 cites W2039254286 @default.
- W2899224111 cites W2042789810 @default.
- W2899224111 cites W2042824787 @default.
- W2899224111 cites W2046270739 @default.
- W2899224111 cites W2052435478 @default.
- W2899224111 cites W2065118621 @default.
- W2899224111 cites W2067203693 @default.
- W2899224111 cites W2079991169 @default.
- W2899224111 cites W2086629747 @default.
- W2899224111 cites W2087453951 @default.
- W2899224111 cites W2088443095 @default.
- W2899224111 cites W2092223956 @default.
- W2899224111 cites W2094109313 @default.
- W2899224111 cites W2102212449 @default.
- W2899224111 cites W2105082339 @default.
- W2899224111 cites W2107177404 @default.
- W2899224111 cites W2107897069 @default.
- W2899224111 cites W2113836851 @default.
- W2899224111 cites W2115754884 @default.
- W2899224111 cites W2115833219 @default.
- W2899224111 cites W2120119174 @default.
- W2899224111 cites W2122321125 @default.
- W2899224111 cites W2123273050 @default.
- W2899224111 cites W2123491442 @default.
- W2899224111 cites W2128381336 @default.
- W2899224111 cites W2130410032 @default.
- W2899224111 cites W2132769858 @default.
- W2899224111 cites W2135937351 @default.
- W2899224111 cites W2144727302 @default.
- W2899224111 cites W2151013106 @default.
- W2899224111 cites W2158404383 @default.
- W2899224111 cites W2160133414 @default.
- W2899224111 cites W2190545194 @default.
- W2899224111 cites W2231058499 @default.
- W2899224111 cites W2286142055 @default.
- W2899224111 cites W2496172413 @default.
- W2899224111 cites W2510746232 @default.
- W2899224111 cites W2516756255 @default.
- W2899224111 cites W2519797740 @default.
- W2899224111 cites W2520858613 @default.
- W2899224111 cites W2520969273 @default.
- W2899224111 cites W2533012945 @default.
- W2899224111 cites W2550247089 @default.
- W2899224111 cites W2562003322 @default.
- W2899224111 cites W2571308267 @default.
- W2899224111 cites W2572662684 @default.
- W2899224111 cites W2583012620 @default.
- W2899224111 cites W2586421092 @default.
- W2899224111 cites W2601723752 @default.
- W2899224111 cites W2602954002 @default.
- W2899224111 cites W2616271045 @default.
- W2899224111 cites W2620827867 @default.
- W2899224111 cites W2744176737 @default.
- W2899224111 cites W2744478946 @default.
- W2899224111 cites W2751012569 @default.
- W2899224111 cites W2754841759 @default.
- W2899224111 cites W2759615793 @default.
- W2899224111 cites W2763776271 @default.
- W2899224111 cites W2776864790 @default.
- W2899224111 cites W2783929557 @default.
- W2899224111 cites W2785264903 @default.
- W2899224111 cites W2790719087 @default.