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- W2899690016 abstract "We instituted early clean intermittent catheterization (CIC) in 1997 for all newborn infants with spina bifida (SB). We compared this group to a historical group managed expectantly to see if early catheterization was associated with a reduction in renal scar rate as determined by DMSA scanning.Data were studied retrospectively on all infants with SB over a recent 13-year period who were treated with early universal CIC in a regional pediatric urology department. These were compared to our previously published outcomes in a historical group (1985-1994) that was managed expectantly [Brown et al. Chronic pyelonephritis in association with neuropathic bladder. Eur J Pediatr Surg 1999;9 Suppl 1:29-30.] RESULTS: 114 infants were born with SB from 1997 to 2010, of which 13 were excluded from this analysis. Mean follow-up was 11.4 years. In the historical cohort there were 126 infants born from 1985 to 1994, with 26 exclusions; follow-up then ranged from 4 to 13 years. DMSA scan showed renal scarring in 19/101 (18.8%) of the recent cohort versus 39/100 (39%) of the previous group (P = 0.002). Renal scarring at a later age also appeared to be a feature of the recent group, with first detection occuring by 4 years in only 9/19 (47%) in the latest cohort compared to 28/39 (72%) in the historical cohort.Based on these renal protective data, we recommend indwelling and then intermittent catheterization from birth in all patients with SB.Level III.Retrospective, cohort comparison study." @default.
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- W2899690016 date "2019-02-01" @default.
- W2899690016 modified "2023-09-30" @default.
- W2899690016 title "Early start of clean intermittent catheterization versus expectant management in children with spina bifida" @default.
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- W2899690016 doi "https://doi.org/10.1016/j.jpedsurg.2018.10.096" @default.
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