FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899227718> ?p ?o ?g. }

• W2899227718 endingPage "85" @default.
• W2899227718 startingPage "80" @default.
• W2899227718 abstract "Although its first military use in Ypres was 100 years ago, no causal therapy for sulfur mustard (SM) intoxications exists so far. To improve the therapeutic options for the treatment of SM intoxications, we developed a co-culture of keratinocytes (HaCaT cells) and immunocompetent cells (THP-1 cells) to identify potential substances for further research. Here, we report on the influence of necrosulfonamide (NSA) on the course of a SM intoxication in vitro. The cells were challenged with 100, 200 and 300 μM SM and after 1 h treated with NSA (1, 5, 10 μM). NSA was chosen for its known ability to inhibit necroptosis, a specialized pathway of programmed necrosis. However, in our settings NSA showed only mild effects on necrotic cell death after SM intoxication, whereas it had an immense ability to prevent apoptosis. Furthermore, NSA was able to reduce the production of interleukin-6 and interleukin-8 at certain concentrations. Our data highlight NSA as a candidate compound to address cell death and inflammation in SM exposure." @default.
• W2899227718 created "2018-11-09" @default.
• W2899227718 creator A5007053715 @default.
• W2899227718 creator A5037239037 @default.
• W2899227718 creator A5042550353 @default.
• W2899227718 creator A5052276644 @default.
• W2899227718 creator A5065854689 @default.
• W2899227718 creator A5078195672 @default.
• W2899227718 creator A5083874260 @default.
• W2899227718 creator A5087697455 @default.
• W2899227718 creator A5090764321 @default.
• W2899227718 date "2019-01-01" @default.
• W2899227718 modified "2023-10-09" @default.
• W2899227718 title "Necrosulfonamide – Unexpected effect in the course of a sulfur mustard intoxication" @default.
• W2899227718 cites W1557138983 @default.
• W2899227718 cites W1678823535 @default.
• W2899227718 cites W1953067327 @default.
• W2899227718 cites W1967237073 @default.
• W2899227718 cites W1974941717 @default.
• W2899227718 cites W1980484161 @default.
• W2899227718 cites W1984751626 @default.
• W2899227718 cites W1987953642 @default.
• W2899227718 cites W1994028950 @default.
• W2899227718 cites W1994180565 @default.
• W2899227718 cites W2004266769 @default.
• W2899227718 cites W2005115820 @default.
• W2899227718 cites W2005602906 @default.
• W2899227718 cites W2006747293 @default.
• W2899227718 cites W2015206944 @default.
• W2899227718 cites W2019470303 @default.
• W2899227718 cites W2019764212 @default.
• W2899227718 cites W2025196191 @default.
• W2899227718 cites W2030194678 @default.
• W2899227718 cites W2040566850 @default.
• W2899227718 cites W2052605153 @default.
• W2899227718 cites W2052853635 @default.
• W2899227718 cites W2056774514 @default.
• W2899227718 cites W2062798251 @default.
• W2899227718 cites W2063251795 @default.
• W2899227718 cites W2090631453 @default.
• W2899227718 cites W2110796758 @default.
• W2899227718 cites W2115696589 @default.
• W2899227718 cites W2127310510 @default.
• W2899227718 cites W2132161879 @default.
• W2899227718 cites W2143464311 @default.
• W2899227718 cites W2157344044 @default.
• W2899227718 cites W2160423806 @default.
• W2899227718 cites W2164334984 @default.
• W2899227718 cites W2291832556 @default.
• W2899227718 cites W2394570772 @default.
• W2899227718 cites W2799624283 @default.
• W2899227718 cites W2888057265 @default.
• W2899227718 doi "https://doi.org/10.1016/j.cbi.2018.10.030" @default.
• W2899227718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30391637" @default.
• W2899227718 hasPublicationYear "2019" @default.
• W2899227718 type Work @default.
• W2899227718 sameAs 2899227718 @default.
• W2899227718 citedByCount "4" @default.
• W2899227718 countsByYear W28992277182020 @default.
• W2899227718 countsByYear W28992277182022 @default.
• W2899227718 crossrefType "journal-article" @default.
• W2899227718 hasAuthorship W2899227718A5007053715 @default.
• W2899227718 hasAuthorship W2899227718A5037239037 @default.
• W2899227718 hasAuthorship W2899227718A5042550353 @default.
• W2899227718 hasAuthorship W2899227718A5052276644 @default.
• W2899227718 hasAuthorship W2899227718A5065854689 @default.
• W2899227718 hasAuthorship W2899227718A5078195672 @default.
• W2899227718 hasAuthorship W2899227718A5083874260 @default.
• W2899227718 hasAuthorship W2899227718A5087697455 @default.
• W2899227718 hasAuthorship W2899227718A5090764321 @default.
• W2899227718 hasConcept C118995209 @default.
• W2899227718 hasConcept C126322002 @default.
• W2899227718 hasConcept C185592680 @default.
• W2899227718 hasConcept C190283241 @default.
• W2899227718 hasConcept C202751555 @default.
• W2899227718 hasConcept C203014093 @default.
• W2899227718 hasConcept C2776914184 @default.
• W2899227718 hasConcept C2780644109 @default.
• W2899227718 hasConcept C29730261 @default.
• W2899227718 hasConcept C31573885 @default.
• W2899227718 hasConcept C55493867 @default.
• W2899227718 hasConcept C71924100 @default.
• W2899227718 hasConcept C94030615 @default.
• W2899227718 hasConcept C98274493 @default.
• W2899227718 hasConceptScore W2899227718C118995209 @default.
• W2899227718 hasConceptScore W2899227718C126322002 @default.
• W2899227718 hasConceptScore W2899227718C185592680 @default.
• W2899227718 hasConceptScore W2899227718C190283241 @default.
• W2899227718 hasConceptScore W2899227718C202751555 @default.
• W2899227718 hasConceptScore W2899227718C203014093 @default.
• W2899227718 hasConceptScore W2899227718C2776914184 @default.
• W2899227718 hasConceptScore W2899227718C2780644109 @default.
• W2899227718 hasConceptScore W2899227718C29730261 @default.
• W2899227718 hasConceptScore W2899227718C31573885 @default.
• W2899227718 hasConceptScore W2899227718C55493867 @default.
• W2899227718 hasConceptScore W2899227718C71924100 @default.
• W2899227718 hasConceptScore W2899227718C94030615 @default.
• W2899227718 hasConceptScore W2899227718C98274493 @default.

• next