Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899358639> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2899358639 endingPage "416" @default.
- W2899358639 startingPage "412" @default.
- W2899358639 abstract "Peritoneal metastasis (PM) in a gastrointestinal cancer is associated with a poor prognosis. Various guidelines recommend palliative chemotherapy in these patients as cure is not achievable. However, hyperthermic intraperitoneal chemotherapy (HIPEC) in combination with cytoreductive surgery (CRS) can achieve long-term survival with low morbidity in selected patients. During the last decades, CRS and HIPEC have been performed in a number of indications, aiming for long-term survival. What is more, new drugs and treatment regimens demonstrate favorable results.The recently published important literature on PM in gastrointestinal cancer was analyzed.Resection of isolated PM in a gastrointestinal cancer should be considered, and HIPEC is feasible. However, there is a lack of well-designed randomized controlled trials (RCTs) in gastrointestinal cancer-related PM. Many RCTs are being conducted across the world whose results will be available in 1-2 years. Systemic chemotherapy alone as an adequate management plan for isolated PM in a gastrointestinal cancer is not compatible with a high standard of care. Formulating an optimal plan combining the benefits of CRS and HIPEC coupled with systemic chemotherapy is a necessary task of the multidisciplinary team. Proper selection of the patients for CRS and HIPEC is necessary to achieve maximal oncological benefit and minimal perioperative morbidity and mortality.A multidisciplinary approach combining the benefits of both CRS and HIPEC, and systemic chemotherapy is the way forward to manage those patients with gastrointestinal cancer and PM. Further studies are warranted to identify the selection variables for CRS and HIPEC." @default.
- W2899358639 created "2018-11-09" @default.
- W2899358639 creator A5010130023 @default.
- W2899358639 creator A5052521183 @default.
- W2899358639 creator A5082392739 @default.
- W2899358639 date "2018-01-01" @default.
- W2899358639 modified "2023-10-03" @default.
- W2899358639 title "Hyperthermic Intraperitoneal Chemotherapy - Fading Perspective in the Light of Modern Systemic Chemotherapy?" @default.
- W2899358639 cites W17791541 @default.
- W2899358639 cites W1927044883 @default.
- W2899358639 cites W1975931206 @default.
- W2899358639 cites W1984579087 @default.
- W2899358639 cites W1992408996 @default.
- W2899358639 cites W2004554342 @default.
- W2899358639 cites W2039775903 @default.
- W2899358639 cites W2042210669 @default.
- W2899358639 cites W2053510750 @default.
- W2899358639 cites W2085618369 @default.
- W2899358639 cites W2093268532 @default.
- W2899358639 cites W2093696966 @default.
- W2899358639 cites W2100439220 @default.
- W2899358639 cites W2102076812 @default.
- W2899358639 cites W2104186733 @default.
- W2899358639 cites W2109794223 @default.
- W2899358639 cites W2116274195 @default.
- W2899358639 cites W2130522735 @default.
- W2899358639 cites W2143086668 @default.
- W2899358639 cites W2312545823 @default.
- W2899358639 cites W2411757157 @default.
- W2899358639 cites W2917837889 @default.
- W2899358639 cites W9145604 @default.
- W2899358639 doi "https://doi.org/10.1159/000493493" @default.
- W2899358639 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6341355" @default.
- W2899358639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30675484" @default.
- W2899358639 hasPublicationYear "2018" @default.
- W2899358639 type Work @default.
- W2899358639 sameAs 2899358639 @default.
- W2899358639 citedByCount "7" @default.
- W2899358639 countsByYear W28993586392018 @default.
- W2899358639 countsByYear W28993586392019 @default.
- W2899358639 countsByYear W28993586392021 @default.
- W2899358639 countsByYear W28993586392022 @default.
- W2899358639 crossrefType "journal-article" @default.
- W2899358639 hasAuthorship W2899358639A5010130023 @default.
- W2899358639 hasAuthorship W2899358639A5052521183 @default.
- W2899358639 hasAuthorship W2899358639A5082392739 @default.
- W2899358639 hasBestOaLocation W28993586391 @default.
- W2899358639 hasConcept C121608353 @default.
- W2899358639 hasConcept C126322002 @default.
- W2899358639 hasConcept C141071460 @default.
- W2899358639 hasConcept C143998085 @default.
- W2899358639 hasConcept C168563851 @default.
- W2899358639 hasConcept C177713679 @default.
- W2899358639 hasConcept C2776694085 @default.
- W2899358639 hasConcept C2779458272 @default.
- W2899358639 hasConcept C2780427987 @default.
- W2899358639 hasConcept C2994223192 @default.
- W2899358639 hasConcept C526805850 @default.
- W2899358639 hasConcept C542804219 @default.
- W2899358639 hasConcept C71924100 @default.
- W2899358639 hasConceptScore W2899358639C121608353 @default.
- W2899358639 hasConceptScore W2899358639C126322002 @default.
- W2899358639 hasConceptScore W2899358639C141071460 @default.
- W2899358639 hasConceptScore W2899358639C143998085 @default.
- W2899358639 hasConceptScore W2899358639C168563851 @default.
- W2899358639 hasConceptScore W2899358639C177713679 @default.
- W2899358639 hasConceptScore W2899358639C2776694085 @default.
- W2899358639 hasConceptScore W2899358639C2779458272 @default.
- W2899358639 hasConceptScore W2899358639C2780427987 @default.
- W2899358639 hasConceptScore W2899358639C2994223192 @default.
- W2899358639 hasConceptScore W2899358639C526805850 @default.
- W2899358639 hasConceptScore W2899358639C542804219 @default.
- W2899358639 hasConceptScore W2899358639C71924100 @default.
- W2899358639 hasIssue "6" @default.
- W2899358639 hasLocation W28993586391 @default.
- W2899358639 hasLocation W28993586392 @default.
- W2899358639 hasLocation W28993586393 @default.
- W2899358639 hasLocation W28993586394 @default.
- W2899358639 hasOpenAccess W2899358639 @default.
- W2899358639 hasPrimaryLocation W28993586391 @default.
- W2899358639 hasRelatedWork W1619421778 @default.
- W2899358639 hasRelatedWork W2067366728 @default.
- W2899358639 hasRelatedWork W2081048013 @default.
- W2899358639 hasRelatedWork W2368826177 @default.
- W2899358639 hasRelatedWork W2517704322 @default.
- W2899358639 hasRelatedWork W2581545833 @default.
- W2899358639 hasRelatedWork W2749916783 @default.
- W2899358639 hasRelatedWork W2950495184 @default.
- W2899358639 hasRelatedWork W3210501761 @default.
- W2899358639 hasRelatedWork W4308233102 @default.
- W2899358639 hasVolume "34" @default.
- W2899358639 isParatext "false" @default.
- W2899358639 isRetracted "false" @default.
- W2899358639 magId "2899358639" @default.
- W2899358639 workType "article" @default.