FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899369531> ?p ?o ?g. }

• W2899369531 abstract "Abstract Structural genomic abnormalities, including balanced chromosomal rearrangements, copy number gains and losses and copy-neutral loss-of-heterozygosity (CN-LOH) represent an important category of diagnostic, prognostic and therapeutic markers in acute myeloid leukemia (AML). Genome-wide evaluation for copy number abnormalities (CNAs) is at present performed by karyotype analysis which has low resolution and is unobtainable in a subset of cases. Furthermore, examination for possible CN-LOH in leukemia cells is at present not routinely performed in the clinical setting. Chromosomal microarray (CMA) analysis is a widely available assay for CNAs and CN-LOH in diagnostic laboratories, but there are currently no guidelines how to best incorporate this technology into clinical testing algorithms for neoplastic diseases including AML. The Cancer Genomics Consortium Working Group for Myeloid Neoplasms performed an extensive review of peer-reviewed publications focused on CMA analysis in AML. Here we summarize evidence regarding clinical utility of CMA analysis in AML extracted from published data, and provide recommendations for optimal utilization of CMA testing in the diagnostic workup. In addition, we provide a list of CNAs and CN-LOH regions which have documented clinical significance in diagnosis, prognosis and treatment decisions in AML." @default.
• W2899369531 created "2018-11-09" @default.
• W2899369531 creator A5002611478 @default.
• W2899369531 creator A5005959019 @default.
• W2899369531 creator A5026614628 @default.
• W2899369531 creator A5037393607 @default.
• W2899369531 creator A5037972294 @default.
• W2899369531 creator A5038296860 @default.
• W2899369531 creator A5042991227 @default.
• W2899369531 creator A5045975673 @default.
• W2899369531 creator A5047620115 @default.
• W2899369531 creator A5058597905 @default.
• W2899369531 creator A5059373442 @default.
• W2899369531 creator A5068661649 @default.
• W2899369531 creator A5069100135 @default.
• W2899369531 creator A5073052072 @default.
• W2899369531 creator A5073322251 @default.
• W2899369531 creator A5080327876 @default.
• W2899369531 creator A5084132159 @default.
• W2899369531 creator A5089936608 @default.
• W2899369531 date "2018-01-01" @default.
• W2899369531 modified "2023-10-01" @default.
• W2899369531 title "Assessing copy number abnormalities and copy-neutral loss-of-heterozygosity across the genome as best practice in diagnostic evaluation of acute myeloid leukemia: An evidence-based review from the cancer genomics consortium (CGC) myeloid neoplasms working group" @default.
• W2899369531 hasPublicationYear "2018" @default.
• W2899369531 type Work @default.
• W2899369531 sameAs 2899369531 @default.
• W2899369531 citedByCount "0" @default.
• W2899369531 crossrefType "book-chapter" @default.
• W2899369531 hasAuthorship W2899369531A5002611478 @default.
• W2899369531 hasAuthorship W2899369531A5005959019 @default.
• W2899369531 hasAuthorship W2899369531A5026614628 @default.
• W2899369531 hasAuthorship W2899369531A5037393607 @default.
• W2899369531 hasAuthorship W2899369531A5037972294 @default.
• W2899369531 hasAuthorship W2899369531A5038296860 @default.
• W2899369531 hasAuthorship W2899369531A5042991227 @default.
• W2899369531 hasAuthorship W2899369531A5045975673 @default.
• W2899369531 hasAuthorship W2899369531A5047620115 @default.
• W2899369531 hasAuthorship W2899369531A5058597905 @default.
• W2899369531 hasAuthorship W2899369531A5059373442 @default.
• W2899369531 hasAuthorship W2899369531A5068661649 @default.
• W2899369531 hasAuthorship W2899369531A5069100135 @default.
• W2899369531 hasAuthorship W2899369531A5073052072 @default.
• W2899369531 hasAuthorship W2899369531A5073322251 @default.
• W2899369531 hasAuthorship W2899369531A5080327876 @default.
• W2899369531 hasAuthorship W2899369531A5084132159 @default.
• W2899369531 hasAuthorship W2899369531A5089936608 @default.
• W2899369531 hasConcept C104317684 @default.
• W2899369531 hasConcept C120821319 @default.
• W2899369531 hasConcept C121608353 @default.
• W2899369531 hasConcept C141231307 @default.
• W2899369531 hasConcept C143589142 @default.
• W2899369531 hasConcept C143998085 @default.
• W2899369531 hasConcept C166608930 @default.
• W2899369531 hasConcept C180754005 @default.
• W2899369531 hasConcept C189206191 @default.
• W2899369531 hasConcept C2778729363 @default.
• W2899369531 hasConcept C502942594 @default.
• W2899369531 hasConcept C54355233 @default.
• W2899369531 hasConcept C60644358 @default.
• W2899369531 hasConcept C70721500 @default.
• W2899369531 hasConcept C71924100 @default.
• W2899369531 hasConcept C86803240 @default.
• W2899369531 hasConceptScore W2899369531C104317684 @default.
• W2899369531 hasConceptScore W2899369531C120821319 @default.
• W2899369531 hasConceptScore W2899369531C121608353 @default.
• W2899369531 hasConceptScore W2899369531C141231307 @default.
• W2899369531 hasConceptScore W2899369531C143589142 @default.
• W2899369531 hasConceptScore W2899369531C143998085 @default.
• W2899369531 hasConceptScore W2899369531C166608930 @default.
• W2899369531 hasConceptScore W2899369531C180754005 @default.
• W2899369531 hasConceptScore W2899369531C189206191 @default.
• W2899369531 hasConceptScore W2899369531C2778729363 @default.
• W2899369531 hasConceptScore W2899369531C502942594 @default.
• W2899369531 hasConceptScore W2899369531C54355233 @default.
• W2899369531 hasConceptScore W2899369531C60644358 @default.
• W2899369531 hasConceptScore W2899369531C70721500 @default.
• W2899369531 hasConceptScore W2899369531C71924100 @default.
• W2899369531 hasConceptScore W2899369531C86803240 @default.
• W2899369531 hasOpenAccess W2899369531 @default.
• W2899369531 hasRelatedWork W1964855123 @default.
• W2899369531 hasRelatedWork W1966629629 @default.
• W2899369531 hasRelatedWork W1972097827 @default.
• W2899369531 hasRelatedWork W2047463825 @default.
• W2899369531 hasRelatedWork W2120174899 @default.
• W2899369531 hasRelatedWork W2169173170 @default.
• W2899369531 hasRelatedWork W2173014627 @default.
• W2899369531 hasRelatedWork W2485801504 @default.
• W2899369531 hasRelatedWork W2622297982 @default.
• W2899369531 hasRelatedWork W2763034227 @default.
• W2899369531 hasRelatedWork W2803164167 @default.
• W2899369531 hasRelatedWork W2883750001 @default.
• W2899369531 hasRelatedWork W2894767012 @default.
• W2899369531 hasRelatedWork W2896048754 @default.
• W2899369531 hasRelatedWork W2956014841 @default.
• W2899369531 hasRelatedWork W2967535307 @default.
• W2899369531 hasRelatedWork W3022286282 @default.
• W2899369531 hasRelatedWork W3043780598 @default.
• W2899369531 hasRelatedWork W3133531614 @default.
• W2899369531 hasRelatedWork W3164233308 @default.
• W2899369531 isParatext "false" @default.

• next