FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899685562> ?p ?o ?g. }

• W2899685562 endingPage "106" @default.
• W2899685562 startingPage "99" @default.
• W2899685562 abstract "Protein kinase A, a cyclic adenosine monophosphate (AMP)-dependent enzyme, normally exists within mammalian cells; however, in cancer cells, it can leak out and be found in the serum. Extracellular cyclic AMP-dependent protein kinase A (ECPKA) has been determined to increase in the serum of cancer-bearing dogs. However, there have been no reports in the veterinary literature on serum ECPKA autoantibody (ECPKA-Ab) expression in dogs with cancer. The aim of this study was to evaluate ECPKA-Ab and C-reactive protein (CRP) as serum biomarkers for cancer in dogs. ECPKA-Ab and CRP levels were detected by an enzyme-linked immunosorbent assay in serum samples from dogs with malignant tumours (n = 167), benign tumours (n = 42), or non-tumour disease (n = 155) and from healthy control dogs (n = 123). ECPKA-Ab and CRP levels were significantly higher in the dogs with malignant tumours than in those with benign tumours or non-tumour diseases, as well as in the healthy controls (P < 0.001, Kruskal-Wallis test). There was a significant positive correlation between the neoplastic index, which was developed using ECPKA-Ab and CRP levels, and the presence of cancer in dogs (P < 0.001); the area under the receiver-operating characteristic curve was estimated to be >0.85 (P < 0.001). In conclusion, ECPKA-Ab is a potential serum biomarker for a broad spectrum of cancers. Combined measurement of CRP and ECPKA-Ab levels in serum improves the sensitivity and accuracy of a diagnosis of cancer in dogs." @default.
• W2899685562 created "2018-11-16" @default.
• W2899685562 creator A5000251765 @default.
• W2899685562 creator A5006448703 @default.
• W2899685562 creator A5017960982 @default.
• W2899685562 creator A5020933495 @default.
• W2899685562 creator A5028807480 @default.
• W2899685562 creator A5045541621 @default.
• W2899685562 creator A5059493453 @default.
• W2899685562 creator A5069771802 @default.
• W2899685562 creator A5071214940 @default.
• W2899685562 creator A5078770585 @default.
• W2899685562 date "2018-11-28" @default.
• W2899685562 modified "2023-10-18" @default.
• W2899685562 title "Extracellular cyclic adenosine monophosphate‐dependent protein kinase A autoantibody and C‐reactive protein as serum biomarkers for diagnosis of cancer in dogs" @default.
• W2899685562 cites W195613315 @default.
• W2899685562 cites W1970720658 @default.
• W2899685562 cites W1974985535 @default.
• W2899685562 cites W1978441935 @default.
• W2899685562 cites W1990891357 @default.
• W2899685562 cites W1995287920 @default.
• W2899685562 cites W1995386393 @default.
• W2899685562 cites W2001655957 @default.
• W2899685562 cites W2013187066 @default.
• W2899685562 cites W2036349474 @default.
• W2899685562 cites W2039538740 @default.
• W2899685562 cites W2062722009 @default.
• W2899685562 cites W2074851000 @default.
• W2899685562 cites W2074892800 @default.
• W2899685562 cites W2076116687 @default.
• W2899685562 cites W2085757616 @default.
• W2899685562 cites W2096557480 @default.
• W2899685562 cites W2096846592 @default.
• W2899685562 cites W2104657191 @default.
• W2899685562 cites W2112657305 @default.
• W2899685562 cites W2125215650 @default.
• W2899685562 cites W2129967741 @default.
• W2899685562 cites W2133794613 @default.
• W2899685562 cites W2151988023 @default.
• W2899685562 cites W2168539910 @default.
• W2899685562 cites W2195692730 @default.
• W2899685562 cites W2235523093 @default.
• W2899685562 cites W2407594203 @default.
• W2899685562 cites W2586842434 @default.
• W2899685562 cites W2899685562 @default.
• W2899685562 cites W2984936299 @default.
• W2899685562 cites W98051250 @default.
• W2899685562 doi "https://doi.org/10.1111/vco.12450" @default.
• W2899685562 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6375080" @default.
• W2899685562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30411459" @default.
• W2899685562 hasPublicationYear "2018" @default.
• W2899685562 type Work @default.
• W2899685562 sameAs 2899685562 @default.
• W2899685562 citedByCount "11" @default.
• W2899685562 countsByYear W28996855622018 @default.
• W2899685562 countsByYear W28996855622019 @default.
• W2899685562 countsByYear W28996855622020 @default.
• W2899685562 countsByYear W28996855622021 @default.
• W2899685562 countsByYear W28996855622022 @default.
• W2899685562 countsByYear W28996855622023 @default.
• W2899685562 crossrefType "journal-article" @default.
• W2899685562 hasAuthorship W2899685562A5000251765 @default.
• W2899685562 hasAuthorship W2899685562A5006448703 @default.
• W2899685562 hasAuthorship W2899685562A5017960982 @default.
• W2899685562 hasAuthorship W2899685562A5020933495 @default.
• W2899685562 hasAuthorship W2899685562A5028807480 @default.
• W2899685562 hasAuthorship W2899685562A5045541621 @default.
• W2899685562 hasAuthorship W2899685562A5059493453 @default.
• W2899685562 hasAuthorship W2899685562A5069771802 @default.
• W2899685562 hasAuthorship W2899685562A5071214940 @default.
• W2899685562 hasAuthorship W2899685562A5078770585 @default.
• W2899685562 hasBestOaLocation W28996855621 @default.
• W2899685562 hasConcept C121608353 @default.
• W2899685562 hasConcept C126322002 @default.
• W2899685562 hasConcept C134018914 @default.
• W2899685562 hasConcept C142724271 @default.
• W2899685562 hasConcept C159654299 @default.
• W2899685562 hasConcept C163764329 @default.
• W2899685562 hasConcept C170493617 @default.
• W2899685562 hasConcept C181199279 @default.
• W2899685562 hasConcept C184235292 @default.
• W2899685562 hasConcept C185592680 @default.
• W2899685562 hasConcept C203014093 @default.
• W2899685562 hasConcept C2776668983 @default.
• W2899685562 hasConcept C2776914184 @default.
• W2899685562 hasConcept C2781195455 @default.
• W2899685562 hasConcept C2781197716 @default.
• W2899685562 hasConcept C28406088 @default.
• W2899685562 hasConcept C55493867 @default.
• W2899685562 hasConcept C71924100 @default.
• W2899685562 hasConcept C97029542 @default.
• W2899685562 hasConceptScore W2899685562C121608353 @default.
• W2899685562 hasConceptScore W2899685562C126322002 @default.
• W2899685562 hasConceptScore W2899685562C134018914 @default.
• W2899685562 hasConceptScore W2899685562C142724271 @default.
• W2899685562 hasConceptScore W2899685562C159654299 @default.
• W2899685562 hasConceptScore W2899685562C163764329 @default.
• W2899685562 hasConceptScore W2899685562C170493617 @default.

• next