FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899278308> ?p ?o ?g. }

• W2899278308 endingPage "e5799" @default.
• W2899278308 startingPage "e5799" @default.
• W2899278308 abstract "Mitochondrial pyruvate carrier 1 (MPC1) is a component of the MPC1/MPC2 heterodimer that facilitates the transport of pyruvate into mitochondria. Pyruvate plays a central role in carbohydrate, fatty, and amino acid catabolism. The present study examined epididymal white adipose tissue (eWAT) and intrascapular brown adipose tissue (iBAT) from MPC1± mice following 24 weeks of feeding, which indicated low energy accumulation as evidenced by low body and eWAT weight and adipocyte volume. To characterize molecular changes in energy metabolism, we analyzed the transcriptomes of the adipose tissues using RNA-Sequencing (RNA-Seq). The results showed that the fatty acid oxidation pathway was activated and several genes involved in this pathway were upregulated. Furthermore, qPCR and western blotting indicated that numerous genes and proteins that participate in lipolysis were also upregulated. Based on these findings, we propose that the energy deficiency caused by reduced MPC1 activity can be alleviated by activating the lipolytic pathway." @default.
• W2899278308 created "2018-11-09" @default.
• W2899278308 creator A5018983616 @default.
• W2899278308 creator A5023601668 @default.
• W2899278308 creator A5028481522 @default.
• W2899278308 creator A5049698883 @default.
• W2899278308 creator A5076273065 @default.
• W2899278308 creator A5080175890 @default.
• W2899278308 date "2018-10-30" @default.
• W2899278308 modified "2023-10-13" @default.
• W2899278308 title "Adipose tissues of MPC1^± mice display altered lipid metabolism-related enzyme expression levels" @default.
• W2899278308 cites W1762789982 @default.
• W2899278308 cites W1928389510 @default.
• W2899278308 cites W1932854961 @default.
• W2899278308 cites W1964284218 @default.
• W2899278308 cites W1981509058 @default.
• W2899278308 cites W1983107759 @default.
• W2899278308 cites W1990008701 @default.
• W2899278308 cites W1994472120 @default.
• W2899278308 cites W2007012192 @default.
• W2899278308 cites W2010987575 @default.
• W2899278308 cites W2013771848 @default.
• W2899278308 cites W2021787243 @default.
• W2899278308 cites W2029142939 @default.
• W2899278308 cites W2034810986 @default.
• W2899278308 cites W2040857331 @default.
• W2899278308 cites W2058387746 @default.
• W2899278308 cites W2071450001 @default.
• W2899278308 cites W2071628225 @default.
• W2899278308 cites W2085951097 @default.
• W2899278308 cites W2102186262 @default.
• W2899278308 cites W2104547476 @default.
• W2899278308 cites W2118276992 @default.
• W2899278308 cites W2125149721 @default.
• W2899278308 cites W2125660831 @default.
• W2899278308 cites W2326389904 @default.
• W2899278308 cites W2336833178 @default.
• W2899278308 cites W2381125605 @default.
• W2899278308 cites W2411061833 @default.
• W2899278308 cites W2411299779 @default.
• W2899278308 cites W2487481546 @default.
• W2899278308 cites W2553707323 @default.
• W2899278308 cites W2596237154 @default.
• W2899278308 cites W2760183031 @default.
• W2899278308 cites W2770696006 @default.
• W2899278308 cites W2788103046 @default.
• W2899278308 cites W2793972197 @default.
• W2899278308 cites W71619780 @default.
• W2899278308 doi "https://doi.org/10.7717/peerj.5799" @default.
• W2899278308 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6214228" @default.
• W2899278308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30397542" @default.
• W2899278308 hasPublicationYear "2018" @default.
• W2899278308 type Work @default.
• W2899278308 sameAs 2899278308 @default.
• W2899278308 citedByCount "8" @default.
• W2899278308 countsByYear W28992783082019 @default.
• W2899278308 countsByYear W28992783082020 @default.
• W2899278308 countsByYear W28992783082022 @default.
• W2899278308 countsByYear W28992783082023 @default.
• W2899278308 crossrefType "journal-article" @default.
• W2899278308 hasAuthorship W2899278308A5018983616 @default.
• W2899278308 hasAuthorship W2899278308A5023601668 @default.
• W2899278308 hasAuthorship W2899278308A5028481522 @default.
• W2899278308 hasAuthorship W2899278308A5049698883 @default.
• W2899278308 hasAuthorship W2899278308A5076273065 @default.
• W2899278308 hasAuthorship W2899278308A5080175890 @default.
• W2899278308 hasBestOaLocation W28992783081 @default.
• W2899278308 hasConcept C104317684 @default.
• W2899278308 hasConcept C127561419 @default.
• W2899278308 hasConcept C134018914 @default.
• W2899278308 hasConcept C140985366 @default.
• W2899278308 hasConcept C151955695 @default.
• W2899278308 hasConcept C171089720 @default.
• W2899278308 hasConcept C185592680 @default.
• W2899278308 hasConcept C2776175234 @default.
• W2899278308 hasConcept C2780642333 @default.
• W2899278308 hasConcept C4733338 @default.
• W2899278308 hasConcept C55493867 @default.
• W2899278308 hasConcept C62231903 @default.
• W2899278308 hasConcept C82714985 @default.
• W2899278308 hasConcept C86803240 @default.
• W2899278308 hasConcept C96942376 @default.
• W2899278308 hasConceptScore W2899278308C104317684 @default.
• W2899278308 hasConceptScore W2899278308C127561419 @default.
• W2899278308 hasConceptScore W2899278308C134018914 @default.
• W2899278308 hasConceptScore W2899278308C140985366 @default.
• W2899278308 hasConceptScore W2899278308C151955695 @default.
• W2899278308 hasConceptScore W2899278308C171089720 @default.
• W2899278308 hasConceptScore W2899278308C185592680 @default.
• W2899278308 hasConceptScore W2899278308C2776175234 @default.
• W2899278308 hasConceptScore W2899278308C2780642333 @default.
• W2899278308 hasConceptScore W2899278308C4733338 @default.
• W2899278308 hasConceptScore W2899278308C55493867 @default.
• W2899278308 hasConceptScore W2899278308C62231903 @default.
• W2899278308 hasConceptScore W2899278308C82714985 @default.
• W2899278308 hasConceptScore W2899278308C86803240 @default.
• W2899278308 hasConceptScore W2899278308C96942376 @default.
• W2899278308 hasLocation W28992783081 @default.

• next