FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899610338> ?p ?o ?g. }

• W2899610338 endingPage "23" @default.
• W2899610338 startingPage "17" @default.
• W2899610338 abstract "Perfluorooctane sulfonyl fluoride (PFOSF) has been defined as persistent organic pollutant in the Stockholm Convention in 2009. Currently PFOSF and its substitutes (structural analogues in which octyl group is substituted for other aliphatic chains) are still scarcely studied. HSA is a main carrier for drugs in blood, and the influence of exogenous compounds including pollutants on HSA is of particular interest. In this work, the binding sites of HSA to Perfluoroalkane sulfonyl fluoride (PFASFs) were determined by fluorescence technique. The results demonstrated that PFASFs competitively bind to HSA at Sudlow’s site I against warfarin and at Sudlow’s site II against dansyl-proline and the related association constants were determined. The association constants of PFOSF, perfluorohexane sulfonyl fluoride (PFHSF) and perfluorobutane sulfonyl fluoride (PFBSF) were determined to be 2.59 × 10−3 μM-1, 4.65 × 10−3 μM-1 and 2.85 × 10−3 μM-1 at Sudlow’s site I and 8.68 × 10−4 μM-1, 3.43 × 10−2 μM-1 and 1.92 × 10−2 μM-1 at Sudlow’s site II, respectively. The results showed that PFASFs can bind tightly to HSA and thus migrate to all parts of the body through vascular system. Non-covalent interaction between HSA and PFASFs was confirmed with tryptic digestion experiment. The mass spectra results indicated that other binding sites of HSA are also involved in the binding of PFHSF and PFBSF. The total binding numbers of PFOSF, PFHSF and PFBSF on HSA are 2, 6 and 3, respectively." @default.
• W2899610338 created "2018-11-16" @default.
• W2899610338 creator A5011308113 @default.
• W2899610338 creator A5037713427 @default.
• W2899610338 creator A5042034585 @default.
• W2899610338 creator A5057708297 @default.
• W2899610338 creator A5058615607 @default.
• W2899610338 date "2019-02-01" @default.
• W2899610338 modified "2023-10-16" @default.
• W2899610338 title "Perfluoroalkane sulfonyl fluorides non-covalently bind to human serum albumin at Sudlow’s sites" @default.
• W2899610338 cites W1871594197 @default.
• W2899610338 cites W1970016764 @default.
• W2899610338 cites W1972074055 @default.
• W2899610338 cites W1973788406 @default.
• W2899610338 cites W1975586699 @default.
• W2899610338 cites W1980078657 @default.
• W2899610338 cites W1982257539 @default.
• W2899610338 cites W1983070240 @default.
• W2899610338 cites W1993650845 @default.
• W2899610338 cites W1994081865 @default.
• W2899610338 cites W2014477053 @default.
• W2899610338 cites W2017654147 @default.
• W2899610338 cites W2019656832 @default.
• W2899610338 cites W2043672781 @default.
• W2899610338 cites W2048120157 @default.
• W2899610338 cites W2062857689 @default.
• W2899610338 cites W2072694732 @default.
• W2899610338 cites W2073051414 @default.
• W2899610338 cites W2078941665 @default.
• W2899610338 cites W2101992164 @default.
• W2899610338 cites W2210065143 @default.
• W2899610338 cites W2211324615 @default.
• W2899610338 cites W2331805178 @default.
• W2899610338 cites W2510758121 @default.
• W2899610338 cites W2573991901 @default.
• W2899610338 cites W2594789274 @default.
• W2899610338 cites W2598270026 @default.
• W2899610338 cites W2602988735 @default.
• W2899610338 cites W2616208216 @default.
• W2899610338 cites W2753819448 @default.
• W2899610338 cites W2782179373 @default.
• W2899610338 cites W2792105926 @default.
• W2899610338 cites W2794857760 @default.
• W2899610338 cites W4246863443 @default.
• W2899610338 cites W2260954955 @default.
• W2899610338 doi "https://doi.org/10.1016/j.toxlet.2018.11.001" @default.
• W2899610338 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30408508" @default.
• W2899610338 hasPublicationYear "2019" @default.
• W2899610338 type Work @default.
• W2899610338 sameAs 2899610338 @default.
• W2899610338 citedByCount "10" @default.
• W2899610338 countsByYear W28996103382019 @default.
• W2899610338 countsByYear W28996103382020 @default.
• W2899610338 countsByYear W28996103382021 @default.
• W2899610338 countsByYear W28996103382022 @default.
• W2899610338 countsByYear W28996103382023 @default.
• W2899610338 crossrefType "journal-article" @default.
• W2899610338 hasAuthorship W2899610338A5011308113 @default.
• W2899610338 hasAuthorship W2899610338A5037713427 @default.
• W2899610338 hasAuthorship W2899610338A5042034585 @default.
• W2899610338 hasAuthorship W2899610338A5057708297 @default.
• W2899610338 hasAuthorship W2899610338A5058615607 @default.
• W2899610338 hasConcept C107824862 @default.
• W2899610338 hasConcept C178790620 @default.
• W2899610338 hasConcept C180577832 @default.
• W2899610338 hasConcept C185592680 @default.
• W2899610338 hasConcept C2778597219 @default.
• W2899610338 hasConcept C2780263894 @default.
• W2899610338 hasConcept C43617362 @default.
• W2899610338 hasConcept C55493867 @default.
• W2899610338 hasConcept C71240020 @default.
• W2899610338 hasConcept C87906975 @default.
• W2899610338 hasConceptScore W2899610338C107824862 @default.
• W2899610338 hasConceptScore W2899610338C178790620 @default.
• W2899610338 hasConceptScore W2899610338C180577832 @default.
• W2899610338 hasConceptScore W2899610338C185592680 @default.
• W2899610338 hasConceptScore W2899610338C2778597219 @default.
• W2899610338 hasConceptScore W2899610338C2780263894 @default.
• W2899610338 hasConceptScore W2899610338C43617362 @default.
• W2899610338 hasConceptScore W2899610338C55493867 @default.
• W2899610338 hasConceptScore W2899610338C71240020 @default.
• W2899610338 hasConceptScore W2899610338C87906975 @default.
• W2899610338 hasFunder F4320321001 @default.
• W2899610338 hasLocation W28996103381 @default.
• W2899610338 hasLocation W28996103382 @default.
• W2899610338 hasOpenAccess W2899610338 @default.
• W2899610338 hasPrimaryLocation W28996103381 @default.
• W2899610338 hasRelatedWork W1986911541 @default.
• W2899610338 hasRelatedWork W1997594337 @default.
• W2899610338 hasRelatedWork W2042231674 @default.
• W2899610338 hasRelatedWork W2081343466 @default.
• W2899610338 hasRelatedWork W2138114719 @default.
• W2899610338 hasRelatedWork W2160387324 @default.
• W2899610338 hasRelatedWork W2338193514 @default.
• W2899610338 hasRelatedWork W2950978701 @default.
• W2899610338 hasRelatedWork W2952861236 @default.
• W2899610338 hasRelatedWork W2184911279 @default.
• W2899610338 hasVolume "301" @default.

• next