FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899571024> ?p ?o ?g. }

• W2899571024 endingPage "4879" @default.
• W2899571024 startingPage "4866" @default.
• W2899571024 abstract "The proper shape of dendritic arbors of different types of neurons determines their proper communication within neuronal networks. The shape of dendritic arbors is acquired during a complex and multistep process called dendritogenesis. In most cases, once proper morphology is achieved, it remains stable throughout the lifespan, with the exception of rare events during which dendrites are abruptly pruned. The endosomal sorting complex required for transport (ESCRT) is multisubunit machinery that is involved in various cellular processes when membrane scission is needed. ESCRT subcomplexes regulate dendrite pruning in Drosophila neurons. However, the contribution of ESCRT components to the dendritogenesis of mammalian neurons and control of dendrite stability remains poorly defined. In the present study, we found that ESCRT-0, ESCRT-I, ESCRT-II, and ESCRT-III and Vps4 are required for proper dendrite morphology under basal culture conditions and for accelerated dendritogenesis in response to phosphoinositide 3-kinase (PI3K) activation. The knockdown of Vps28 (ESCRT-I) and Vps25 (ESCRT-II) resulted in downregulation of the activity of mechanistic/mammalian target of rapamycin complex 1. We also demonstrated that Vps28, Vps24, and Vps25 are required for dendrite stabilization in mature neurons." @default.
• W2899571024 created "2018-11-16" @default.
• W2899571024 creator A5036196880 @default.
• W2899571024 creator A5055680087 @default.
• W2899571024 creator A5075647183 @default.
• W2899571024 date "2018-11-07" @default.
• W2899571024 modified "2023-10-17" @default.
• W2899571024 title "ESCRT Proteins Control the Dendritic Morphology of Developing and Mature Hippocampal Neurons" @default.
• W2899571024 cites W1965518769 @default.
• W2899571024 cites W1969693529 @default.
• W2899571024 cites W1973917546 @default.
• W2899571024 cites W1981384224 @default.
• W2899571024 cites W1982237691 @default.
• W2899571024 cites W1982606786 @default.
• W2899571024 cites W1985635613 @default.
• W2899571024 cites W1993155238 @default.
• W2899571024 cites W2020837923 @default.
• W2899571024 cites W2025029519 @default.
• W2899571024 cites W2030054100 @default.
• W2899571024 cites W2032377673 @default.
• W2899571024 cites W2038783205 @default.
• W2899571024 cites W2044161108 @default.
• W2899571024 cites W2047703658 @default.
• W2899571024 cites W2077464949 @default.
• W2899571024 cites W2080946765 @default.
• W2899571024 cites W2089354146 @default.
• W2899571024 cites W2115235864 @default.
• W2899571024 cites W2116489432 @default.
• W2899571024 cites W2154853638 @default.
• W2899571024 cites W2169420582 @default.
• W2899571024 cites W2261452397 @default.
• W2899571024 cites W2296788163 @default.
• W2899571024 cites W2303912672 @default.
• W2899571024 cites W2331735852 @default.
• W2899571024 cites W2341733057 @default.
• W2899571024 cites W2522630538 @default.
• W2899571024 cites W2587163390 @default.
• W2899571024 cites W2601644732 @default.
• W2899571024 cites W2604518186 @default.
• W2899571024 cites W2745047586 @default.
• W2899571024 cites W2746656491 @default.
• W2899571024 doi "https://doi.org/10.1007/s12035-018-1418-9" @default.
• W2899571024 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6647414" @default.
• W2899571024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30406428" @default.
• W2899571024 hasPublicationYear "2018" @default.
• W2899571024 type Work @default.
• W2899571024 sameAs 2899571024 @default.
• W2899571024 citedByCount "6" @default.
• W2899571024 countsByYear W28995710242020 @default.
• W2899571024 countsByYear W28995710242021 @default.
• W2899571024 countsByYear W28995710242022 @default.
• W2899571024 crossrefType "journal-article" @default.
• W2899571024 hasAuthorship W2899571024A5036196880 @default.
• W2899571024 hasAuthorship W2899571024A5055680087 @default.
• W2899571024 hasAuthorship W2899571024A5075647183 @default.
• W2899571024 hasBestOaLocation W28995710241 @default.
• W2899571024 hasConcept C102747710 @default.
• W2899571024 hasConcept C104317684 @default.
• W2899571024 hasConcept C143876685 @default.
• W2899571024 hasConcept C145059251 @default.
• W2899571024 hasConcept C169760540 @default.
• W2899571024 hasConcept C173396325 @default.
• W2899571024 hasConcept C20518536 @default.
• W2899571024 hasConcept C2524010 @default.
• W2899571024 hasConcept C2778283623 @default.
• W2899571024 hasConcept C33923547 @default.
• W2899571024 hasConcept C55493867 @default.
• W2899571024 hasConcept C79879829 @default.
• W2899571024 hasConcept C84248122 @default.
• W2899571024 hasConcept C86803240 @default.
• W2899571024 hasConcept C95444343 @default.
• W2899571024 hasConceptScore W2899571024C102747710 @default.
• W2899571024 hasConceptScore W2899571024C104317684 @default.
• W2899571024 hasConceptScore W2899571024C143876685 @default.
• W2899571024 hasConceptScore W2899571024C145059251 @default.
• W2899571024 hasConceptScore W2899571024C169760540 @default.
• W2899571024 hasConceptScore W2899571024C173396325 @default.
• W2899571024 hasConceptScore W2899571024C20518536 @default.
• W2899571024 hasConceptScore W2899571024C2524010 @default.
• W2899571024 hasConceptScore W2899571024C2778283623 @default.
• W2899571024 hasConceptScore W2899571024C33923547 @default.
• W2899571024 hasConceptScore W2899571024C55493867 @default.
• W2899571024 hasConceptScore W2899571024C79879829 @default.
• W2899571024 hasConceptScore W2899571024C84248122 @default.
• W2899571024 hasConceptScore W2899571024C86803240 @default.
• W2899571024 hasConceptScore W2899571024C95444343 @default.
• W2899571024 hasFunder F4320322511 @default.
• W2899571024 hasIssue "7" @default.
• W2899571024 hasLocation W28995710241 @default.
• W2899571024 hasLocation W28995710242 @default.
• W2899571024 hasLocation W28995710243 @default.
• W2899571024 hasLocation W28995710244 @default.
• W2899571024 hasOpenAccess W2899571024 @default.
• W2899571024 hasPrimaryLocation W28995710241 @default.
• W2899571024 hasRelatedWork W1998307755 @default.
• W2899571024 hasRelatedWork W2027048169 @default.
• W2899571024 hasRelatedWork W2046416187 @default.
• W2899571024 hasRelatedWork W2056979920 @default.

• next