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- W2899361741 abstract "Diseases of large vessels include inflammatory, infectious, degenerative, and neoplastic conditions. Inflammatory large vessel diseases include atherosclerosis, aortitis, periaortitis and inflammatory atherosclerotic aneurysms. A pathological classification scheme is described for aortitis and periaortitis based on the pattern of the inflammatory infiltrate: granulomatous/giant cell pattern, lymphoplasmacytic pattern, mixed inflammatory pattern, and the suppurative pattern. Degenerative aortic diseases include aging and genetic syndromes such as Marfan syndrome and Loeys-Dietz syndrome. These conditions cause degenerative changes of the media such as mucoid extracellular matrix accumulation (MEMA), elastic fibre fragmentation and/or loss and smooth muscle cell nuclei loss. There are multiple primary sarcomas of large vessels including angiosarcomas, leiomyosarcomas and undifferentiated sarcomas." @default.
- W2899361741 created "2018-11-09" @default.
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- W2899361741 date "2018-11-01" @default.
- W2899361741 modified "2023-09-25" @default.
- W2899361741 title "Pathology of large vessel disease" @default.
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- W2899361741 doi "https://doi.org/10.1016/j.mpdhp.2018.10.005" @default.
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