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• W2899495866 startingPage "126" @default.
• W2899495866 abstract "We have investigated myoglobin protein denaturation using the zwitterionic detergent Empigen BB (EBB, N,N-Dimethyl-N-dodecylglycine betaine). A combination of absorbance, fluorescence, and circular dichroism spectroscopic measurements elucidated the protein denaturation and heme dissociation from myoglobin. The results indicated that Empigen BB was not able to fully denature the myoglobin structure, but apparently can induce the dissociation of the heme group from the protein. This provides a way to estimate the heme binding free energy, ΔGdissociation. As ionic liquids (ILs) have been shown to perturb the myoglobin protein, we have investigated the effects of the ILs 1-butyl-3-methylimidazolium chloride (BMICl), 1-ethyl-3-methylimidazolium acetate (EMIAc), and 1-butyl-3-methylimidazolium tetrafluoroborate (BMIBF₄) in aqueous solution on the ΔGdissociation values. Absorbance experiments show the ILs had minimal effect on ΔGdissociation values when compared to controls. Fluorescence and circular dichroism data confirm the ILs have no effect on heme dissociation, demonstrating that low concentrations ILs do not impact the heme dissociation from the protein and do not significantly denature myoglobin on their own or in combination with EBB. These results provide important data for future studies of the mechanism of IL-mediated protein stabilization/destabilization and biocompatibility studies." @default.
• W2899495866 created "2018-11-09" @default.
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• W2899495866 date "2018-10-29" @default.
• W2899495866 modified "2023-10-13" @default.
• W2899495866 title "Heme Dissociation from Myoglobin in the Presence of the Zwitterionic Detergent N,N-Dimethyl-N-Dodecylglycine Betaine: Effects of Ionic Liquids" @default.
• W2899495866 cites W1183872730 @default.
• W2899495866 cites W1486292873 @default.
• W2899495866 cites W1824722086 @default.
• W2899495866 cites W1964680653 @default.
• W2899495866 cites W1974535702 @default.
• W2899495866 cites W1977502625 @default.
• W2899495866 cites W1980623550 @default.
• W2899495866 cites W1980986285 @default.
• W2899495866 cites W1989270637 @default.
• W2899495866 cites W1989674860 @default.
• W2899495866 cites W1991217078 @default.
• W2899495866 cites W1991272887 @default.
• W2899495866 cites W1997776200 @default.
• W2899495866 cites W1997897747 @default.
• W2899495866 cites W2002163515 @default.
• W2899495866 cites W2012434595 @default.
• W2899495866 cites W2014368297 @default.
• W2899495866 cites W2017980560 @default.
• W2899495866 cites W2018289835 @default.
• W2899495866 cites W2021314896 @default.
• W2899495866 cites W2021543172 @default.
• W2899495866 cites W2021676866 @default.
• W2899495866 cites W2032341295 @default.
• W2899495866 cites W2032908530 @default.
• W2899495866 cites W2034051529 @default.
• W2899495866 cites W2035959269 @default.
• W2899495866 cites W2038071783 @default.
• W2899495866 cites W2039883425 @default.
• W2899495866 cites W2049880732 @default.
• W2899495866 cites W2051613968 @default.
• W2899495866 cites W2052596625 @default.
• W2899495866 cites W2059726111 @default.
• W2899495866 cites W2060635190 @default.
• W2899495866 cites W2060871643 @default.
• W2899495866 cites W2071559276 @default.
• W2899495866 cites W2078040293 @default.
• W2899495866 cites W2079386876 @default.
• W2899495866 cites W2080677711 @default.
• W2899495866 cites W2081483078 @default.
• W2899495866 cites W2083586470 @default.
• W2899495866 cites W2084666787 @default.
• W2899495866 cites W2089037490 @default.
• W2899495866 cites W2092113397 @default.
• W2899495866 cites W2093314996 @default.
• W2899495866 cites W2094682784 @default.
• W2899495866 cites W2096246094 @default.
• W2899495866 cites W2100837269 @default.
• W2899495866 cites W2113926549 @default.
• W2899495866 cites W2125823338 @default.
• W2899495866 cites W2125865850 @default.
• W2899495866 cites W2126794322 @default.
• W2899495866 cites W2129380320 @default.
• W2899495866 cites W2142621641 @default.
• W2899495866 cites W2145762385 @default.
• W2899495866 cites W2163268673 @default.
• W2899495866 cites W2169098835 @default.
• W2899495866 cites W2170746519 @default.
• W2899495866 cites W2206309873 @default.
• W2899495866 cites W2315479632 @default.
• W2899495866 cites W2320406870 @default.
• W2899495866 cites W2324095370 @default.
• W2899495866 cites W2328301624 @default.
• W2899495866 cites W2331149165 @default.
• W2899495866 cites W2469469642 @default.
• W2899495866 cites W2515460596 @default.
• W2899495866 cites W2546776228 @default.
• W2899495866 cites W2547743559 @default.
• W2899495866 cites W2580057157 @default.
• W2899495866 cites W2587605981 @default.
• W2899495866 cites W2605469351 @default.
• W2899495866 cites W2613264105 @default.
• W2899495866 cites W2617478919 @default.
• W2899495866 cites W2775973544 @default.
• W2899495866 cites W3023319571 @default.
• W2899495866 cites W2052799588 @default.
• W2899495866 doi "https://doi.org/10.3390/biom8040126" @default.
• W2899495866 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6315634" @default.
• W2899495866 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30380655" @default.
• W2899495866 hasPublicationYear "2018" @default.
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