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- W2899596906 abstract "The involvement of macrophages in the pathogenesis of obesity has been recognized since 2003. Early studies mostly focused on the role of macrophages in adipose tissue (AT) and in obesity-associated chronic low-grade inflammation. Lately, AT macrophages were shown to undergo intrinsic metabolic changes that affect their immune function (i.e., immunometabolism), corresponding to their unique properties along the range of pro- versus anti-inflammatory activity. In parallel, recent studies in mice revealed critical neuronal-macrophage interactions, both in the CNS and in peripheral tissues, including in white and brown AT. These intercellular activities impinge on energy and metabolic homeostasis, partially by also engaging adipocytes in a neuronal-macrophage-adipocyte ménage à trois. Finally, neuropeptides (NP), such as NPY and appetite-reducing NPFF, may prove as mediators in such intercellular network. In this concise review, we highlight some of these recent insights on adipose macrophage immunometabolism, as well as central and peripheral neuronal-macrophage interactions with emphasis on their impact on adipocyte biology and whole-body metabolism. We also discuss the expanding view on the role of the NP, NPY and NPFF, in obesity." @default.
- W2899596906 created "2018-11-16" @default.
- W2899596906 creator A5014740581 @default.
- W2899596906 creator A5044242375 @default.
- W2899596906 creator A5075764103 @default.
- W2899596906 creator A5085718942 @default.
- W2899596906 date "2018-11-16" @default.
- W2899596906 modified "2023-10-16" @default.
- W2899596906 title "Obesity and dysregulated central and peripheral macrophage–neuron cross‐talk" @default.
- W2899596906 cites W1241697 @default.
- W2899596906 cites W1544249031 @default.
- W2899596906 cites W1548584275 @default.
- W2899596906 cites W1557523315 @default.
- W2899596906 cites W1836764230 @default.
- W2899596906 cites W1942079413 @default.
- W2899596906 cites W1964562779 @default.
- W2899596906 cites W1965750048 @default.
- W2899596906 cites W1968994158 @default.
- W2899596906 cites W1971122483 @default.
- W2899596906 cites W1972801970 @default.
- W2899596906 cites W1976844022 @default.
- W2899596906 cites W1979514353 @default.
- W2899596906 cites W1985761935 @default.
- W2899596906 cites W1985929369 @default.
- W2899596906 cites W1986342371 @default.
- W2899596906 cites W1988413422 @default.
- W2899596906 cites W1989090840 @default.
- W2899596906 cites W1989823340 @default.
- W2899596906 cites W1992304191 @default.
- W2899596906 cites W1995056798 @default.
- W2899596906 cites W1996645236 @default.
- W2899596906 cites W2004144873 @default.
- W2899596906 cites W2011255130 @default.
- W2899596906 cites W2015666335 @default.
- W2899596906 cites W2016662511 @default.
- W2899596906 cites W2020447893 @default.
- W2899596906 cites W2024436287 @default.
- W2899596906 cites W2025131475 @default.
- W2899596906 cites W2031874852 @default.
- W2899596906 cites W2033617297 @default.
- W2899596906 cites W2048733541 @default.
- W2899596906 cites W2050966149 @default.
- W2899596906 cites W2054544693 @default.
- W2899596906 cites W2054828149 @default.
- W2899596906 cites W2055348159 @default.
- W2899596906 cites W2055421595 @default.
- W2899596906 cites W2058021161 @default.
- W2899596906 cites W2060813891 @default.
- W2899596906 cites W2063131576 @default.
- W2899596906 cites W2064173000 @default.
- W2899596906 cites W2067875627 @default.
- W2899596906 cites W2069503929 @default.
- W2899596906 cites W2070197168 @default.
- W2899596906 cites W2075792687 @default.
- W2899596906 cites W2077033935 @default.
- W2899596906 cites W2077745556 @default.
- W2899596906 cites W2078707624 @default.
- W2899596906 cites W2083666530 @default.
- W2899596906 cites W2085158900 @default.
- W2899596906 cites W2085792819 @default.
- W2899596906 cites W2090070160 @default.
- W2899596906 cites W2093598827 @default.
- W2899596906 cites W2096551871 @default.
- W2899596906 cites W2101630550 @default.
- W2899596906 cites W2106427090 @default.
- W2899596906 cites W2107550410 @default.
- W2899596906 cites W2113107925 @default.
- W2899596906 cites W2113511371 @default.
- W2899596906 cites W2115949387 @default.
- W2899596906 cites W2124688365 @default.
- W2899596906 cites W2125914461 @default.
- W2899596906 cites W2126263479 @default.
- W2899596906 cites W2126811287 @default.
- W2899596906 cites W2128076606 @default.
- W2899596906 cites W2129973062 @default.
- W2899596906 cites W2133999017 @default.
- W2899596906 cites W2139273810 @default.
- W2899596906 cites W2139716106 @default.
- W2899596906 cites W2139754172 @default.
- W2899596906 cites W2141189887 @default.
- W2899596906 cites W2142793823 @default.
- W2899596906 cites W2145697808 @default.
- W2899596906 cites W2145826454 @default.
- W2899596906 cites W2149472502 @default.
- W2899596906 cites W2150586369 @default.
- W2899596906 cites W2154478876 @default.
- W2899596906 cites W2154696002 @default.
- W2899596906 cites W2156280702 @default.
- W2899596906 cites W2158070898 @default.
- W2899596906 cites W2159744102 @default.
- W2899596906 cites W2159841585 @default.
- W2899596906 cites W2162166699 @default.
- W2899596906 cites W2163774748 @default.
- W2899596906 cites W2165202791 @default.
- W2899596906 cites W2170007502 @default.
- W2899596906 cites W2209939113 @default.
- W2899596906 cites W2232938630 @default.
- W2899596906 cites W2316027465 @default.