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- W2899242135 abstract "Abstract This study quantified the fatty acid profile with emphasis on the stereo-specifically numbered ( sn ) 2 positional distribution in TAG and the composition of main phospholipids at different lactation stages. Colostrum milk ( n 70), transitional milk ( n 96) and mature milk ( n 82) were obtained longitudinally from healthy lactating women in Shanghai. During lactation, total fatty acid content increased, with SFA dominating in fatty acid profile. A high ratio of n -6: n -3 PUFA was observed as 11:1 over lactation due to the abundance of linoleic acid in Chinese human milk. As the main SFA, palmitic acid showed absolute sn -2 selectivity, while oleic acid, linoleic acid and α -linolenic acid, the main unsaturated fatty acids, were primarily esterified at the sn -1 and sn -3 positions. Nervonic acid and C22 PUFA including DHA were more enriched in colostrum with an sn -2 positional preference. A total of three dominant phospholipids (phosphatidylethanolamine (PE), phosphatidylcholine (PC) and sphingomyelin (SM)) were analysed in the collected samples, and each showed a decline in amount over lactation. PC was the dominant compound followed by SM and PE. With prolonged breast-feeding time, percentage of PE in total phospholipids remained constant, but PC decreased, and SM increased. Results from this study indicated a lipid profile different from Western reports and may aid the development of future infant formula more suitable for Chinese babies." @default.
- W2899242135 created "2018-11-09" @default.
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- W2899242135 date "2018-10-31" @default.
- W2899242135 modified "2023-10-11" @default.
- W2899242135 title "Fatty acid positional distribution (<i>sn</i>-2 fatty acids) and phospholipid composition in Chinese breast milk from colostrum to mature stage" @default.
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- W2899242135 doi "https://doi.org/10.1017/s0007114518002994" @default.
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