FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2899688066> ?p ?o ?g. }

• W2899688066 abstract "Abstract The L strain of Japanese quail exhibits a plumage phenotype that is light yellowish in colour. In this study, we identified a nonsense mutation in the premelanosome protein ( PMEL ) gene showing complete concordance with the yellowish plumage within a pedigree as well as across strains by genetic linkage analysis of an F 2 intercross population using approximately 2,000 single nucleotide polymorphisms (SNPs) that were detected by double digest restriction site-associated DNA sequencing (ddRAD-seq). The yellowish plumage was inherited in an autosomal recessive manner, and the causative mutation was located within an 810-kb genomic region of the LGE22C19W28_E50C23 linkage group (LGE22). This region contained the PMEL gene that is required for the normal melanosome morphogenesis and eumelanin deposition. A nonsense mutation that leads to a marked truncation of the deduced protein was found in PMEL of the mutant. The gene expression level of PMEL decreased substantially in the mutant. Genotypes at the site of the nonsense mutation were fully concordant with plumage colour phenotypes in 196 F 2 offspring. The nonsense mutation was not found in several quail strains with non-yellowish plumage. Thus, the yellowish plumage may be caused by the reduced eumelanin content in feathers because of the loss of PMEL function." @default.
• W2899688066 created "2018-11-16" @default.
• W2899688066 creator A5007966953 @default.
• W2899688066 creator A5014301141 @default.
• W2899688066 creator A5032674185 @default.
• W2899688066 creator A5035270950 @default.
• W2899688066 creator A5047402344 @default.
• W2899688066 creator A5049454213 @default.
• W2899688066 creator A5060579865 @default.
• W2899688066 creator A5074581022 @default.
• W2899688066 creator A5082002376 @default.
• W2899688066 creator A5086767802 @default.
• W2899688066 creator A5091026390 @default.
• W2899688066 date "2018-11-13" @default.
• W2899688066 modified "2023-09-26" @default.
• W2899688066 title "Nonsense mutation in PMEL is associated with yellowish plumage colour phenotype in Japanese quail" @default.
• W2899688066 cites W1483826831 @default.
• W2899688066 cites W1497909849 @default.
• W2899688066 cites W1566787063 @default.
• W2899688066 cites W1651738511 @default.
• W2899688066 cites W1847444640 @default.
• W2899688066 cites W1965167656 @default.
• W2899688066 cites W1970346375 @default.
• W2899688066 cites W1974607230 @default.
• W2899688066 cites W1974721505 @default.
• W2899688066 cites W1975616681 @default.
• W2899688066 cites W1977441374 @default.
• W2899688066 cites W1977604267 @default.
• W2899688066 cites W1983009742 @default.
• W2899688066 cites W1996112179 @default.
• W2899688066 cites W2040546508 @default.
• W2899688066 cites W2048319565 @default.
• W2899688066 cites W2049051544 @default.
• W2899688066 cites W2049432953 @default.
• W2899688066 cites W2057452550 @default.
• W2899688066 cites W2060537320 @default.
• W2899688066 cites W2061959831 @default.
• W2899688066 cites W2062018530 @default.
• W2899688066 cites W2062101561 @default.
• W2899688066 cites W2063423234 @default.
• W2899688066 cites W2064177674 @default.
• W2899688066 cites W2066615572 @default.
• W2899688066 cites W2074095545 @default.
• W2899688066 cites W2076379612 @default.
• W2899688066 cites W2087077130 @default.
• W2899688066 cites W2094179893 @default.
• W2899688066 cites W2097252617 @default.
• W2899688066 cites W2100265472 @default.
• W2899688066 cites W2109472451 @default.
• W2899688066 cites W2111274886 @default.
• W2899688066 cites W2114570899 @default.
• W2899688066 cites W2119924680 @default.
• W2899688066 cites W2133187342 @default.
• W2899688066 cites W2135017237 @default.
• W2899688066 cites W2135632785 @default.
• W2899688066 cites W2150245940 @default.
• W2899688066 cites W2152485207 @default.
• W2899688066 cites W2152584268 @default.
• W2899688066 cites W2154362297 @default.
• W2899688066 cites W2155341559 @default.
• W2899688066 cites W2161184021 @default.
• W2899688066 cites W2161633633 @default.
• W2899688066 cites W2161901637 @default.
• W2899688066 cites W2162911475 @default.
• W2899688066 cites W2171464702 @default.
• W2899688066 cites W2203734331 @default.
• W2899688066 cites W2275071934 @default.
• W2899688066 cites W2515264152 @default.
• W2899688066 cites W2579390238 @default.
• W2899688066 cites W4210702584 @default.
• W2899688066 doi "https://doi.org/10.1038/s41598-018-34827-4" @default.
• W2899688066 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6233202" @default.
• W2899688066 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30425278" @default.
• W2899688066 hasPublicationYear "2018" @default.
• W2899688066 type Work @default.
• W2899688066 sameAs 2899688066 @default.
• W2899688066 citedByCount "15" @default.
• W2899688066 countsByYear W28996880662019 @default.
• W2899688066 countsByYear W28996880662020 @default.
• W2899688066 countsByYear W28996880662021 @default.
• W2899688066 countsByYear W28996880662022 @default.
• W2899688066 countsByYear W28996880662023 @default.
• W2899688066 crossrefType "journal-article" @default.
• W2899688066 hasAuthorship W2899688066A5007966953 @default.
• W2899688066 hasAuthorship W2899688066A5014301141 @default.
• W2899688066 hasAuthorship W2899688066A5032674185 @default.
• W2899688066 hasAuthorship W2899688066A5035270950 @default.
• W2899688066 hasAuthorship W2899688066A5047402344 @default.
• W2899688066 hasAuthorship W2899688066A5049454213 @default.
• W2899688066 hasAuthorship W2899688066A5060579865 @default.
• W2899688066 hasAuthorship W2899688066A5074581022 @default.
• W2899688066 hasAuthorship W2899688066A5082002376 @default.
• W2899688066 hasAuthorship W2899688066A5086767802 @default.
• W2899688066 hasAuthorship W2899688066A5091026390 @default.
• W2899688066 hasBestOaLocation W28996880661 @default.
• W2899688066 hasConcept C104317684 @default.
• W2899688066 hasConcept C134018914 @default.
• W2899688066 hasConcept C143065580 @default.
• W2899688066 hasConcept C151730666 @default.
• W2899688066 hasConcept C2777882087 @default.

• next