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- W2899572044 abstract "Chemical investigation of the mangrove-derived fungus Aspergillus sp. AV-2 following fermentation on solid rice medium led to the isolation of a new phenyl pyridazine derivative (1) and a new prenylated benzaldehyde derivative, dioxoauroglaucin (2), together with fourteen known compounds (3-16). Chemical structures of the new compounds were unambiguously determined based on HRESIMS and extensive 1D and 2D NMR spectroscopic analyses. Compounds 2-7, 8 and 13 were assessed for their antiproliferative activity against Caco-2 cell lines, where flavoglaucin (6) revealed the most potent cytotoxicity with IC50 of 2.87 μM." @default.
- W2899572044 created "2018-11-16" @default.
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- W2899572044 date "2019-02-01" @default.
- W2899572044 modified "2023-09-27" @default.
- W2899572044 title "New secondary metabolites from the mangrove-derived fungus Aspergillus sp. AV-2" @default.
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- W2899572044 doi "https://doi.org/10.1016/j.phytol.2018.10.014" @default.
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