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- W2899476493 endingPage "365" @default.
- W2899476493 startingPage "346" @default.
- W2899476493 abstract "Cyanobacteria are photosynthetic microorganisms distributed globally in aquatic and terrestrial environments. They are also industrially cultivated to be used as dietary supplements, as they have a high nutritional value; however, they are also known to produce a wide range of toxic secondary metabolites, called cyanotoxins. BMAA (β-methylamino-l-alanine) and its most common structural isomers, DAB (2,4-diaminobutyric acid) and AEG (N-2-aminoethylglycine) produced by cyanobacteria, are non-proteinogenic amino acids that have been associated with neurodegenerative diseases. A possible route of exposure to those amino acids is through consumption of food supplements based on cyanobacteria. The review critically discusses existing reports regarding the occurrence of BMAA, DAB and AEG in cyanobacteria and cyanobacteria-based food supplements. It is shown that inconsistencies in reported results could be attributed to performance of different methods of extraction and analysis applied and in ambiguities regarding determination of soluble and bound fractions of the compounds. The critical aspect of this review aims to grow awareness of human intake of neurotoxic amino acids, while results presented in literature concerning dietary supplements aim to promote further research, quality control as well as development of guidelines for cyanotoxins in food products." @default.
- W2899476493 created "2018-11-09" @default.
- W2899476493 creator A5012221830 @default.
- W2899476493 creator A5014719884 @default.
- W2899476493 creator A5018194920 @default.
- W2899476493 creator A5033879746 @default.
- W2899476493 date "2019-03-01" @default.
- W2899476493 modified "2023-10-01" @default.
- W2899476493 title "Neurotoxin BMAA and its isomeric amino acids in cyanobacteria and cyanobacteria-based food supplements" @default.
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