FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899331106> ?p ?o ?g. }

• W2899331106 endingPage "e223" @default.
• W2899331106 startingPage "e222" @default.
• W2899331106 abstract "Objectives: To investigate cerebral circulation in controlled arterial hypertension patients 2 stage of working age with mild and moderate cognitive disorders (CD), to determine the effectiveness of fixed combination of nootropic agent (phenibutum) and anticholinergic drug (ipidacrinum). Methods: Observed 67 patients with controlled hypertension 2 stage and CD. The median age − 57,3 ± 8,91 years. The average duration of hypertension was 11,5 ± 6,2 years. Cognitive functioning was assessed by MoCA scale. Blood flow in the middle cerebral artery (MCA) was studied by transcranial Doppler (TCD) on the HDI 7, Philips, USA with functional respiratory hypo- and hypercapnic ventilation tests to assess the integrative index of vasomotor reactivity: IVMR = [(Vapnea–Vhyper)/V0]•100%,Vapnea – the average maximum velocity of blood flow after 20 s of apnea (cm/s), Vhyper – the average maximum velocity of blood flow after 20 s of hyperventilation (cm/s), V0 — the average maximum velocity at rest (cm/s)). All patients received a personalized antihypertensive therapy and were randomized in two groups; 30 of the main group of treatment were added fixed combination of phenibutum 300 mg and ipidacrinum 5 mg x 3 times a day. Timing of treatment and surveillance was 45 days. Results: Only the patients of the main group decreased CD by 2.39 ± 0.75 points according to data MoCA scale on the base of improvements of cerebral blood flow. As to the data of TCD MCA monitoring of respiratory tests during involvement time a significant improvement of IVMR by 22%, (p > 0,05) in that group were achieved. Conclusion: Functional respiratory tests can be used for control the early brain damage. Additional prescription of fixed combination of nootropic agent and anticholinergic drug is adequate for correction cognitive disorders in hypertension patients." @default.
• W2899331106 created "2018-11-09" @default.
• W2899331106 creator A5008105710 @default.
• W2899331106 creator A5082405325 @default.
• W2899331106 creator A5087099301 @default.
• W2899331106 date "2018-10-01" @default.
• W2899331106 modified "2023-10-16" @default.
• W2899331106 title "A13661 Cerebral circulation and cognitive functions in arterial hypertension, optimization of diagnosis and treatment" @default.
• W2899331106 doi "https://doi.org/10.1097/01.hjh.0000548909.26355.19" @default.
• W2899331106 hasPublicationYear "2018" @default.
• W2899331106 type Work @default.
• W2899331106 sameAs 2899331106 @default.
• W2899331106 citedByCount "1" @default.
• W2899331106 countsByYear W28993311062019 @default.
• W2899331106 crossrefType "journal-article" @default.
• W2899331106 hasAuthorship W2899331106A5008105710 @default.
• W2899331106 hasAuthorship W2899331106A5082405325 @default.
• W2899331106 hasAuthorship W2899331106A5087099301 @default.
• W2899331106 hasConcept C119671327 @default.
• W2899331106 hasConcept C126322002 @default.
• W2899331106 hasConcept C157767197 @default.
• W2899331106 hasConcept C164705383 @default.
• W2899331106 hasConcept C191616109 @default.
• W2899331106 hasConcept C2775841333 @default.
• W2899331106 hasConcept C2777405951 @default.
• W2899331106 hasConcept C2777449187 @default.
• W2899331106 hasConcept C42219234 @default.
• W2899331106 hasConcept C541997718 @default.
• W2899331106 hasConcept C71924100 @default.
• W2899331106 hasConceptScore W2899331106C119671327 @default.
• W2899331106 hasConceptScore W2899331106C126322002 @default.
• W2899331106 hasConceptScore W2899331106C157767197 @default.
• W2899331106 hasConceptScore W2899331106C164705383 @default.
• W2899331106 hasConceptScore W2899331106C191616109 @default.
• W2899331106 hasConceptScore W2899331106C2775841333 @default.
• W2899331106 hasConceptScore W2899331106C2777405951 @default.
• W2899331106 hasConceptScore W2899331106C2777449187 @default.
• W2899331106 hasConceptScore W2899331106C42219234 @default.
• W2899331106 hasConceptScore W2899331106C541997718 @default.
• W2899331106 hasConceptScore W2899331106C71924100 @default.
• W2899331106 hasLocation W28993311061 @default.
• W2899331106 hasOpenAccess W2899331106 @default.
• W2899331106 hasPrimaryLocation W28993311061 @default.
• W2899331106 hasRelatedWork W1967537123 @default.
• W2899331106 hasRelatedWork W1992482607 @default.
• W2899331106 hasRelatedWork W2005753181 @default.
• W2899331106 hasRelatedWork W2025183758 @default.
• W2899331106 hasRelatedWork W2040046911 @default.
• W2899331106 hasRelatedWork W2064911755 @default.
• W2899331106 hasRelatedWork W2077030365 @default.
• W2899331106 hasRelatedWork W2408393479 @default.
• W2899331106 hasRelatedWork W2886631822 @default.
• W2899331106 hasRelatedWork W3145399092 @default.
• W2899331106 hasVolume "36" @default.
• W2899331106 isParatext "false" @default.
• W2899331106 isRetracted "false" @default.
• W2899331106 magId "2899331106" @default.
• W2899331106 workType "article" @default.